WOUND HEALING

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Mind Map by , created over 6 years ago

Bio Med and Pathology Mind Map on WOUND HEALING, created by aahughes on 04/20/2013.

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Created by aahughes over 6 years ago
T-LYMPHOCYTES
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INTRO TO PATHOLOGY
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HORMONES 1
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SMART School Year Goals
Alice ExamTime
History - Medicine through Time
Alice Love
Surgical Technology, Concepts, Unit 5, Wound healing
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Wound healing
Marilyn See
Wound Healing
Olivia McRitchie
WOUND HEALING 2
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NEOPLASIA
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WOUND HEALING
1 WOUND: disruption of normal structure and function
1.1 HEALING: results in restoration and function
2 CONDITIONS REQUIRED FOR HEALING
2.1 Good nutritional status
2.1.1 Good general health, free from systemic disease
2.1.1.1 Good blood supply to provide, nutrition, oxygen and waste removal
2.1.1.1.1 Freedom from contamination of toxins and foreign bodies
2.1.1.1.1.1 Infection, immunosuppression, cancer, reduced blood supply impair healing
3 HEALING BY PRIMARY INTENTION
3.1 Simple, rapid process in a clean skin wound
3.1.1 Damaged edges are in close proximity
3.1.1.1 Damage is minimal
4 3 STAGES IN REPAIR PROCESS:
4.1 INFLAMMATION: haemostasis, platelets aggregate and form fibrin clot
4.1.1 Inflammatory phase, bacteria phagocytosed, clot infiltrated by PMN's
4.1.1.1 Cytokines released, cause migration and division of cells
4.2 PROLIFERATION: fibroblasts enter site
4.2.1 Angiogenisis: new blood vessels form when endothelial cells migrate
4.2.1.1 Collagen deposition and granulation tissue formation:
4.2.1.1.1 Fibroblasts lay down collagen matrix
4.2.1.1.1.1 Granulation tissue consist of new blood vessels+inflam cells
4.2.1.1.1.1.1 Epithelialisation:, e cells migrate to wound edges
4.2.1.1.1.1.1.1 Contraction: Myofibroblasts make wound smaller by contracting
4.3 MATURATION AND REMODELLING
4.3.1 Granulation tissue replaced by fibrous scar
4.3.1.1 arranging of collagen fibres for strenght
4.3.1.1.1 vascularity reduces, cells removed by apoptosis

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