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100974
Biological
Descrição
Psychology (Schizophrenia) Mapa Mental sobre Biological, criado por lucysavage176 em 21-05-2013.
Sem etiquetas
psychology
schizophrenia
psychology
schizophrenia
Mapa Mental por
lucysavage176
, atualizado more than 1 year ago
Mais
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Criado por
lucysavage176
quase 11 anos atrás
81
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0
Resumo de Recurso
Biological
Family studies
1st degree relatives
share 50%
18x more at risk
Kendler
inconclusive
retrospective
support
Kety
mothers with + without scizo
matched pairs
group 1- diagnosed 16.2%
gruop 2- 1.9%
evaluation
not rely on retrospective data
memory
genes vs environment
reliablility of diagnosis
others diagnosed on old system
Twin studies
MZ 40%
DZ 5.3%
maudsly twin register
share womb
Adoption studies
Finnish
Tienari
112 schizo mothers
7% developed schizo
153 control
1.5%
separated before age 4
poor communication in adopted families increaded risk
Biochemical
dopamine
limbic system
excess dopamine
super-sensitivity
scizo was induced in rats using amphetamines
evaluation
post mortems
increase dopamine/receptor density
not just scizo
not only factor
PET scans
causal?
drugs
aleviate posative not negative symptoms
most effective drugs affect serotonin
Diathesis stress
predisposition
trigger
genetics cannot give full explaination
89% have no known relative with schizo
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