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Micro LABMED
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Questions in this quiz (97)
1Yeasts are microscopic multicellular organisms that reproduce by budding
- ATrue
- BFalse
2Dimorphic fungi are moulds in the environment, but behave as yeast in the human host
- ATrue
- BFalse
3Athlete's foot is caused by the pathogen candida glabrata
- ATrue
- BFalse
4Onchomycosis can be treated using either itraconazole or the allyamine terbinafine
- ATrue
- BFalse
5Candida albicans is the most prolific subtype of the species
- ATrue
- BFalse
6Candida infections are solely superficial
- ATrue
- BFalse
7Symptoms of vulvovaginal candidiasis include:
extreme vaginal itching, burning sensation during urination and a cottage-cheese-like vaginal discharge- ATrue
- BFalse
8Vulvovaginal candidiasis can be managed with either a topical antifungal such as nystatin, or a systemic azole such as butoconazole
- ATrue
- BFalse
9Oropharyngeal candidiasis is associated with the development of a squamous cell carcinoma in the affected region
- ATrue
- BFalse
10Candida is the most common bloodstream pathogen
- ATrue
- BFalse
11Vascular catheters are an important risk factor in the development in candidaemia
- ATrue
- BFalse
12Candida parapsilosis is a new species of Candida that has been identified and has caused a significant number of fatalities while proving to be MDR
- ATrue
- BFalse
13Aspergillosis innoculation occurs via inhaling the spores into the lungs
- ATrue
- BFalse
14A presentation of pulmonary aspergillosis is associated with the halo sign on CXR
- ATrue
- BFalse
15COPD and sarcoidosis are lung conditions that are associated risk factors for the development of aspergillosis
- ATrue
- BFalse
16The recommended treatment for aspergillosis is the polyene Amophotericin B
- ATrue
- BFalse
17Cryptococcus can contracted from mouth-to-mouth resuscitation of an immunocompromised patient in the case of cardiac arrest if more than 52 consecutive cycles are performed without break
- ATrue
- BFalse
18A recognised complication of cryptococcosis is the development of subacute meningitis
- ATrue
- BFalse
19Cryptococcosis is infamous as an opportunistic infection contracted by patients suffering from AIDS
- ATrue
- BFalse
20A lumbar puncture is performed as part of the diagnosis of cryptococcus, and the sample of CSF obtained should display high WBC and elevated protein levels
- ATrue
- BFalse
21Solid organ transplant is a risk factor implicated in both aspergillosis and cryptococcosis infections
- ATrue
- BFalse
22Patients with haematological malignancies are at a statistically significant reduced risk of contracting a fungal infection
- ATrue
- BFalse
23PCP pneumonia is associated with the pathogen pneumocystis jirovecci
- ATrue
- BFalse
24Broncho-alveolar lavage is crucial in the diagnosis of PCP
- ATrue
- BFalse
25The recommended treatment for PCP is co-trimoxazole
- ATrue
- BFalse
26Mucormycosis is a smaller species than Aspergillosis
- ATrue
- BFalse
27In mucormycosis the hyphae that germinate grow in and around blood vessels
- ATrue
- BFalse
28Flucytosine is an example of an allyamine antifungal
- ATrue
- BFalse
29Amphotericin B can have nephrotoxic side effects
- ATrue
- BFalse
30Fluconazole is first line treatment for the flu
- ATrue
- BFalse
31Triazoles interfere with the synthesis of ergosterol via the inhibition of lanosterol 14alpha demethylase
- ATrue
- BFalse
32A new generation of antifungals, the candins, target cell glucan synthesis
- ATrue
- BFalse
33Terbinafine can cause a decrease in WBC along with GI and CNS disturbances
- ATrue
- BFalse
34Mutations in ERG11 increase azole efflux from the pathogen which contributes to acquired resistance to these antifungals
- ATrue
- BFalse
35One of the necessary points in Koch's postulates is that the pathogen must be found in at least 80% of the cases of the disease
- ATrue
- BFalse
36H pylori is from the order Campylobacterales
- ATrue
- BFalse
37H pylori is a curved Gram negative bacillus
- ATrue
- BFalse
38LPS is found in the outer membrane of H pylori and is responsible for its inflammatory activity
