BioChemistry Quiz

Descrição

Get ready to get Rekt.
Roy Hove
Quiz por Roy Hove, atualizado more than 1 year ago
Roy Hove
Criado por Roy Hove quase 8 anos atrás
61
1

Resumo de Recurso

Questão 1

Questão
L’acide phosphorique est tri-basique, avec des valeurs de pKa de 2.14, 6.88 et 12.4. Quelle forme ionique est prédominante à pH = 5.9 ?
Responda
  • H3PO4
  • H2PO4-
  • HPO42-
  • PO43-

Questão 2

Questão
What is the basic formula of Carbohydrates?
Responda
  • Cn(OH)n
  • Cn(CO2)n
  • Cn(H2O)n
  • C(H2O)n

Questão 3

Questão
Which of these is not these is not a polysaccharide?
Responda
  • Cellulose
  • Glycogen
  • Starch
  • Fructose

Questão 4

Questão
Long chains of single sugars covalently linked describes what types of carbohydrates?
Responda
  • Oligosaccharides
  • Multisaccharides
  • Polysaccharides
  • Megasaccharides

Questão 5

Questão
Which pair of molecules are epimers?
Responda
  • D-Glucose and D-Galactose
  • D-Glucose and L-Glucose
  • Threose and Erythrose
  • D-Glucose and D-Gulose

Questão 6

Questão
Which of these structures is glucose?

Questão 7

Questão
Galactose is a ___ epimer of glucose.
Responda
  • C1
  • C2
  • C3
  • C4

Questão 8

Questão
Which one of these is a ketohexose
Responda
  • Fructose
  • Glucose
  • Ribose
  • 2-Deoxy-Ribose

Questão 9

Questão
Which of these is not true?
Responda
  • Enantiomers are stereoisomers that are not mirror images
  • In sugars that contain the most chiral centers only the one that is the most distant from the caronyl carbon is designated as D or L
  • hemiacetals are formed by alcohols attacking aldehydes
  • Alcohol oxygen atom is nucleophilic

Questão 10

Questão
During the cyclisation of Monosaccharides which is/are true?
Responda
  • The carbon atom furthest from the former carbonyl atom becomes the anomeric carbon
  • The position of anomeric carbon's oxygen determines whether the anomer is α or β
  • The position of the anomeric carbon's hydroxyl group determines whether the anomer is α or β
  • The carbon atom furthest from the former carbonyl atom becomes the chiral center

Questão 11

Questão
Which of these are carbohydrates that have a chemical structure that includes a six-membered ring consisting of five carbon atoms and one oxygen atom?
Responda
  • Furanoses
  • Pyranoses

Questão 12

Questão
The disaccharide formed upon condesation of two glucose molecules via the 1-4 bond is called
Responda
  • Trehalose
  • Sucrose
  • Maltose
  • Lactose

Questão 13

Questão
Which of these describes cellobiose
Responda
  • α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside
  • β-D-glucopyranosyl-(1→4)-β-D-glucopyranose
  • β-D-galactopyranosyl-(1→4)-α-D-glucopyranose
  • α-D-glucopyranosyl-(1→4)-β-D-glucopyranose

Questão 14

Questão
Polysaccharides...
Responda
  • can be branched but cannot have multiple monomer types
  • cannot be unbrached
  • have defined molecular weights
  • with only two monomer types cannot be branched

Questão 15

Questão
Which one of these hetero-polysaccharides has the largest size
Responda
  • peptidoglycan
  • agarose
  • hyaluronan

Questão 16

Questão
which of these is used in Algae cell walls
Responda
  • Peptidoglycan
  • hyaluronan
  • agarose

Questão 17

Questão
Glucose is stored in animals as
Responda
  • Glucagon
  • Glycogen
  • Glucose
  • Insulin
  • Starch

Questão 18

Questão
Glycogen is a polysaccharide in which glucose is joined by β-(1→4) linkages
Responda
  • True
  • False

Questão 19

Questão
Glycogen is a polysaccharide in which glucose is joined by α-(1→6) linkages
Responda
  • True
  • False

Questão 20

Questão
Which of the following is true
Responda
  • Amylose is the branched form of starch
  • α-amylase is a pancreatic enzyme that hydrolyses the α (1→4) linkages of starch
  • Glycogen has less α (1→4) linkages than starch
  • Glycogen has less α (1→6) linkages than starch

