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Quiz

Chapter 8: Drug Administration Throughout the Life Spam

Usuário eliminado 28 perguntas Atualizado em 23 abr 2018

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Perguntas do quiz (28)

  1. 1Drug therapy in pregnant women is discontinued unless a serious condition is present.
    1. AVerdadeiro
    2. BFalso
  2. 2Select the drugs that are less likely to cross the placenta in pregnant women..
    1. AWater soluble
    2. BIonized
    3. CBound to plasma proteins
    4. DLipid soluble
    5. ENon-ionized.
    6. FNot bound to plasma proteins
  3. 3Which of the following is NOT a bodily change in pregnant women that can affect the success of drug therapy?
    1. AIncreased progesterone levels.
    2. BIncreased blood volume.
    3. CIncreased blood flow to the kidneys
    4. DAlterations in lipid levels.
    5. EDecreased blood blow to the skin.
  4. 4Fat soluble drugs are distributed into breast milk, so it may be passed to the lactating infant,
    1. AVerdadeiro
    2. BFalso
  5. 5Some drugs, such as thalidomide, are absolute teratogens.
    1. AVerdadeiro
    2. BFalso
  6. 6The following are stages of pregnancy, as they relate to pharmacology. Note that these are out of order.

    [blank_start]Preimplantation phase[blank_end]: This occurs during weeks [blank_start]1-2[blank_end] of the [blank_start]first trimester[blank_end]. The embryo has not yet established a physical connection to the mother. This is also called the [blank_start]all or none[blank_end] period because exposure to a teratogen either causes death or has no effect. Drugs are much [blank_start]less likely[blank_end] to cause malformations because the baby's organ systems have not yet begun to form, but certain drugs (such as [blank_start]nicotine[blank_end]) can cause growth delays.

    [blank_start]Fetal period[blank_end]: Occurs in weeks [blank_start]9-40[blank_end] post-conception. During this time, the fetus' organs systems are growing and developing. Blood flow to the placenta [blank_start]increases[blank_end] and placental vascular membranes become [blank_start]thinner[blank_end]. This maximizes the transfer of substances from mother to child. The fetus may receive [blank_start]larger[blank_end] doses of medications and other substances from the mother, which has a prolonged duration of action in the unborn child due to a lack of mature metabolic enzymes and efficient excretion mechanisms.. Exposure to teratogens is [blank_start]more likely[blank_end] to produce slowed growth or impaired organ function rather than gross structural malformations.

    [blank_start]Embryonic period[blank_end]: This occurs in weeks [blank_start]3-8[blank_end] postconception. There is rapid development of internal structures. This is the period of [blank_start]maximum sensitivity[blank_end] to teratogens. Teratogenic agents can lead to structural abnormalities and spontaneous abortion. The abnormality depends on which organ is forming.
    1. APreimplantation phase
    2. B1-2
    3. Cfirst trimester
    4. Dsecond trimester
    5. Ethird trimester
    6. Fall or none
    7. Gsomething or nothing
    8. Hless likely
    9. Inicotine
    10. Jatorvastatin
    11. Kmetoprolol
    12. LFetal period
    13. M9-40
    14. Nincreases
    15. Odecreases
    16. Pthinner
    17. Qthicker
    18. Rlarger
    19. Ssmaller
    20. Tmore likely
    21. U3-8
    22. Vmaximum sensitivity
    23. Wminimal sensitivity
    24. XEmbryonic period
  7. 7The following is the current FDA pregnancy category ratings with examples. I made them out of order to make sure that we know the answers.

    [blank_start]A[blank_end]- Adequate, well -controlled studies in pregnant women have shown no increased risk of fetal abnormalities in any trimester of pregnancy.

    [blank_start]C[blank_end]- Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in women. OR no animal studies have been conducted and there are no adequate and well controlled studies on women (basically, we don't know what this will do to your baby.)

    [blank_start]X[blank_end]- Adequate, well controlled observational studies in animals or pregnant women have demonstrated evidence of fetal abnormalities or risks.

    [blank_start]D[blank_end]- Adequate, well controlled or observational studies in pregnant women have demonstrated a risk to the fetus.

    [blank_start]B[blank_end]- Animal studies have revealed no evidence of harm to the fetus, but there aren't any adequate and well-controlled studies in pregnant women. OR animal studies have shown an averse effect, but adequate and well-controlled studies in pregnant women have failed to yield a similar response.
    1. AA
    2. BB
    3. CC
    4. DB
    5. EX
    6. FD
    7. GD
    8. HC
    9. IB
    10. JC
    11. KC
    12. LD
    13. MX
    14. NA
    15. OD
    16. PX
    17. QA
    18. RB
    19. SC
    20. TB
    21. UA
    22. VX
    23. WA
    24. XD
    25. YX
  8. 8Select the drugs that are a FDA pregnancy risk category A.

    (Here's a hint: 4 of these are correct)
    1. APrenatal vitamins
    2. BInsulin
    3. CThyroxine
    4. DFolic acid
    5. EPenicillins
    6. FSelective serotonin reuptake inhibitors
    7. GACE inhibitors
    8. HStatins
  9. 9Select the drugs that are an FDA pregnancy risk category B.

    (Here's a hint: 5 of these are correct)
    1. APenicillins
    2. BCephalosporins
    3. CAzithromycin
    4. DAcetaminophen
    5. EIbuprofin
    6. FThyroxine
    7. GClarithromycin
    8. HGentamycin
    9. ILithium carbonate
    10. JWarfarin
  10. 10Select the drugs that are a FDA pregnancy risk category C.

    (Hint: 6 of these are right).
    1. AClarithromycin
    2. BFluoroquinolones
    3. CBactrim
    4. DSelective serotonin reuptake inhibitors
    5. ECorticosteroids
    6. FAntihypertensives
    7. GCarbamazepine
    8. HCephalosporins
    9. IValporic acid
    10. JClomiphene

Informações

Descrição
O usuário eliminou as informações de disciplina Quiz sobre Chapter 8: Drug Administration Throughout the Life Spam, criado por Usuário eliminado em 16-04-2018.
Autor
Usuário eliminado
Idioma
English
Visualizações
42
Histórico
Criado em 16 abr 2018 · atualizado em 23 abr 2018

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