Biological Ageing LC 3.2 - created from Mind Map

Page 1

minimun death at the late teens

Evolution of ageing

Significant amount of energy spent on maintainence

Ageing process

Damage

Multiple mechanisms which cause ageing

ageing is not a genetic program

Selection shadow

Ageing caused by damage of the body

Natural selection does not occur on older organisms as they would have already died

Regulated by a number of random mechanisms

Random damage

accumulation of cellular defects

Functional impairment of organs and tissue leading to age related disease and disability

O2

DNA replication

Mitochondria mutations accumulate

Damaged proteins

Respiration forms free radicals

Damage cell DNA and mitochondria DNA

Increased frequency of mutations as we age

less ATP produced

aggregate and forn plauques and tangles

common in neurological diseases

Page 2