Islets of Langerhans & Glucagon

gina_evans0312
Quiz by , created over 5 years ago

Year 2 (Insulin & Glucagon) Quiz on Islets of Langerhans & Glucagon, created by gina_evans0312 on 03/04/2014.

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gina_evans0312
Created by gina_evans0312 over 5 years ago
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Question 1

Question
Each islet contains 3000-5000 cells
Answer
  • True
  • False

Question 2

Question
How are glucose levels monitored?
Answer
  • High blood flow around cells
  • Insulin receptors on Beta cell surface
  • Flow of glucose in interstitial fluid

Question 3

Question
What is the role of the delta cells?
Answer
  • Somatostatin production
  • Glycase production
  • Insulin production

Question 4

Question
The Islets of Langerhans are only stimulated by the SNS
Answer
  • True
  • False

Question 5

Question
What is the role of glucagon?
Answer
  • To signal 'hunger'
  • To signal 'satiation'
  • To signal high blood flow

Question 6

Question
First Pre-proglucagon is converted into Proglucagon
Answer
  • True
  • False

Question 7

Question
In the small intestine, what is made from Proglucagon?
Answer
  • Glp1 & 2
  • Major Preglucagon Fragment
  • Glucogen
  • Glycocentin

Question 8

Question
In the Alpha cells, what is made from Proglucagon?
Answer
  • GRPP
  • Glucagon
  • Major Proglucagon Fragment
  • Glycocentin

Question 9

Question
What controls glucagon secretion?
Answer
  • Nutrients
  • Gut peptides
  • Hormones
  • The nervous system

Question 10

Question
Glucose is a potent inhibitor of glucagon secretion
Answer
  • True
  • False

Question 11

Question
Amino acids and free fatty acids in the blood _ secretion
Answer
  • Stimulate
  • Inhibit

Question 12

Question
Why does glucagon have no effect on skeletal muscle?
Answer
  • So the muscles don't get depleted of glucose
  • So the muscles cannot take glucose from the blood

Question 13

Question
Glucagon stimulates insulin release
Answer
  • True
  • False

Question 14

Question
Which of the following is not a role of glucagon?
Answer
  • Mobilisation of liver glucose
  • Breakdown of TAGs to F.As
  • Inc protein synthesis
  • Inc cardiac contractility

Question 15

Question
Why does glucagon leads to the P of pyruvate kinase?
Answer
  • Reduce glycolysis & inc gluconeogenesis
  • Increase glycolysis & red gluconeogenesis

Question 16

Question
Stimulating pyruvate carboxylase stimulates glycolysis
Answer
  • True
  • False

Question 17

Question
Which of the following is deactivated in order to prevent lipogenesis
Answer
  • TAG lipase
  • Acetyl CoA carboxylase
  • Pyruvate Kinase
  • Phosphofructokinase

Question 18

Question
Phosphofructokinase 2 activates gluconeogenesis & inhibits glycolysis
Answer
  • True
  • False