Quiz
Antibacterial Drugs (Antibiotics)- Pharmacology- 4th Year- PMU
Perguntas do quiz (42)
1Bactericidal antibacterial drugs:
- Ainhibit the growth of microorganisms
- Binhibit the multiplication of microorganisms
- Ckill the microorganisms
- Dblock the enzyme penicillinase
2Antimicrobials with bactericidal activity are:
- Abeta-lactam antibiotics
- Bamphenicols and lincosamides
- Caminoglycosides
- Dquinolones
3Bacteriostatic action means:
- Ainhibition of the growth of microorganisms
- Binhibition of the multiplication of microorganisms
- Cdestruction of microorganisms
- Dinhibition of the enzyme penicillinase
4Bacteriostatic antimicrobials are:
- Aamphenicols
- Baminoglycosides
- Ctetracyclines and macroiides
- Dlincosamides
5Narrow spectrum antimicrobial drugs are active against:
- AGram (+) cocci
- BGram (+) bacteria
- CFungi and viruses
- DParasites
6Antimicrobials with a narrow spectrum of activity are:
- Aclassic penicillins
- Blincosamides
- Caminoglycosides
- Dclassic macrolides
7Antimicrobials with broad spectrum of activity are:
- Acephalosporins
- Baminopenicilins
- Clincosamides
- Drifamycins
8Antimicrobials that inhibit bacterial cell wall synthesis are:
- Apenicillins
- Bcephalosporins
- Cmonobactams
- Dtetracyclines
9Antimicrobial that inhibit protein synthesis in microorganisms are:
- Atetracyclines
- Bmacrolldes
- Cquinolones
- Dcarbapenems
10Antibiotics that inhibit DNA synthesis in microorganisms are
- Acephalosporins
- Bquinolones
- Cmacrolides
- Drifampicin
11Antibiotics that must be avoided during pregnancy are:
- Atetracyclines
- Bpenicillins
- Ccephalosporins
- Drifampicin
12Antimicrobial agents with urine excretion are:
- Apenicillins
- Bcephalosporins
- Caminoglycosides
- Dquinolones
13Antimicrobial agents with bile excretion are:
- Atetracyclines
- Baminoglycosides
- Cmacrolides
- Dsulfonamides
14Optimal combinations of antimicrobial agents are:
- Abactericidal antibiotics with bactericidal antibiotics
- Btetracyclines with macrolides
- Cbactericidal antibiotics with bacteriostatic antibiotics
- Dpenicillins with B-lactamase inhibitors
15Tetracyclines
- Aare bactericidal
- Bae bacterostatic
- Caccumulate in tissues- in bones and teeth
- Dare effective against rickettsiae, mycoplasma, chlamydia
16Which foods and drugs interact with tetracyclines' gastrointestinal absorption?
