4479965
PDH
- PDH Phosphatase Activates PDH
- PDH (Inactive)
- Phosphorylated
- Phosphorylated
- To Activate PDH Phosphatase
- Increased Mg2+ & Ca2+, available from muscular contraction
- Increased Mg2+ & Ca2+, available from muscular contraction
- PDH (Inactive)
- PDH Kinase Deactivates PDH
- To Deactivate PDH kinase
- Increased levels of pyruvate, NAD+, CoASH, ADP and Ca2+
- CA2+ from muscle contraction
- During exercise pyruvate increases due to enhanced glycolysis
= PDH activated. ADP increases due to ATP hydrolysis
- CA2+ from muscle contraction
- Increased levels of pyruvate, NAD+, CoASH, ADP and Ca2+
- To activate PDH Kinase
- Increased levels of ATP, NADH and Acetyl CoA
- When glycolysis and beta-oxidation occur
rapidly result in build up of acetyl CoA.
- When glycolysis and beta-oxidation occur
rapidly result in build up of acetyl CoA.
- Increased levels of ATP, NADH and Acetyl CoA
- PDH (Inactive)
- To Deactivate PDH kinase
- Dephosphorylated
- Forms acetyl CoA from Pyruvate
- Regulates CHO and Lipid oxidation
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