Insulin Receptors

gina_evans0312
Quiz by , created over 5 years ago

Year 2 (Insulin & Glucagon) Quiz on Insulin Receptors, created by gina_evans0312 on 03/06/2014.

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gina_evans0312
Created by gina_evans0312 over 5 years ago
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Question 1

Question
Where is the carboxylase termunus regulatory region found?
Answer
  • Inside the cell
  • Outside the cell
  • In the membrane

Question 2

Question
How are the alpha and beta chains connected?
Answer
  • Electrostatic interactions
  • Disulphide bonds

Question 3

Question
What is the active site of insulin receptor?
Answer
  • Tyrosine kinase
  • Skeletons
  • Toast

Question 4

Question
The active site of Insulin receptors work exactly the same as other tyrosine kinases
Answer
  • True
  • False

Question 5

Question
What does IRS stand for?
Answer
  • Inland Revenue Service
  • Insulin Receptor Substrate

Question 6

Question
There are six different versions of the IRS
Answer
  • True
  • False

Question 7

Question
How does the IRS bind to the Insulin receptor?
Answer
  • PTB- Phosphotyrosine Binding Site
  • PSB- Phosphoserine Binding Sire

Question 8

Question
The Insulin Receptor response pathway is the same as the MAPK pathway until MAPK activates
Answer
  • Insulin Sensitive Protein Kinase (ISPK)
  • Insulin Responsive Protein Kinase (IRPK)
  • Insulin Dependent Protein Kinase (IDPK)

Question 9

Question
ISPK activates Protein Phosphatase 1, which reverses te effect of adrenaline/glucagon through phoshphorylation
Answer
  • True
  • False

Question 10

Question
IRS can also work through the PI3K pathway, leading to the conversion of PI2 to what?
Answer
  • PI
  • PI3
  • PI-2,5-BP

Question 11

Question
The action of the PI3K pathway causes the activation of PKB
Answer
  • True
  • False

Question 12

Question
The P of PKB causes the P and deactivation of what?
Answer
  • Glycogen Synthase Kinase-3
  • Glycogen Phosphorylase

Question 13

Question
Why does PKB increase phosphodiesterase activity?
Answer
  • Reverses phosphorylation done by glucaon
  • Lowers cAMP