11159505
Description
Quiz by Michael Jardine, updated more than 1 year ago
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Created by Michael Jardine
over 6 years ago
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Question 1
Question
The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?
Answer
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Sagittal Central Nucleus
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SupraCentral Nucleus
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Sagittal Cortical Nucleus
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SupraCortical Nucleus
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SupraChiasmal Nucleus
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Sagittal Chiasmal Nucleus
Question 2
Question
The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?
Answer
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PER
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CRY
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RORa
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CCGs
Question 3
Question
Deepest sleep [normally] occurs at what time?
Answer
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12am
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1am
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2am
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3am
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4am
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4:30am
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6am
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6:30am
Question 4
Question
Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:
Answer
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Blood transcriptome
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Plasma transcriptome
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Renal transcriptome
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Mitochondrial transcriptome
Question 5
Question
Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:
Answer
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Delayed Sleep Phase Disorder (DSPD)
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Advanced Sleep Phase Disorder (ASPD)
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Non-24-Hour Sleep-Wake Syndrome
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Irregular Sleep-Wake Rhythm (ISWR)
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Shift Work Sleep Syndrome
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Time Zone Change Syndrome
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Free-Running Disorder (FRD)
Question 6
Question
Free-Running Disorder (FRD) is:
Answer
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A progressive pattern of 1- to 2- hour delays in sleep onset and wake times
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Temporally disorganised and variable episodes of sleeping and waking behaviour with short sleep periods of a few hours that are distributed randomly through the day and night
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Somnambulism
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Sleepwalking
Question 7
Question
The endogenous cycle is how many hours?
Answer
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23
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24
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25
Question 8
Question
Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:
Answer
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Extreme eveningness preference
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Extreme morningness preference
Question 9
Question
Treatments of human circadian rhythm disorders include:
Answer
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Timed melatonin administration
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Phase resetting – bright light administration
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Melatonin agonists
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Toughening the fuck up
Question 10
Question
Disruption of circadian rhythms can lead to:
Answer
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Metabolic Imbalance
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Disruption in melatonin levels
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Disruption in blood glucose levels
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Insulin resistance
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Crankiness
Question 11
Question
True or false: Circadian rhythm disruptions have been linked to cancer.
Answer
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True
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False
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...true AND false.
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