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Analgesia

Matthew Coulson 11 questions

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  1. 1The WHO Analgesic ladder (least potent at top):
    [blank_start]Paracetamol[blank_end]
    [blank_start]NSAID[blank_end]
    [blank_start]Weak Opioid[blank_end]
    [blank_start]Strong Opioid[blank_end]
    1. AParacetamol
    2. BNSAID
    3. CWeak Opioid
    4. DStrong Opioid
  2. 2Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
    [blank_start]Paracetamol[blank_end]
    [blank_start]Ibuprofen[blank_end]
    [blank_start]Codeine[blank_end]
    [blank_start]Morphine[blank_end]
    1. AParacetamol
    2. BIbuprofen
    3. CCodeine
    4. DMorphine
  3. 3Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
    [blank_start]Paracetamol[blank_end]
    [blank_start]Indomethacin[blank_end]
    [blank_start]Tramadol[blank_end]
    [blank_start]Oxycodone[blank_end]
    1. AParacetamol
    2. BIndomethacin
    3. CTramadol
    4. DOxycodone
  4. 4Opioids provide analgesia via inhibition of voltage gated [blank_start]Calcium[blank_end] channels and promotion of [blank_start]Potassium[blank_end] channel opening (to suppress excitation of projection neurons)
    1. ACalcium
    2. BPotassium
    3. CSodium
    4. DPotassium
    5. EChlorine
    6. FCalcium
    7. GSodium
  5. 5Opioid receptors are distributed throughout the nervous system and are traditionally arranged into three classes. Which class is responsible for most of the analgesic action of opioids?
    1. Aμ (mu)
    2. Bδ (delta)
    3. Cκ (kappa)
  6. 6Tramadol is a weak [blank_start]μ[blank_end] receptor agonist
    1. Aμ
    2. Bκ
    3. Cδ
  7. 7Epileptic patients should not be given which of the following analgesics?
    1. ATramadol
    2. BMethadone
    3. CMorphine
    4. DCodeine
  8. 8Which analgesic is given to aid withdrawal symptoms from strong opioids such as heroin?
    [blank_start]Methadone[blank_end]
    1. AMethadone
  9. 9Patients who experience an overdose of a strong opioid can be reversed using a short acting μ-receptor antagonist called [blank_start]Naloxone[blank_end]
    1. ANaloxone
  10. 10The therapeutic benefit of NSAIDs largely comes via inhibition of which COX receptor?
    1. ACOX1 Receptor
    2. BCOX2 Receptor

Information

Description
Analgesia lecture given by John Peters in Week 5. Lots of information but have only taken what are in my view the main learning points.
Language
English
Views
258
Tags
analgesiapharmacologyneuroneurologydrugsmedicationpainkillermedicineneurology - week 5honours degree
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