Questão 21

Questão
hydrolysis of cotton occurs
Responda
  • at the β (1→2) linkages of D-glucose
  • at the α (1→2) linkages of D-glucose
  • at the β (1→4) linkages of D-glucose
  • at the α (1→4) linkages of D-glucose

Questão 22

Questão
Which of the following is not true
Responda
  • Glycosidic bonds can freely rotate
  • more than 10^9 metric tonnes of cotton are produced/year
  • Starch can be coiled into a helical structure
  • Glycogen and amylopectin have only one reducing end

Questão 23

Questão
Which of these lack enzymes that can hydrolyse D-glucose β (1→4) linkages
Responda
  • Fungi
  • bacteria
  • termites
  • protozoa

Questão 24

Questão
Chitin
Responda
  • is a heteropolymer
  • consists of β (1→2) linkages of N-acetyl-D-glucosamine
  • is insoluble
  • once acetlated forms Chitosan

Questão 25

Questão
Sephadex gels separate proteins by
Responda
  • size
  • charge
  • polarity
  • shape

Questão 26

Questão
Which of these would you find in the first fractions after size exclusion chromatography
Responda
  • acidic proteins
  • the smallest proteins
  • the largest proteins
  • basic proteins

Questão 27

Questão
which of these are homoglycans
Responda
  • Agar
  • Dextrans
  • Peptidoglycan
  • None

Questão 28

Questão
Which of these can be linked to epichlorohydrin in sephadex beaded gels
Responda
  • Agar
  • Agarose
  • Peptidoglycan
  • Dextran

Questão 29

Questão
Agar is a complex mixture of heteropolysaccharides containing modified
Responda
  • Glucose units
  • Mannose units
  • Fructose units
  • None of the above

Questão 30

Questão
Which of these is false
Responda
  • Agarose can be used for growing bacteria
  • Agarose is a component of bacterial cell walls
  • Agarose can be used for DNA separation
  • Agar is a component of seaweed cell walls

Questão 31

Questão
N-acetyl-galactosamine is a ___ epimer of N-acetyl-glucosamine
Responda
  • C3
  • C2
  • C4
  • C6

Questão 32

Questão
Where wold yo expect to find hyaluronate
Responda
  • ECM of Cartilage
  • Hair
  • Nails
  • Horns

Questão 33

Questão
Which one of these glycosaminoglycans acts as a lubricant?
Responda
  • Chondrotin-4-sulfate
  • keratan sulfate
  • heparin
  • hyaluronate

Questão 34

Questão
which one of the has approximately 50'000 disaccharides per chain
Responda
  • hyaluronate
  • keratan sulfate
  • heparin
  • chondrotin-4-sulfate

Questão 35

Questão
Which one of these glycosaminoglycans consists of [galactose β(1,4) Glc-NAc6S] repeating disaccharides
Responda
  • hyaluronate
  • chondrotin-4-sulfate
  • heparin
  • keratan sulfate

Questão 36

Questão
Which of these repeating disaccharides make dermantan sulfate?
Responda
  • glucaronic acid and N-acetylglucosamine
  • glucaronic acid and N-acetylgalctosamine-4-sulfate
  • Iduronic acid and N-acetylgalactosamine-4-sulfate
  • Iduronic acid and N-acetylglucosamine

Questão 37

Questão
The cabohydrate attached to a protein in a Glycoconjugate attaches via...
Responda
  • The C6 carbon
  • The anomeric carbon
  • The furthest carbon from the anomeric carbon
  • The C2 carbon

Questão 38

Questão
Which of the following most likely contains the most glycosylated proteins (Glycoproteins)
Responda
  • Humans
  • E.coli
  • Ebola virus
  • Cats

Questão 39

Questão
O linked oligosaccharides are linked through the N terminus of the amino acid
Responda
  • True
  • False

Questão 40

Questão
In glycoproteins, sugars are attached either to the amide nitrogen atom in the side chain of asparagine (termed an N-linkage) or to the oxygen atom in the side chain of serine or threonine (termed an O-linkage)
Responda
  • True
  • False

Questão 41

Questão
Glycophorin A is the most important attachment site for which of the following parasites in order to enter erythrocytes
Responda
  • Plasmodium falciparum
  • Chilomastix mesnili
  • Entamoeba coli
  • Entamoeba dispar

