Clinical biochemistry

Description

Liver disease test
Thomas Hardwick
Quiz by Thomas Hardwick, updated more than 1 year ago
Thomas Hardwick
Created by Thomas Hardwick about 6 years ago
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Resource summary

Question 1

Question
Which of the following is an inherited disorder of bilirubin metabolism?
Answer
  • All answers are correct
  • Crigler-Najjar syndrome
  • Gilbert’s disease
  • Dubin-Johnson syndrome

Question 2

Question
Which of the following enzymes would be raised in serum from a patient with hepatocellular disease?
Answer
  • Creatine kinase
  • Lactate dehydrogenase
  • Alanine amino transerferase
  • Ferroxidase

Question 3

Question
Which of the following is the major liver metabolite of bilirubin
Answer
  • stercobilin
  • bilirubin monoglucuronide
  • unconjugated bilirubin bilirubin diglucuronide
  • bilirubin diglucuronide

Question 4

Question
Which of the following does not cause chronic liver disease?
Answer
  • Hepatitis A
  • Hepatitis C
  • Chronic high alcohol ingestion
  • Hepatitis B
  • none of them

Question 5

Question
Which of the following best defines jaundice?
Answer
  • Yellow discolouration of the skin or sclera of the eye, due to increased bilirubin in plasma >40umol/l Low serum bilirubin concentration
  • Increased bilirubin in plasma >40umol/l
  • Brain damage due to high bilirubin concentrations
  • Low serum bilirubin concentration

Question 6

Question
Which of the following can arise as a result of acute hepatic failure?
Answer
  • Acid-base disturbance
  • Hypoglycaemia
  • Electrolyte imbalance
  • All answers are correct

Question 7

Question
Which of the following can be a cause of acute liver disease?
Answer
  • Heart failure leading to inadequate liver perfusion
  • Paracetamol poisoning
  • All answers are correct
  • Hepatitis B

Question 8

Question
Which is found in haemolytic jaundice?
Answer
  • Increased serum haptoglobins
  • Low serum unconjugated bilirubin
  • Pale stools due to decreased bilirubin metabolites
  • High serum unconjugated bilirubin

Question 9

Question
Which of the following can cause liver cirrhosis?
Answer
  • All answers are correct
  • Chronic high alcohol ingestion
  • Chronic hepatitis B infection
  • Anti-mitochondrial antibodies

Question 10

Question
Which is found in obstructive jaundice?
Answer
  • High serum unconjugated bilirubin
  • High serum conjugated bilirubin
  • Dark stools due to increased bilirubin metabolites
  • Increased serum haptoglobin
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