Basal Ganglia Pathways

Tosin O
Note by Tosin O, updated more than 1 year ago
Tosin O
Created by Tosin O over 5 years ago
21
1

Description

Indirect and Direct Basal Ganglia Pathways

Resource summary

Page 1

Direct Pathway = Disinhibition of the ThalamusMotor Cortex excites the Striatum (cauduate nucleus and putamen)Leads to inhibitory signals to the Globus pallidus internal Also leads to inhibitory signals to the Substantia Nigra pars reticulata/reticularisIn the mean time, Substantia Nigra pars compacta = dopaminergic signalling to Striatum via D1 receptorsFurther enhances Inhibitory signal of Striatum and Pars reticulataVA/VL nuclei of Thalamus = excited = talks back to cortexUltimately resulting in Muscle movement

Page 2

Indirect Pathway = Dampening down signal (less movement = fine-tuning to prevent overstimulation probably)Motor Cortex excites the Striatum (cauduate nucleus and putamen)Leads to inhibitory signals to the Globus pallidus externalLeads to disinhibition of Subthalamic nucleiSubthalamic Nucleus = excites Pars reticulata and globus pallidus internal Leads to inhibition of Thalamus = lowers output = less movementIn the mean time, Pars compacta = dopamine signalling via D2 receptors to enhance inhibition of globus pallidus externa

Show full summary Hide full summary

Similar

Drug absorption, distribution, metabolism and excretion
Hannah Tribe
Exam 1 Medications
tera_alise
Pharmacology
Justin Veazey
Monoamine pharmacology -Antidepressant drugs - Dr. Emma Robinson
Anna mph
NCLEX REVIEW MODEL
Jamie R Pascual
Cognition and Dementia - Alzheimer's disease.
Anna mph
General Anaesthetics Part 1 - Steve Fitzjohn
Anna mph
Transcription
Has Maj
Module 6 chapter 12.
Alannah Mendoza
Drug molecules - properties and actions & functional groups
Alyssa B
Organelles
Has Maj