Independent and Supplementary Prescribing

Choose the word or phrase from the list below that best completes this sentence. Pharmacokinetics can be described as ________________________

Choose the word or phrase from the list below that best completes this sentence. Drugs may act locally or systemically. Systemically means that the drug must enter ___________________ in order to be delivered to its site of action.

Which equation can you use to calculate the amount of a drug that reaches the systemic circulation?

Choose the word or phrase from the list below that best completes this sentence. Drugs administered as an IV injection have a bioavailability of _________.

What words make up the acronym ADME?

Choose the word or phrase from the list below that best completes this sentence. Generally in absorption, drugs move from an area of high concentration to a low concentration via ______________

Choose the word or phrase from the list below that best completes this sentence. When drugs are being absorbed from an area of their low concentration to a higher concentration, they move by _____________

Choose the word or phrase from the list below that best completes this sentence. Cell membranes are composed of a double layer of ____________________

Water soluble drugs pass cell membranes easier than lipid soluble drugs.

Choose the word or phrase from the list below that best completes this sentence. The more _______________ a drug, the easier it is for the drug to be absorbed from the small intestine into the circulation.

Un-ionised drugs are lipid soluble. What does un-ionised mean?

Choose the word or phrase from the list below that best completes this sentence. The small intestine has a large surface area due to it's large number of __________.

Choose the word or phrase from the list below that best completes this sentence. The larger the surface area for drug absorption, the _______ the absorption.

Where does most drug absorption take place?

The presence of food after a meal will slow gastric emptying.

Sometimes drugs are prescribed to be taken with food. Why might this be?

Choose the word or phrase from the list below that best completes this sentence. Some drugs are absorbed from the small intestine into the _____________ and are transported directly into the liver.

What is the name of the process by which a drug is fully or partially metabolised by the liver, before entering the systemic circulation?

Hypomotility of the GI tract may result in lower concentrations of drug entering the circulation.

Blood flow affects absorption.

Choose the word or phrase from the list below that best completes this sentence. A drug must reach it's site of action in ______________, in order to exert it's effect.

Blood flow affects distribution.

Blood flow affects distribution. Organs that have high perfusion, e.g. heart, therefore receive drugs slowly.

Choose the word or phrase from the list below that best completes this sentence. Only ________ drug can cross plasma membranes and therefore exert an effect.