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Quiz

Chapter 5: Pharmacodynamics

Usuário eliminado 14 perguntas Atualizado em 23 abr 2018

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Perguntas do quiz (14)

  1. 1What is the most accurate definition of pharmacodynamics?
    1. AHow a medicine changes the body
    2. BHow the body handles medication
    3. CHow the body removes drugs
    4. DHow the body changes the drug
  2. 2What is a frequency distribution curve?
    1. AA graphical representation of the number of patients responding to a drug action at different doses.
    2. BA graphical representation of the number of patients dying from the drug
    3. CA graphical representation of the number of patients getting side effects from the drug
    4. DA graphical representation of the onset of drug action.
  3. 3The following is information about a frequency distribution curve (since I couldn't find or make a picture I like). Please fill in the blanks.

    A [blank_start]frequency distribution curve[blank_end] is a graphical representation of the number of patients responding to a drug action at different doses. On the [blank_start]Y axis[blank_end] is the number of patients responding; on the [blank_start]X axis[blank_end] is the dose of the medication. The [blank_start]peak[blank_end] of the curve indicates the largest number of patients responding to the drug. The dose in the middle of the curve represents the drug's [blank_start]median effective dose[blank_end], which is the dose required to produce a specific therapeutic response in 50% of a group of patients.

    Nurses should realize that the standard or average dose predicts a therapeutic response for only [blank_start]half[blank_end] of the population. It is not enough to know the average dose; it's important to know when and how to request whether doses should be adjusted.
    1. Afrequency distribution curve
    2. BMedian toxicity dose
    3. CGraded dose response
    4. DY axis
    5. EX axis
    6. Fpeak
    7. Gbottom
    8. Hmedian effective dose
    9. Igraded dose-response
    10. Jhalf
    11. Ka quarter
    12. L3/4
    13. Mmedian lethal dose
  4. 4A drug's median lethal dose is the dose of the drug that will be lethal in 50% of all animals.
    A drug's median effective dose is the amount of the drug required to produce a specific therapeutic response in 50% of a group of patients.
    The therapeutic index is the ratio of a drug's median effective dose to the drugs median lethal dose.

    When the median effective and median lethal doses are close together on a graph (like shown in the picture), what does that say about the drug?    Imagem da pergunta 4
    1. AIt has a narrow safety margin.
    2. BIt has a large therapeutic index
    3. CIt's a safer drug.
    4. DIt would take a very large error to cause a patient to overdose on the drug.
  5. 5The median lethal dose is often determined in clinical trials.
    1. AVerdadeiro
    2. BFalso
  6. 6What does the graded dose response measure?
    1. AThe variability in responses to a drug observed within a single patient.
    2. BThe variability in responses to a drug observed within a population.
    3. CThe variability in responses to a drug observed within a family.
    4. DThe amount of patients getting sick from a drug.
  7. 7The following is information about the graded dose-response relationship and the dose-response curve. Fill in the blanks with the correct information.

    The graded-dose response relationship and the graded-dose response curve observes and measures the patient's [blank_start]response[blank_end] at different [blank_start]doses[blank_end] of the drug. The 3 distinct phases are:

    Phase 1: The [blank_start]flat[blank_end] portion of the curve. It indicates that few target cells have been affected by the drug.
    Phase 2: The [blank_start]straight line[blank_end] portion of the curve. This portion often shows a liner relationship between the [blank_start]amount[blank_end] of drug administered and he [blank_start]degree[blank_end] of response obtained from the patient.
    Phase 3: A [blank_start]plateau[blank_end] is reached in which increase the drug dose produces no additional therapeutic response. This is usually the point in which the drug has reached its [blank_start]maximal response[blank_end], so giving a higher dose will have no effect.     Imagem da pergunta 7
    1. Aresponse
    2. Bdoses
    3. Cflat
    4. Dstraight line
    5. Eamount
    6. Fdegree
    7. Gplateau
    8. Hmaximal response
  8. 8There are 2 fundamental ways to compare medications within therapeutic and pharmacologic classes.

    [blank_start]Potency[blank_end] is how much of a drug is needed to produce a therapeutic effect. Drugs that are more potent will produce a therapeutic effect at a [blank_start]lower[blank_end] dose.
    [blank_start]Efficacy[blank_end] is the [blank_start]magnitude[blank_end] of response that can be produced from a particular drug.

    From a pharmacological perspective, [blank_start]efficacy[blank_end] is the more important value.
    1. APotency
    2. BEfficacy
    3. Clower
    4. Dhigher
    5. EEfficacy
    6. FPotency
    7. Gmagnitude
    8. Hamount
    9. Iefficacy
    10. Jpotency
  9. 9The cellular macromolecule that a drug binds to in order to initiate its effects is called its what?
    1. AReceptor
    2. BProtein
    3. CMessenger
    4. DPort
  10. 10The vast majority of drug receptors are proteins.
    1. AVerdadeiro
    2. BFalso

Informações

Descrição
O usuário eliminou as informações de disciplina Quiz sobre Chapter 5: Pharmacodynamics, criado por Usuário eliminado em 10-04-2018.
Autor
Usuário eliminado
Idioma
English
Visualizações
118
Histórico
Criado em 10 abr 2018 · atualizado em 23 abr 2018

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