Mapa mental
Axon guidance
Conteúdo do mapa
Axon guidance
Weiss hypothesis- random outgrowth and elimination of non-functional
Sperry hypothesis- specific outgrowth due to chemoaffinity
- usually posterior retina to anterior tectum, vice versa
- experiments where posterior (temporal) retina removed, anterior (nasal) grew directly to posterior tectum
- REGENERATION NOT DEVELOPMENT!
- experiments where posterior (temporal) retina removed, anterior (nasal) grew directly to posterior tectum
- usually posterior retina to anterior tectum, vice versa
DEVELOPMENT!
- Highly stereotyped, find way to target due to guidance cues
- Pioneering axons, pathway for developing axons to follow
- If removed then axon growth stunted despite presence of other axons
- Therefore releases specific cues!!!
- LABELLED_PATHWAY HYPOTHESIS
- selective fasciculation of axons with other axons
- LABELLED_PATHWAY HYPOTHESIS
Informações
- Descrição
- Mapa Mental sobre Axon guidance, criado por ally2981 em 22-01-2015.
- Criado por
- ally2981
- Visualizações
- 1
- Avaliação