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Biochem Sem 2 - alcohol

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biochem Quiz on Biochem Sem 2 - alcohol, created by Alannah McDonnell on 26/02/2018.
Alannah McDonnell
Quiz by Alannah McDonnell, updated more than 1 year ago
Alannah McDonnell
Created by Alannah McDonnell about 6 years ago
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Resource summary

Question 1

Question
How much alcohol is absorbed in the stomach
Answer
  • 20%
  • 90%
  • 5%
  • 0.5%

Question 2

Question
How much alcohol is metabolized by the liver?
Answer
  • 20%
  • 90%
  • 5%
  • 0.5%

Question 3

Question
How much alcohol is excreted by urine?
Answer
  • 20%
  • 90%
  • 5%
  • 0.5%

Question 4

Question
How is alcohol absorbed along the entire GI tract?
Answer
  • simple diffusion
  • active transport
  • osmosis
  • ion gated channels

Question 5

Question
What do alcoholic beverages primarily consist of?
Answer
  • water
  • starch
  • ethanol
  • sugar
  • protein
  • lipids

Question 6

Question
Which of these factors will allow you to drink more alcohol for a lower blood alcohol level content?
Answer
  • weight
  • Male
  • Female
  • empty stomach
  • full stomach
  • carbonated mixers

Question 7

Question
Which of the following statements is true?
Answer
  • Class 1 ADHs have a low Km for ethanol
  • Class 1 ADHs have the lowest specificity for EtOH
  • CYP2E1 has a lower Km for ethanol than class 1 ADHs
  • Chronic alcohol consumption suppresses P450 enzyme systems
  • Acute effects of ethanol arise from the increased NAD+/NADH ratio

Question 8

Question
What are the two primary pathways of alcohol metabolism? C[blank_start]ytosol[blank_end] A[blank_start]lcohol[blank_end] D[blank_start]ehydrogenade[blank_end] (ADH) M[blank_start]icrosomal[blank_end] ethanol-o[blank_start]xidizing[blank_end] s[blank_start]ystem[blank_end] (MEOS)
Answer
  • Cytosol
  • cellular
  • Alcohol
  • Adenine
  • Dehydrogenase
  • Deoxygenated
  • Dehydrator
  • Microsomal
  • Marcoscopic
  • oxidizing
  • oxidation reaction
  • system
  • series

Question 9

Question
Which pathway is used for beaking down small amounts of alcohol?
Answer
  • Cytosol Alcohol Dehydrogenase
  • Microsomal Ethanol-oxidizing system

Question 10

Question
Which pathway is important for breaking down large amounts of alcohol?
Answer
  • Microsonmal Ethanol-Oxidizing System
  • Alcohol dehyrogenase

Question 11

Question
What can alcohol be metabolized to in the colon?
Answer
  • ethanol
  • acetaldehyde
  • starch
  • dangerous bacteria

Question 12

Question
What is the alcohol metabolized by in the colon?
Answer
  • Colon Bacterial ADH
  • Bacteria
  • amalase
  • MEOS

Question 13

Question
What is acetaldehyde?
Answer
  • a toxic compound
  • a non-toxic compount

Question 14

Question
What is one major effect of low doses of alcohol?
Answer
  • slowing the citric cycle
  • use of MEOS
  • chance of alcoholism
  • stomach issues

Question 15

Question
*** what is alcohol dehydrogenase?
Answer
  • a family of isoenzymes
  • cool

Question 16

Question
Which ADH has the highest specificity for ethanol?
Answer
  • class 1 ADHs
  • class 2 ADHs
  • class 4 ADHs
  • they're all equal

Question 17

Question
How many genes are there for class 1 ADH?
Answer
  • 1
  • 2
  • 3
  • 4
  • 5

Question 18

Question
What do the genes for class 1 ADH exist as?
Answer
  • allelic variants
  • polymorphisms

Question 19

Question
which ADH class is high in the liver?
Answer
  • 1
  • 2
  • 3
  • 4

Question 20

Question
what ADH class can be found in GIT?
Answer
  • 1
  • 2
  • 3
  • 4

Question 21

Question
which of these two are functional polymorphisms
Answer
  • ADH 1A and ADH 1C
  • ADH 2A and ADH 1C
  • ADH 1X and ADH X

Question 22

Question
***what can partially account for observed differences in ethanol elimination rates among individuals or population?
Answer
  • functional polymorphisms
  • eating habits

Question 23

Question
Possession of which allele is associated with decreased susceptibility to alcoholism?
Answer
  • ADH 1B*2
  • ADH 1B*3
  • ADH 1A*2
  • ADH 1A*3

Question 24

Question
What does ADH1B*2 code for?
Answer
  • a relatively fast ADH
  • a relative slow ADH

Question 25

Question
ALDH = A[blank_start]cetaldehyde[blank_end] D[blank_start]ehydrogenase[blank_end]
Answer
  • cetaldehyde
  • ehydrogenase

Question 26

Question
What type of ALDH is cytosolic?
Answer
  • ALDH 1
  • ALDH 2
  • ALDH 3

Question 27

Question
What does accumulation of acetylaldehyde cause?
Answer
  • nausea
  • vomiting
  • chest pains
  • hunger
  • thirst

Question 28

Question
What can an ALDH inhibitor be used for?
Answer
  • Drug treatment for alcoholism
  • cure for thirst
  • it can't be used for anything, it's toxic
  • liver repair

Question 29

Question
what does metabolism of acetate require?
Answer
  • activation to acetyl CoA
  • deactivation from acetyl CoA
  • reduction of Fatty Acids
  • removal of a phosphate group
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