601950
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
aproximadamente 10 anos atrás
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Questão 1
Questão
Pre-Proinsulin contains an R.E.R signal that moves it to the golgi
Responda
- True
- False
Questão 2
Questão
What is the role of the C-peptide part of the insulin chain
Responda
-
Formation of disulphide bonds between the alpha and beta chains
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Formation of Fe-S bonds between the alpha and beta chains
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Formation of peptide bonds between the alpha and beta chains
Questão 3
Questão
Pro-insulin is made of the alpha & beta chains and the c peptide
Responda
- True
- False
Questão 4
Questão
Which of the following cleave the c-peptide from the proinsulin?
Responda
-
Endopeptidase
-
Enteropeptidase
-
Carboxypeptidase
Questão 5
Questão
What form does newly made insulin take?
Responda
-
Granules
-
Crystals
-
Rods
Questão 6
Questão
The cleaved C-peptide is released along with the insulin
Responda
- True
- False
Questão 7
Questão
Why do Mannoheptulases inhibit insulin release?
Responda
-
The insulin secretion system relies on the phosphorylation of glucose, which MHLs inhibit
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MHLs block excretory channels
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MHLs prevent the movement of insulin to the RER
Questão 8
Questão
Optimum insulin secretion occurs at 8mM
Responda
- True
- False
Questão 9
Questão
Why is optimal secretion of insulin at 8mM
Responda
-
GLUT 2 & glucokinase have Kms of 8
-
Not gonna put anything else
-
Because reasons
Questão 10
Questão
Insulin secretion relies on ATP dependent K+ channels
Responda
- True
- False
Questão 11
Questão
K+ buildup causes Ca2+ influx and insulin secretion
Responda
- True
- False
Questão 12
Questão
Which drugs block K+ channels and mimic high glucose?
Responda
-
Sulpynoylurea
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Sulphinomides
-
Sulphinomics
Questão 13
Questão
Diazoxide causes insulin secretion by keeping channels open
Responda
- True
- False
Questão 14
Questão
High doses of adrenaline stimulates insulin secretion through _ receptors
Responda
-
Alpha 1
-
Alpha 2
-
Beta 1
-
Beta 2
Questão 15
Questão
Low concs of adrenaline inhibit insulin secretion through Beta receptors
Responda
- True
- False
Questão 16
Questão
Insulin is catabolic
Responda
- True
- False
Questão 17
Questão
Insulin stimulates _ activity in order to reduce cAMP levels
Responda
-
Phosphodiesterases
-
Adenylate cyclase
Questão 18
Questão
Which of the following metabolites are reduced?
Responda
-
Fatty Acyl CoA
-
Acetyl CoA
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Malonyl CoA
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Palmitite
Questão 19
Questão
Inc. Phosphorylation of tyrosine kinase by insulin causes what?
Responda
-
Inc tyrosine kinase activity
-
Inc phosphatase activity
-
Inc Adenylate cyclase activity
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