8624272
Description
Mind Map by sarah hammoodi, updated more than 1 year ago
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Created by sarah hammoodi
about 7 years ago
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Ahmad Cannot
Run
- Causes of
Muscle
Weakness
- Infection
- poliovirus > poliomylitis
Lyme disease
- poliovirus > poliomylitis
Lyme disease
- Neurological
- Demyelinating disorders:
Guillain-Barré syndrome
- Demyelinating disorders:
Guillain-Barré syndrome
- Medications
- Statin> atorvastatin (Lipitor)
Amiodarone (oral route)
- Statin> atorvastatin (Lipitor)
Amiodarone (oral route)
- Electrolyte
- Hyperkalemia
- Hyperkalemia
- Genetics
- Metabolic
- Glycogenoses: Acid maltase
deficiency
- Glycogenoses: Acid maltase
deficiency
- Infection
- Nutrients and Muscle
Development
- Calcium
Iron
Vitamin D
Vitamin B12
Magnesium
Zinc
- Calcium
Iron
Vitamin D
Vitamin B12
Magnesium
Zinc
- Physical Examination
- Muscle Strength Scale
- Introduction & Consent HEPA
Inspection SSSP Palpation:
Skin Temperature Joints
Tendons Ligaments
- Move
- Dorsiflexion Plantar
Flexion Inversion
Eversion Flexion of
great toe
- Dorsiflexion Plantar
Flexion Inversion
Eversion Flexion of
great toe
- Special Test
- Inversion and Eversion stress test
Thompson’s test for tendoachillies
rupture Tests for Morton’s
metatarsalgia
- Inversion and Eversion stress test
Thompson’s test for tendoachillies
rupture Tests for Morton’s
metatarsalgia
- pes cavus(high arch)
- fixed plantar flexion of the foot. A
high arch is the opposite of a flat
foot and is somewhat less common
- fixed plantar flexion of the foot. A
high arch is the opposite of a flat
foot and is somewhat less common
- Muscle Strength Scale
- Gait
- Gait Cycle
- abnormal gait
- Trendelenburg gait
- waddling (duck) gait.
- Anterior trunk bending
- inadequacy of the knee
extensors.
- inadequacy of the knee
extensors.
- Posterior trunk bending
- inadequacy of
hip extensors.
- inadequacy of
hip extensors.
- Swing-out
- presence of weak hip flexors
- presence of weak hip flexors
- Steppage gait
- inadequate dorsiflexion control
- inadequate dorsiflexion control
- Vaulting
- Going up on the toes of the
stance phase leg.
- Going up on the toes of the
stance phase leg.
- Antalgic gait
- as short a time is possible is
spent on the painful limb, and
a correspondingly longer time
is spent on the pain-free side.
- as short a time is possible is
spent on the painful limb, and
a correspondingly longer time
is spent on the pain-free side.
- Trendelenburg gait
- Gait Cycle
- Duchene Muscular Dystrophy
- DMD Gene
- Xp21 2.2
megabases
79 exons 8
promoters
- mutation
- Xp21 2.2
megabases
79 exons 8
promoters
- dystrophin
- Dystrophin provides strength to muscle
cells by linking the internal cytoskeleton to
the surface membrane.
- Dystrophin provides strength to muscle
cells by linking the internal cytoskeleton to
the surface membrane.
- Genetic
Difference
Between DMD &
BMD
- complication
- X-linked inherited
- Investigations
- Serum Creatine Kinase
- A high CK generally indicates that
there has been some recent muscle
damage but will not indicate its
location or cause.
- A high CK generally indicates that
there has been some recent muscle
damage but will not indicate its
location or cause.
- Electromyography
- EMG results can reveal nerve dysfunction,
muscle dysfunction or problems with
nerve-to-muscle signal transmission.
- EMG results can reveal nerve dysfunction,
muscle dysfunction or problems with
nerve-to-muscle signal transmission.
- Thyroid Function Test
- Western Blot
- The separation of proteins by electrophoresis, then The binding of
specific antibody to the protein of interest.
- The separation of proteins by electrophoresis, then The binding of
specific antibody to the protein of interest.
- Muscle Biopsy
- Cross section of muscle
shows extensive
replacement of muscle
fibers by fat cells.
- Cross section of muscle
shows extensive
replacement of muscle
fibers by fat cells.
- Serum Creatine Kinase
- MANAGEMENT
- Physical and occupational therapy
- PHARAMACOLOGICAL
- Steroids Prednisone
Deflazacort -Creatine
monohydrate
supplementation
- Steroids Prednisone
Deflazacort -Creatine
monohydrate
supplementation
- -Gene therapy:
- -Stem cell
- Physical and occupational therapy
- Prognosis
- death occurs usually at
about 18-20yrs of age.
- death occurs usually at
about 18-20yrs of age.
- DMD Gene
- Anatomy of the foot
- foot and ankle
bones
- foot ligaments
- arterial supply
- nerve supply
- layers of the sole
- cutaneous nerve supply
- foot and ankle
bones
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