Nucleic Acids

Chloe Foulkes
Mind Map by Chloe Foulkes, updated more than 1 year ago
Chloe Foulkes
Created by Chloe Foulkes over 5 years ago
32
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Description

Bachelors Degree Bionanophysics Mind Map on Nucleic Acids, created by Chloe Foulkes on 03/01/2016.

Resource summary

Nucleic Acids
  1. Electromagnetic Force
    1. Only relevant force for this scale
      1. All intermolecular forces
        1. Charge mediated
          1. Attractive and Repulsive
          2. F(r)=-(nCm1m2)/r^(n+1)
            1. Long range interactions disappear for n>3
              1. Lennard- Jones type potential graphs
                1. Positive energy = Repulsive force
                  1. Negative energy = Attractive Force
                    1. Lennard- Jones: V(r)= -A/r^6 + B/r^12
                  2. Polymers
                    1. Made up of monomers
                      1. Joined via covalent bonds
                      2. Degree of polymization = number of monomers = N
                        1. Mass of polymer= Nm(mon)
                          1. Types
                            1. Homopolymers
                              1. Same monomer
                              2. Heteropolymer
                                1. Different monomers
                                  1. Random
                                    1. Block
                                2. Flexibility
                                  1. Coil
                                    1. Rod
                                      1. Depends on length scale
                                      2. Isomerisation
                                        1. Isotatic
                                          1. Chemical group always in same position
                                          2. Syndiotactic
                                            1. Chemical group swaps sides
                                            2. Atactic
                                              1. Chemical group in random positon
                                            3. Topology
                                              1. Linear
                                                1. Ring
                                                  1. Branched
                                                2. Molecular Conformations
                                                  1. Free Jointed Chain (FJC) Model
                                                    1. Mean squared value= Cn*n*l^2
                                                      1. Cn=Flory Characteristic Ratio – average of all Ci, converging for C∞
                                                        1. l= bond length
                                                          1. n= number of bond lengths
                                                          2. No correlations between all θij, and all θij allowable
                                                            1. Equivalent FJC
                                                              1. N=L^2/(
                                                                1. L= Contour length
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