Questão 42

Questão
Which of these sulfated glycosaminoglycans are attached to a protein anchored to a membrane lipid?
Responda
  • syndecans
  • glypicans

Questão 43

Questão
NB! Select all which are functions of polysaccharides
Responda
  • Labelling of proteins for destruction
  • Recognition sites for growth factors
  • recognition sites for bacteria
  • localization of certain proteins

Questão 44

Questão
Which one of these is not a main component of the extracellular matrix (ECM)
Responda
  • Proteoglycan aggregates
  • Collagen fibers
  • Elastin
  • Fatty acids

Questão 45

Questão
Which one of these in not a characteristic of Glycosaminoglycans
Responda
  • Negatively charged
  • C5 oxidation
  • one monomer is either N-acetyl-glucosamine or N-acetyl-galactosmine
  • found in connective tissue

Questão 46

Questão
Plasmodium flaciparum requires which of these as an attachment site to enter erythrocytes
Responda
  • Glycophorin A
  • Hyaluronan
  • syndecan
  • Podocalyxin

Questão 47

Questão
Which of these about proteoglycans is not true
Responda
  • Proteoglycan aggregates are found in articula cartilage
  • Proteoglycans influence growth factor activation and adhesion
  • glycosaminoglycans are linked to the core protein from the anomeric carbon
  • proteoglycanaggregates form high friction material

Questão 48

Questão
Which of these are integral receptors for extracellular proteoglycans
Responda
  • Integrins
  • actin
  • collagen fibers
  • elastin

Questão 49

Questão
Which of these about enzymatic reactions is true
Responda
  • Enzymes directly affect equilibrium (∆G)
  • Entropy cost is paid during binding
  • enzymes increse reaction rates (κ ) by increasing (∆G)
  • slow reactions do not have high activtaion barriers

Questão 50

Questão
Rate of enzymatic reactions are affected by....? (Click all true)
Responda
  • concentration of enzyme
  • concentration of substrate
  • temperature
  • shape of enzyme
  • shape of substrate

Questão 51

Questão
Which one of these describes a micelle
Responda
  • individual units are wedge shaped
  • artificial carriers of molecules
  • individual units are cylindrical
  • composed lipid-based structures that form pliable sheets

Questão 52

Questão
Which of these is false
Responda
  • membranes vary from 3-10nm
  • membranes form spontaneously by noncovalent forces
  • membranes are symmetric
  • membranes can be found within cells

Questão 53

Questão
Which of these is true about fatty acids
Responda
  • Most natural fatty acids are branched
  • Saturated fatty acids have double bonds between carbons in the chain
  • Most natural fatty acids have an even number of C's
  • linoleic acid is a saturated fatty acid

Questão 54

Questão
Which of these is false about fatty acids
Responda
  • Fatty acids solubility decreases as the chain length increases
  • Melting point decrases as the chain length decreses
  • Melting point increases as the number of double bonds increases
  • unsaturated cis fatty acids have a lower melting point than saturated fatty acids

Questão 55

Questão
Omega-3 (ω-3) fatty acids have
Responda
  • a double bond between the 2nd and 3th carbon from the methyl end of the chain.
  • a double bond between the 3rd and 4th carbon from the methyl end of the chain.
  • a double bond between the 1st and 2nd carbon from the methyl end of the chain.
  • a double bond between the 2nd and 3nd as well as 3rd and 4th carbon from the methyl end of the chain.

Questão 56

Questão
Which of these is untrue
Responda
  • Triacylglycerols are polar
  • Triacylglycerols are non hydrated
  • Vegetable oils are composed of triacylglycerols with unsaturated fatty acids
  • Animal fats are composed of triacylglycerols with saturated fatty acids

Questão 57

Questão
which of these is a greasy solid at room tempreature
Responda
  • triacylglycerols with unsaturated fatty acids
  • triacylglycerols with saturated fatty acids

Questão 58

Questão
which of these is a sphingolipid

Questão 59

Questão
Which of these is the head group of phosphatidylserine

Questão 60

Questão
Which of these has a net charge of -4 at pH7
Responda
  • phosphatidylcholine
  • cardilipin
  • phosphatidylglycerol
  • phosphatidylinositol 4,5- biphosphate

