greenfylde
Mind Map by , created almost 6 years ago

FOCP- GI Mind Map on Jaundice, created by greenfylde on 11/22/2013.

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greenfylde
Created by greenfylde almost 6 years ago
Liver disorders
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Jaundice
1 Acute liver injury (including hepatitis)
1.1 infective
1.1.1 acute viral hepatitis (A,B,E), CMV, EBV
1.1.2 jaundice commonly preceded by 1-2w prodrome
1.2 autoimmune
1.2.1 autoimmune hepatitis
1.3 toxic
1.3.1 paracetamol overdose, antiTB drugs, ecstasy, halothane
1.4 metabolic
1.4.1 Wilson's disease
1.5 vascular
1.5.1 shock/ishchemic hepatitis, Budd-Chiari syndrome
1.6 other: acute fatty liver of preg, extensive malignant infiltration
2 Cirrhosis
2.1 chronic liver inj from any cause
2.2 pathphys: hepatocell fail -> jaundice, coagulopathy, decreased albumin. portal hypertension -> esoph varices, hepatic encephalopathy.
2.2.1 portal hypertens + decreased albumin + generalised salt and water retention -> ascites
3 Hepatic tumors
3.1 malignant infiltration by py or metastatic tumors -> jaundice b/c replace liver parenchyma or hepatic duct obstruction
3.2 assoc feats: cachexia, malaise, RUQ pain, hepatomegaly
4 Biliary disease
4.1 jaundice due to biliary obstruction
4.1.1 py biliary cirrhosis, py sclerosing scholangitis, extrahepatic cholestasis- most often caused by gallstones, benign strictures, cholangiocarcinoma, pancreatic carcinoma
4.2 increased ALP + GGT
4.3 assoc: pale stools, dark urine, itch
5 No hepatobiliary disease
5.1 hemolytic disorders
5.1.1 gilbert's syndrome (congen, 2-5% pop, decreased enzymatic activity so limits conjugation)
6 cause: increased hemolysis, decreased uptake/conjugation by liver, imparied biliary drainage (cholestasis)

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