SOURCES OF VARIATION IN A GENE POOL

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Mind Map describing Sources of Variation in a Gene Pool. Designed for NCEA Biology Level Two exam on Genetic Variation and Change.
benhay61
Mind Map by benhay61, updated more than 1 year ago More Less
Eilidh Young
Created by Eilidh Young over 8 years ago
benhay61
Copied by benhay61 over 8 years ago
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Resource summary

SOURCES OF VARIATION IN A GENE POOL
  1. Mutation
    1. A mutation is a permanent change in the base sequence of DNA
      1. Mutations can be: 1. silent, 2. harmful, 3. beneficial
        1. Somatic mutations can't enter gene pool
          1. Mutations can occur during DNA replication or from mutagens
          2. Independent Assortment
            1. When homologous pairs of chromosomes line up during meiosis, they do so randomly
              1. This means it is completely random which combination of alleles ends up in a particular gamete
            2. Segregation
              1. Pairs of alleles are segregated when the homologous chromosomes split so that each gamete receives one allele
                1. Segregation results in all daughter cells being unique
              2. Crossing Over
                1. Occurs when homologous pairs of chromosomes line up on cell equator and parts of neighbouring chromosomes cross over
                  1. These sections are then exchanged and each gamete produced has a different combination of alleles
                2. Dihybrid Inheritance
                  1. Dihybrid crosses involve two genes, and four alleles
                    1. These genes are linked if they are on the same chromosome, and the closer together they are on the chromosome, the less likely they will be separated during crossing over
                      1. They will therefore be inherited together and reduce the number of possible combinations of alleles in gametes
                      2. Where there is no linkage expected phenotype ratio is 9:3:3:1
                        1. Where this is not the case the genes are most likely linked
                    2. Monohybrid Inheritance
                      1. Co-dominance
                        1. Where a single gene has more than one dominant allele
                          1. An organism heterozygous for both dominant alleles with have both expressed in the phenotype (MIXTURE)
                        2. Multiple Alleles
                          1. Multiple alleles exist due to mutations in a single gene resulting in more than two alleles for that gene e.g. human blood type
                          2. Lethal Alleles
                            1. Lethal alleles code for a phenotype that causes the death of an organism
                              1. Changes expected phenotype ratio
                              2. It usually arises as a result of a mutation in an essential gene cauusing the gene to no longer produce a functioning version of an essential protein
                              3. Incomplete Dominance
                                1. Where in a single gene the two alleles are not dominant over each other
                                  1. The resulting phenotype is a BLEND of the two alleles
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