Describe the double circulation as a low pressure flow
to the lungs and a high pressure flow to the body
tissues and relate to the functions of the two circuits
Circulatory system
the organ system made up of blood vessels and the
heart that transports blood. Mammals have a double
circulation with blood passing through the heart twice
in one circuit of the body
Describe the strucure of the heart to
include muscular walls, septum and valves
The heart consists almost entirely of cardiac muscle.
The left and right side of the heart are divided by the
septum, a wall of tissue, which prevents
deoxygenated blood on the right side mixing with
oxygenated blood on the left side. Between each
atrium and ventricle is a valve, which prevent blood
flowing back (backflow).
Describe the heart as a pump for the
flow of blood and the role of valves to
permit only one-way flow
the ventricles have more muscular walls than the atria because
they have to pump the blood much further than the atria - either
to the lungs or to the tissues of the rest of the body.
the pressure of blood against the
valves make them open to let the
blood pass through, but they close
when blood flows back to fill the
pockets, so as to prevent backflow.
State the sequence of events that
take place during one heart beat
Diastole is when the heart
muscles are relaxed. Blood flows
into the atria from the veins.
Systole is when the
heart muscles contract.
The atia contract and force blood into
the ventricles. The valves between the
atria and ventricles open. Then the
ventricles contract to force blood out
into the arteries. The valves close.
the right ventricle pumps
blood to the lungs in the
pulmonary artery.
the left ventricle pumps
blood to the rest of the
body in the aorta.
deoxygentated blood returns to the
right atrium in the vena cava.
oxygenated blood returns to the left
atrium in the pulmonary veins.
Name the main blood vessels to and
from the heart, lungs, liver and kidney
To
heart
right atrium: vena cava.
left atrium: pulmonary vein
lungs
pulmonary artery
liver
hepatic artery,
hepatic portal vein
kidney
renal artery
From
heart
right ventricle: pulmonary artery.
left ventricle: aorta
lungs
pulmonary vein
liver
hepatic vein
kidney
renal vein
Describe the structure and function
of arteries, veins and capillaries
Structure
arteries
narrow space in centre. walls: thick
and muscular with elastic fibres.
veins
wider space in centre. walls: less muscular
and less elastic. has semi-lunar valves
capillaries
are very narrow,
walls: one cell thick
Function
arteries
the main blood vessel, carries blood
which then branches into capillaries
veins
carries deoxygenated blood away from organ(s)
through heart to lungs to be oxygenated again
capillaries
carries blood. oxygen, carbon dioxide and dissolved food
substances diffuse through wall to and from blood (cells)
Explain how the structure of
arteries, veins and capillaries
adapts them to their functions
arteries
thick muscular walls help to withstand pressure.
elastic fibres help to push blood along.
veins
much less pressure than in arteries. less elastic walls - pressure
from body muscles and other surrounding organs help to move
blood along. valves also help maintain a one-way flow of blood.
capillaries
one cell thick walls help with diffusion.
Describe how to investigate
the effect of physical activity
on pulse rate
measure pulse rate at rest (two
fingers at throat) for 1 minute. do
light exercise for 1 minute.
measure pulse rate for 1 minute
again. do heavy exercise for 3
mins. measure pulse rate for 1
minute again... etc.
physical activity increases pulse rate,
supplying muscles with more oxygen and
glucose and removing carbon dioxide
quicker.
Describe coronary heart
disease in terms of blockage
of coronary arteries
the heart needs glucose and oxygen to keep the muscles
working. glucose and oxygen are transported to the heart in
the coronary arteries. if these arteries get blocked then the
heart muscle could become starved of oxygen and die.
cholesterol (made in the liver) can stick to artery
walls, narrowing the artery and slowing down the
flow of blood - this is called artherosclerosis.
State the possible causes
of coronary heart disease
and ways to prevent it
Causes
eating a diet with too
much saturated fat
(increases
concentration of
cholesterol in blood)
being over-weight
smoking
taking little or
no exercise
stress
Ways to prevent it
take care of
your diet - eat a
balanced diet
take regular exercise
don't smoke
List the main components of blood
plasma, white blood cells,
platelets, red blood cells
Identify red and white blood
cells in diagrams, photographs
and under the microscope
red blood cells
have no nuclei, are red (because of
the red pigment haemoglobin)
white blood cells
have nuclei, are colourless under a
microscope, there are two types:
phagocytes and lymphocytes
Describe the role of red blood cells
and haemoglobin in oxygen transport
because red blood cells have no nuclei, this leaves more
space for haemoglobin (found in cytoplasm) that combines
with oxygen to form oxyhaemoglobin. red blood cells carry
the oxygen in haemoglobin to cells around the body.
Describe the functions of
plasma in transport
plasma is 55% of blood volume
and consists of and transports:
nutrients such as glucose,
amino acids, lipids,
vitamins and mineral ions
wastes such as urea
and carbon dioxide
blood proteins
such as albumen
and antibodies
hormones such as
insulin, glucagon
and adrenaline
Describe the process
of blood clotting
Describe how white blood cells such
as lymphocytes and phagocytes
protect the body from disease
phagocytes ingest pathogens,
such as bacteria - they surround
pathogens, ingest them, take
them into food vacuoles, digest
them using enzymes.
phagocytes can move through
capillary walls as well. - this
process is called phagocytosis
lymphocytes recognise 'foreign'
bacterium or virus and make
proteins called antibodies which
attack the pathogens in a
number of ways: make them
stick together (agglutinate),
dissolve their membranes,
neutralise the toxins that some
pathogens, such as bacteria,
produce.
Describe the roles of the immune
system in antibody production,
tissue rejection and phagocytosis
antibody production
there is a different type of
antibody for each type of
pathogen. after you have had a
disease, lymphocytes are ready
to produce more of the
appropriate antibodies should
the pathogen enter the body
again - this makes you immune
to thay particular disease.
phagocytosis
phagoctyes ingest
and kill pathogens
tissue rejection
drugs are given to patient to
supress immune system and
the bone marrow is treated
with radiation to stop white
blood cell production for a
period of time
Describe the exchange of materials
between capillaries and tissue fluid
State that platelets cause blood to clot
Describe the functions of the lymphatic system in
circulating lymph and producing lymphocytes
Describe the one-way flow of blood
around the body through the pulmonary
(lungs) and systemic (rest of body) circuits
the one-way flow of blood, means that the heart pumps
blood, giving it pressure, so that it flows inside the arteries
around the body. the pulmonary and the systemic circuits
are part of the one-way flow of blood/ double circulation