Questão 61

Questão
Which of these is the major component of most eukaryotic cell membranes
Responda
  • phophatidylcholine
  • phosphatidylglycerol
  • cardiolipin
  • phosphatidylethanolamine

Questão 62

Questão
a fatty acid is joined to sphingosine via an
Responda
  • ester linkage
  • amide linkage
  • glycosidic linkage
  • phosphodiester linkage

Questão 63

Questão
ganglioside GM2 has which of these as a head group
Responda
  • glucose
  • galactose
  • di, tri, or tetrasaccharide
  • complex oligosaccharide

Questão 64

Questão
The blood groups are determined in part by the
Responda
  • type of sugars located on the head groups in glycosphingolipids
  • type of sugars located on the head groups in glycolipids
  • type of sphingolipids
  • type of galactolipids

Questão 65

Questão
The structure of sugars located on the head groups in glycosphingolipids is determined by an expression of specific glycosyltransferases. Individuals with a glycosyltransferase that transfers an N-acetylgalactosamine group will
Responda
  • will have the O antigen
  • A blood group
  • B blood group
  • AB blood group

Questão 66

Questão
which of thes is false
Responda
  • Cholesterol modulates cell membrane fluidity
  • Mammals can not synthesize cholesterol
  • cholesterol in loe density lipoproteins tend to deposit in arteries
  • most bacteria lack sterols

Questão 67

Questão
which of these polyketides is an antibiotic
Responda
  • erythromycin
  • amphotericin B
  • lovastatin

Questão 68

Questão
which of these lipids are hormone precursors
Responda
  • vitamins E and K
  • vitamins A and D
  • steroid hormones
  • eicosanoids

Questão 69

Questão
which of these lipids are paracrine hormones
Responda
  • phosphatidylinositols
  • vitamins A and D
  • vitamins E and K
  • Dienes
  • eicosanoids

Questão 70

Questão
which of these is true
Responda
  • cholesterol is predominant in mitochondrial membranes
  • galactolipids are abundant in animals
  • membranes have non-selective import and export across the membrane
  • archaebacteria have monolayer instead of a bilayer

Questão 71

Questão
which of these is a type 6 integral membrane protein

Questão 72

Questão
Which of these amino acid residues would you find predominantly in the transmembrane segments of membrane proteins
Responda
  • Tyr
  • Thr
  • Ser
  • Pro

Questão 73

Questão
Proteins can be targeted to the INNER leaflet of the plasma membrane by farnesylation. The primary sequence of the protein contains a signature for farnesylation which is
Responda
  • CaaX
  • MaaX
  • CaX
  • MaX

Questão 74

Questão
hutchinson-gilford progeria syndrome is caused by
Responda
  • palmitoylation defect
  • myristoylation defect
  • farnesylation defect

Questão 75

Questão
which of these are only found on the outside of cell membranes
Responda
  • proteins
  • lipids
  • carbohydrates

Questão 76

Questão
which of these statements about the physical properties of membranes is true
Responda
  • Permeable to large polar solutes and ions
  • Not permeable to small polar solutes and nonpolar compounds
  • Permeability can be artificially increased by chemical treatment
  • Exist in a single phase and cannot undergo phase transitions

Questão 77

Questão
Heating causes
Responda
  • cell membrane transition from the gel to fluid
  • cell membrane transition from the fluid to gel
  • cell membrane changed to become not permeable to large polar solutes
  • cell membrane changed to become permeable to small polar solutes and nonpolar compounds

Questão 78

Questão
Which of these statements on membrane fluidity is incorrect
Responda
  • is determined mainly by the fatty acid composition
  • more fluid membranes require shorter and more unsaturated fatty acids
  • At higher temperatures cells need more saturated fatty acids to maintain fluidity
  • Gel phase means that the individual molecules do not move around

Questão 79

Questão
which of these increase in membrane compisition percentage when temperatures increase
Responda
  • Myristic acid
  • palmitoleic acid
  • oleic acid
  • hydroxymyristic acid

Questão 80

Questão
Cell membranes of .... contain hopanols instead of sterols
Responda
  • animals
  • bacteria
  • plants
  • fungi

