Flashcards
Ageing Brain
Flashcards do conjunto (16)
- 1Patridge (2014)Ageing is co-morbid to cardiovascular disease, dementia, cancer, diabetes
- 2McCay (1935)The first to show that the ageing process can be slowed down
Reduce calorie intake by 20% in rodents = decrease ageing by 20% - 3Patridge (2010)Found the same results as McCay but in primates
- 4Partridge (2014)Reducing IIS + TOR pathway activity = increase in lifespan and health in a variety of species
- 5Cohen et al. (2009)Reducing IIS pathway activity in a mouse model of Alzheimers reduced behavioural symptoms and biomarkers in the brain of the disease
- 6Ornish et al. (2013)Lifestyle changes can increase telomere length in cancer patients
- 7Early Embryonic Development (Z, C, B, M, B, G)Zygote, cleavage, blastomere, morula, blastocyst (blastula), gastrula
- 8Neural Tube DevelopmentPlate, Groove, Tube
- 9Kitada & Dezawa (2012)Stem cells could have a therapeutic potential for Parkinson's Disease: neural stem cells and embryonic stem cells - can protect damages tissues and can generate into dopamine neurones
- 10Yamasaki et al. (2007)Stem cells therapeutic potential for Alzheimer's Disease: neural stem cells transplanted into brain of transgenic mouse model survive, migrate, differentiate and improve memory
- 11Dodd, Jessel & Placzek (1998)The neural plate is induced by the notochord, floor plate and roof plate of the mesodermal layer
- 12Ulloa & Marti (2009)Wnt & Sonic Hedgehog are the main transcription factors in the mesoderm
- 13Herrup & Stuer (1999)Radial glial cell act like a ladder in cell migration
- 14Inside-first, outside-last layeringCells leaving later migrate past the older neurons to the outermost cortex
- 15Fazeli & Walsh (1996)Aggregation is guided by cell-adhesion molecules located on the surface of the cells + bind to molecules on other cells
- 16What are the 3 hypotheses of axon growth?Chemoaffinity, blueprint and topographic gradient
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- Ageing Brain (PS3061) FlashCards sobre Ageing Brain, criado por Eleni Blakemore em 11-04-2017.
- Criado por
- Eleni Blakemore
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