Parkinsons epidemiology: prevalence is [blank_start]0.5-1[blank_end]% in the UK in >[blank_start]60[blank_end]'s. it is the second most common neurodegenerative disorder after alzeheimers. the mean age of onset is [blank_start]45-60[blank_end] but it can occur in people as young as [blank_start]30[blank_end]. there are [blank_start]120,000[blank_end] people living with parkinsons in the UK.
which of the following is not a cause of parkinsons
heavy metal exposure
repeated head trauma
parkinsons results from the loss of [blank_start]dopaminergic neurons[blank_end] in the [blank_start]basal ganglia[blank_end] most notably the [blank_start]substantia nigra[blank_end] which usually synthesises [blank_start]dopamine[blank_end]. surviving neutrons contain aggregations of protein ([blank_start]alpha-synuclein[blank_end]) called [blank_start]lewy bodies[blank_end]. symptoms are only seen once levels of dopamine are [blank_start]20-40%[blank_end] of normal. the disease is slowly progressive without remission.
which of the following is not part of the classic triad for parkinsons?
which of the following is not a symptom of parkinsons?
loss of sense of smell
slurred slow speech
REM sleep disturbance
sluggish bowel and bladder
vertical gaze palsy
what is the name of the scan that can be used to diagnose dementia? [blank_start]DAT[blank_end]
mark on the DAT scan which is normal and which is abnormal
what is the name of the criteria that can be helpful is diagnosing parkinsons? [blank_start]brain bank[blank_end]
In younger patients you would start by treating them with L-dopa instead of dopamine agonists
match each of the following types of parkinsons medication to the examples:
l-dopa - [blank_start]madapar[blank_end]
selective dopamine agonist - [blank_start]pramipexole[blank_end], [blank_start]bromocriptine[blank_end]
increases dopamine release - [blank_start]amantadine[blank_end]
MAO-B inhibitors - [blank_start]selegilene[blank_end]
COMTI - [blank_start]tolcapine[blank_end]
never prescribe haloperidol for a parkinsons patients
which of the following is not a treatment for parkinsons?