Questão 81

Questão
Membrane Dynamics: Transverse Diffusion. Spontaneous flips of individual lipids from one leaflet to another are rare because...
Responda
  • the hydrophobic head group must transverse the hydrophilic tail region of the membrane
  • membrans are rigid and individual lipids cannot move at all
  • the charged head group must transverse the hydrophobic tail region of the membrane

Questão 82

Questão
Which is false about flippases
Responda
  • catalyze transverse diffusion
  • catalyze lateral diffusion
  • use ATP
  • move lipids against the concentratiion gradient

Questão 83

Questão
Tick ALL that are true!!
Responda
  • Membrane Lipid Rafts contain clusters of glycosphingolipids with longer-than-usual tails
  • Membrane Lipid Rafts are more ordered than the rest of the membrane
  • Membrane fusion can only occur through protein mediation
  • Passive diffuision of polar molecules across cell membranes has a high activation barrier

Questão 84

Questão
Which of these is a membrane receptor that detects light
Responda
  • opsin
  • insulin receptor
  • acetylcholine receptor
  • maltoporin

Questão 85

Questão
Which of these is a membrane receptor that detects neurotransmitters
Responda
  • opsin
  • acetylcholine receptor
  • maltoporin
  • insulin receptor

Questão 86

Questão
Cystic fibrosis (Mucoviscidose) is caused by
Responda
  • a mutation to a Cl- ion channel in epithelial cells
  • a mutation to a K+ ion channel in epithelial cells
  • a mutation to a Na+ ion channel in epithelial cells
  • a mutation to a Ca2+ ion channel in epithelial cells

Questão 87

Questão
Tick ALL that are correct
Responda
  • Energy of ATP hydrolysis can be used to drive protons through the membrane
  • Energy of the proton gradient can be used to synthesize ATP
  • Primary active transport is a form of active transport across a biological membrane in which a transporter protein couples the movement of an ion (typically Na+ or H+) down its electrochemical gradient to the uphill movement of another molecule or ion against a concentration/electrochemical gradient.
  • glucose is cotransported with Na+ in intestinal epithelial cells

Questão 88

Questão
Which of these plasma proteins is the most abundant
Responda
  • transferrin
  • ceruloplasmin
  • immunoglobulins
  • albumin

Questão 89

Questão
What is labelled as B?
Responda
  • blood
  • plasma
  • White blood cells
  • ficoli

Questão 90

Questão
What is labelled as D
Responda
  • Plasma
  • White blood cells
  • Ficoli
  • white blood cells

Questão 91

Questão
Which of these are not a hematopoietic cells
Responda
  • eosinophils
  • basophils
  • neutrophils
  • thrombocytes

Questão 92

Questão
Which of these is derived from lymphoid stem cells
Responda
  • erythrocytes
  • T cells
  • basophil
  • neutrophil

Questão 93

Questão
Which one of these leukocytes secretes histamine and mediates inflammation
Responda
  • neutrophils
  • basophils
  • eosinophils
  • macrophages

Questão 94

Questão
Which of these leukocytes produces Ab (antibodies)
Responda
  • Neutrophils
  • T cells
  • B cells
  • Macrophages

Questão 95

Questão
Where is myoglobin found
Responda
  • in the bone marrow
  • freely circulating in the blood
  • in skeletal and striated muscles
  • restricted to erythrocytes

Questão 96

Questão
which of these is false
Responda
  • myogloblin stores oxygen in the cytoplasm and delivers it to mitochondrion
  • hemoglobin is restricted to erythrocytes
  • Heme (B) is the oxygen binding molecule found only in hemoglobin
  • the distal histidine of the myglobin protein hydrogen bonds with oxygen bound to the protein

Questão 97

Questão
Consider a process in which a ligand (L) bind reversibly to a site in a protein (P). After some time, the process will reach equilibrium where the Ka (association rate constant) and Kd (dissociation rate constant) rates are equal. which of these equations represents the equilibrium.
Responda
  • kd [P].[L] = ka [PL]
  • ka [P].[L] = kd [PL]
  • [P].[L] = [PL]
  • ka [P].[L] > kd [PL]

Questão 98

Questão
Which of these statements is false
Responda
  • when the first binding event increases affinity at the remaining sites it is called positive cooperativity
  • when the first binding event decreases affinity at the remaining sites it is called negative cooperativity
  • oxygen binds to heme better than carbon monoxide
  • nH( hill coefficient) > 1 equals positive cooperativity

