Quiz
Cholinergic Drugs- Pharmacology 4th Year- PMU
Perguntas do quiz (27)
1Point out the cholinergic neurons
- Apreganglionic sympathetic
- Bpostganglionic sympathetic
- Cpreganglionic parasympathetic
- Dpostganglionic parasympathetic
2Muscarinic cholinergic receptors are located in:
- Askeletal muscles
- Bbronchial smooth muscles
- Cheart
- Dsmooth muscles of GIT
3Nicotinic cholinergic receptors are located in:
- Aautonomic ganglia
- Badrenal gland medulla
- Cheart muscle
- Dskeletal muscles
4Pharmacological effects of Acetylcholine are:
- Abradycardia
- Btachycardia
- Cincreased digestive (abundant saliva), bronchial, cutaneous, (sweat) and lacrimal secretions
- Dincreased tone and peristaltic contractions of GIT
5M-receptor agonist used for treatment of glaucoma is:
- AAtropini sulfas
- BPilocarpini hydrochloridum
- CNeostigmini methylsulfas
- DGalantamini bromidum
6What are the effects of Pilocarpine after eye application?
- Amydriasis
- Bmiosis
- Cincreases the intraocular pressure
- Ddecreases the intraocular pressure
7Clinical indications for prescribing N-receptor agonists are:
- Asmoking cessation
- Batherosclerosis
- Cpremedication in anesthesia
- Dmuscle relaxation
8Acetylcholine esterase inhibitors (anticholinesterases) are:
- Alpratropii bromidum
- BGalantamine bromidum
- CNeostigmine methylsulfas
- DPyridostigmine bromidum
9Indications for the clinical use of anticholinesterases are:
- Aparalytic ileus
- Batropine intoxication
- Cspastic bronchitis
- Das antidote of tubocurarine
10Anticholinesterases are contraindicated in:
- Abronchial asthma
- Bparalytic ileus
- Cepilepsy
- Dbradycardia
11Point out the major features of the irreversible acetylcholine-esterase inhibitors:
- AThey are organophosphate agents
- BCause long-lasting elevation of acetylcholine levels
- CTheir effect is antagonized by cholinolytic agents
- DObidoxime is their specific antagonist
12Symptoms of organophosphate intoxication can be treated with:
- AAcetylcholine
- BAtropine sulphas
- CReactivators of acetylcholine esterase enzyme
- DInhibitors of acetylcholine esterase
13Antimuscarinic receptor antagonists are:
- AAtropini sulfas
- BButylscopolamine
- CAtracurium besilas
- DIpratropium bromidum
14Synthetic antimuscarinic drugs are:
- APilocarpini hydrochloridum
- BIpratropium bromidum
- CButylscopolamine
- DTiotropium bromidum
15Pharmacological effects of antimuscarinic drugs are:
- Atachycardia
- Bintestinal smooth muscle relaxation
- Cmydriasis
- Ddecrease the secretion of exocrine glands
16Clinical indications for prescribing antimuscarinic drugs are:
- Abronchial asthma
- Bspasm of the smooth muscles of GlT
- Cto elicit papillary dilation
- Dglaucoma
17Adverse drug reactions of Atropine are:
- Adry mouth
- Btachycardia
- Cdifficulties in seeing close objects
- Ddisorientation and hallucinations
18Symptoms of intoxication with antimuscarinic agents are treated with:
- AObidoxime
- BAnticholinesterases
- CAtropine sulphas
- DAcetylcholine
19Non-depolarizing neuromuscular blockers paralyse the skeletal muscles in the following order:
- Ahead and neck, limbs, trunk, diaphragm and intercostal muscles
- Blimbs, trunk, diaphragm and intercostal muscles, head and neck
- Cdiaphragm and intercostal muscles, head and neck, limbs
- Dtrunk, diaphragm and intercostal muscles, head and neck, limbs
20Which of the following drugs are non-depolarising muscle blockers?
- AAtracurium besilas
- BPancuronium bromidum
- CSuxamethonium chloridum
- DTubocurarine hydrochloridum
21Adverse drug reactions of non-depolarizing muscle relaxants are:
- Ahistamine release
- Bhypotension
- Chypertension
- Dallergic reaction
22Drug interactions can occur in concomitant use Of peripheral-acting muscle relaxants and:
- Aaminoglycoside antibiotics
- Bcalcium antagonists
- Chalogen anaesthetics
- Dcardiac glycosides
23Which of the following drugs will antagonise the effect of the non-depolarizing neuromuscular blockers?
- AAnticholinesterases
- BMAO inhibitors
- CAntimuscarinic agents
- DAminoglycoside antibiotics
24What are the main features of Suxamethonium chioridum:
- Ashort-lasting effect
- Bhas no antagonist
- Canticholinesterases prolong its effect
- Doral administration
25Adverse drug reactions of depolarizing muscle relaxants are-
- Atremor
- Barrhythmia
- Callergic reactions
- Dprolonged neuromuscular blockade in people with plasma cholinesterase deficiency
26Indications for treatment with central muscle relaxants are-
- Aspasms of the skeletal muscles as a result of CNS damage
- Bmultiple sclerosis
- Csurgery interventions
- Dmyasthenia gravis
27Which of drugs are central acting muscle relaxants?
- ATetrazepam
- BTolperison
- CBromocriptine
- DBaclofen
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