- AVitamin B1
- BYogurt or Cheese
- CFe2+ or Mg2+ containing drugs
- DAminoglycosides
17Adverse drug reactions of tetracyclines are:
- Anephro-and ototoxicity
- Bhepatotoxicity
- Cyellow-brown discoloration of teeth and frequent tooth decay in children
- Dinhibition of bone growth in children
18Tetracyclines are contraindicated in:
- Apregnancy
- Bchildren less than 8 years
- Cliver failure
- Dheart failure
19Macrolide antibiotics are:
- AAzithromycin (Azatril)
- BRoxithromycin (Rulid)
- CClarithroomycin (Klacid)
- DGentamycin
20Macrolides are:
- Abactericidal
- Bbacteriostatic
- Cinhibitors of methylxanthines’ metabolism
- Deffective against mycoplasmas, Legionella, Chlamydia
21Adverse drug reactions of macrolides include:
- Agastrointestinal disturbances
- Ballergy
- Chepatotoxicity
- Dnephrotoxicity
22Macrolides are contraindicated in:
- APregnancy in the first half
- BG-6-PDH deficiency
- CLiver failure
- DBreastfeeding
23Lincosamides:
- Aare bacteriostatic antibiotics
- Bare appropriate for the treatment of staphylococcal osteomyelitis
- Ccan be hepato- and haematotoxic
- Daccumulate in the bone marrow
24Lincosamides are contraindicated in:
- Apregnancy
- Bchildren less than 2 years
- Cliver failure
- Dheart failure
25Chloramphenicol:
- Ais a bactericidal antibiotic
- Bis effective against Gram (-) microorganisms
- Cis a tetracycline derivative
- Dinhibits alcohol dehydrogenase enzyme
26The correct statements for Chloramphenicol are:
- AIt is used as a reserve antibiotic because of many ADRs
- BCauses gastrointestinal disbacteriosis
- CCan be administered orally
- DIt Is used for the treatment of tuberculosis
27Adverse drug reactions of Chloramphenicol are:
- Adamage of teeth enamel
- B"gray baby" syndrome
- Cdisulfiram- alcohol reaction
- Dbone marrow supression (myelotoxicity)
28Chloramphenicol is contraindicated in:
- APregnancy
- BChildren less than 2 years
- CAlcoholism
- DG-6-PDH deficiency
29Beta-lactam antibiotics are
- Apenicillins
- Bcephalosporins
- Cmonobactams
- Dcarbapenems
30Narrow spectrum (classic) penicillins are:
- AAmoxicillin
- BBenzylpeniciliin (Penicilin G)
- CPhenoxymethylpenicillin (Ospen)
- DOxacillin
31Broad spectrum semisynthetic penicillins are:
- AAmoxicillin (Amopen)
- BAmpicillin
- CAzlocillin
- DGentamycin
32Adverse drug reactions of penicillins are:
- Aallergic reactions
- Bhepatotoxicity
- Canaphylactic shock
- Ddisbactenosrs (for orally administered broad-spectrum penicillins)
33Penicillins and cephalosporins block the synthesis of:
- Athe bacterial cell wall
- Bthe bacterial membrane
- Cproteins
- Dnucleic acids
34Cephalosporins 1st generation are:
- AMore effective against Gram (+) microorganisms
- BCefalexin and Cefazolin
- CBacteriostatic
- DSome agents are nephrotoxic
35Cephalosporins 2nd generation are:
- ABactericidal
- BCefaclor and Cefamandol
- CMore effective against Gram (-) organisms: Klebsiella, H. lnfluenzae
- DWith high bile concentrations (most of them)
36Cephalosporins 3rd generation are:
- ACefetamet and Ceftriaxon
- BCefaclor and Cefamandol
- CMore effective against Gram (-) microorganisms
- DUsed for treatment of life-threatening infections
37Cephalosporins 4th generation are:
- ACefepim and Cefpifom
- BNarrow spectrum antibiotics
- CEffective against Gram (-) microorganisms as 3rd generation and against Gram (+) as 1st generation cephalosporins
- DUsed for treatment of life-threatening infections
38Adverse drug reactions of cephalosporins are:
- Aallergic reactions
- Bsuppressed vitamin K synthesis
- Chepatotoxicity
- Dnephrotoxicity
39Aminoglycoside antibiotics are:
- AGentamaicin
- BAmoxiclav
- CAmikacin
- DTobramycin
40The correct statements of aminoglycoside antibiotics are:
- Athey block protein synthesis and are bactericidal
- Bthey accumulate in soft tissues and bones
- Cthey are administrated orally for treatment of urinary infections
- Dthey are effective against Gram (-) microorganisms
41Adverse drug reactions of aminoglycosides are:
- Anephrotoxicity
- Bototoxicity
- Cmyelotoxlcity
- Dhepatotoxiclty
42Aminoglycosides are contraindicated in:
- Apregnancy
- Bchildren less than 2 years
- Crenal failure
- Dliver failure
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- Antibacterial Drugs (Antibiotics)
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- Criado em 18 out 2018 · atualizado em 18 out 2018
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