Questão 99

Questão
Cooperativity can be described as
Responda
  • positive homotropic regulation
  • negative homotropic regulation
  • positive heterotropic regulation
  • negative heterotropic regulation

Questão 100

Questão
Which of these statement on hemoglobin is false
Responda
  • oxygen binding triggers a tense to relaxed state conformational change
  • tense state has a higher affinity for oxgen than the relaxed state
  • conformational change from the T state to the R state invloves breaking ion pairs between the alpha1-beta2 interface of hemoglobin
  • 2,3 -Bisphosphoglycerate is a negative heterotropic regulator of hemoglobin function

Questão 101

Questão
which of these is a non-phosphorylated nitrogenous base
Responda
  • nucleoside
  • nucleotide
  • nucleobase
  • nucleomide

Questão 102

Questão
Which side are the purines
Responda
  • A
  • B

Questão 103

Questão
Which color is encircling where a glycosidic bond between the nitrogenous base and the sugar would be present
Responda
  • red
  • green
  • blue
  • none of the above

Questão 104

Questão
Which letter represents deoxyadenylate
Responda
  • A
  • B
  • C
  • D

Questão 105

Questão
Which letter represents deoxythymidylate
Responda
  • A
  • B
  • C
  • D

Questão 106

Questão
Which letter represents deoxyguanylate
Responda
  • A
  • B
  • C
  • D

Questão 107

Questão
Which letter is representing cytidylate (CMP)
Responda
  • A
  • B

Questão 108

Questão
Which of these statements about the purine and pyrimidine bases is true
Responda
  • Cytosine is found in both DNA and RNA
  • Neutral molecules at pH 7
  • Guanine pKa at N7 is 2.4
  • all the above

Questão 109

Questão
In nucleotides the pentose ring is attached to the nucleobase via a
Responda
  • β -N-Glycosidic Bond
  • α -N-Glycosidic Bond
  • Hydrogen bond
  • none of the above

Questão 110

Questão
In DNA structure there is free rotation about
Responda
  • C-1’-N-glycosyl bond
  • C-2’-N-glycosyl bond
  • C-3’-N-glycosyl bond
  • C-4’-N-glycosyl bond

Questão 111

Questão
How many base pairs do you find in the A form of DNA
Responda
  • 10.5
  • 11
  • 12
  • 13

Questão 112

Questão
The aromaticity of the nucleotide bases and their dipole moments is important for which interactions in DNA
Responda
  • Van der Waal forces in base stacking
  • link between base and sugar in a nucleotide
  • the link between two different nucleotides
  • interstrand bonding and complementarity

Questão 113

Questão
Figure A represents which type of DNA secondary structure
Responda
  • hairpin
  • mirror image
  • palindrome
  • cruciform

Questão 114

Questão
Figure C represents which type of DNA secondary structure
Responda
  • Cruciform
  • Palindrome
  • Hairpin
  • Mirror image

Questão 115

Questão
DNA sequences with a very high proportion of G residues forms which unusual DNA structure found on chromosome telomeres
Responda
  • tetraplex DNA
  • triplex DNA
  • inverted repeats
  • cruciforms

Questão 116

Questão
Which of these are a quaternary DNA structure
Responda
  • Chromatin
  • hairpin
  • supercoil
  • Triplex

Questão 117

Questão
In mammals ____ Functions as an autocoid, or "local hormone"
Responda
  • Adenosine
  • Guanine
  • Cytosine
  • Thymine

Questão 118

Questão
Which one of these is an RNase enzyme that prevents inbreeding of plants
Responda
  • S-RNase
  • RNase-P
  • Dicer
  • None of the above

Questão 119

Questão
_____ is an enzyme that cleaves double-stranded RNA into oligonucleotides
Responda
  • S-RNase
  • Dicer
  • RNase P

Questão 120

Questão
Why would animal cells need an enzyme that cleaves double-stranded RNA into oligonucleotides
Responda
  • processessing tRNA precursors
  • protection from viral genomes
  • using RNA as an energy source
  • using RNA in Coenzymes

Questão 121

Questão
RNA would be unstable in which of the conditions listed below
Responda
  • pH 1
  • pH 3
  • pH 6
  • pH 10

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