- ATrue
- BFalse
39H pylori must be grown in a selective Skirrow medium for 2-5 days at 37 degrees celsius
- ATrue
- BFalse
40H pylori is not urease positive
- ATrue
- BFalse
41H pylori has a particular fondness of gastric epithelium in the antrum of the stomach
- ATrue
- BFalse
42H pylori is highly motile with a number of polar flagellae
- ATrue
- BFalse
43cagA is protective in oesophageal carcinoma but causative in gastric carcinoma
- ATrue
- BFalse
44Urease is an enzyme that breaks down urea to form ammonia, allowing H pylori to adapt to the acidic environment
- ATrue
- BFalse
45H pylori is an invasive pathogen
- ATrue
- BFalse
46Virulence factors associated with H pylori include cagA and vacA
- ATrue
- BFalse
47Platelet activating factor causes an increase in gastric acid secretion
- ATrue
- BFalse
48Patients are delighted to be told they are cagA positive when being tested for H pylori
- ATrue
- BFalse
49vacA results in the vacuolation of tissue through interaction with the gastric epithelium
- ATrue
- BFalse
50H pylori is catalase positive, allowing it to evade the immune system through the degradation of hydrogen peroxide
- ATrue
- BFalse
51H pylori is scarcely seen in developing countries
- ATrue
- BFalse
52Individuals positive for H pylori have a 10-20% chance of developing gastric adenocarcinoma
- ATrue
- BFalse
53Patients who present with duodenal ulceration usually have a pre-existing antral non-atrophic gastritis from H pylori colonisation
- ATrue
- BFalse
54Stool antigen tests are the preferred diagnostic test in the management of suspected H pylori infection
- ATrue
- BFalse
55Triple therapy is the recommended treatment for H pylori infection
- ATrue
- BFalse
56The duration of triple therapy treatment for H pylori is 10 days
- ATrue
- BFalse
57Mycobacterium are acid-fast, aerobic and difficult to stain
- ATrue
- BFalse
58Mycobacterium are difficult to kill because they cause the production of interferon gamma which inhibits leukocyte recruitment
- ATrue
- BFalse
59The Mantoux test is based on the type III hypersensitivity reaction
- ATrue
- BFalse
60For the diagnosis of pulmonary TB, three early morning sputum samples are needed to send to the lab for analysis, along with a bronchoalveolar lavage and a pleural fluid aspiration
- ATrue
- BFalse
61GeneXpert analysis can identify resistant strains of rifampicin
- ATrue
- BFalse
62IFN gamma test is useful in the rapid investigation of primary progressive TB
- ATrue
- BFalse
63Isoniazid is an antibiotic used in the treatment of TB which inhibits the synthesis of mycolic acids which are needed for cell wall synthesis
- ATrue
- BFalse
64Rifampicin inhibits DNA dependent RNA polymerase and is an enzyme inhibitor
- ATrue
- BFalse
65Aminoglycosides and Fluoroquinolones can be used as 2nd line treatment in TB
- ATrue
- BFalse
66Recently developed drugs for the management of MDR-TB are bedaquiline and declanamide
- ATrue
- BFalse
67MDR-TB is resistant to 4 or more anti-TB agents
- ATrue
- BFalse
68Ethambutol is a useful second line agent in the treatment of TB
- ATrue
- BFalse
69A year long course of Isoniazid is used as chemoprophylactic treatment for TB
- ATrue
- BFalse
70A mode of acquisition of TB is via the tickling of one's left nostril with a dead pigeon feather
- ATrue
- BFalse
71Extrapulmonary TB can present as vertebral osteomyelitis, renal TB, meningitis, TB epididymis, lupus vulgaris and cervical lymphadenopathy
- ATrue
- BFalse
72M. chimera is part of the MAC complex that affects immunocompromised patients
- ATrue
- BFalse
73TB therapy is at least 6 months in duration
- ATrue
- BFalse
74Longer therapy for TB is required if the patient presents with meningitis, osteomyelitis or the patient is HIV+
- ATrue
- BFalse
75Infective endocarditis in IVDU usually affects the tricuspid valve
- ATrue
- BFalse
76A patient with a prosthetic valve and candidaemia has a 40% chance of developing infective endocarditis
- ATrue
- BFalse
77Risk factors for the development of infective endocarditis include:
poor dental hygiene, GI procedures, prosthetic valve in situ, hx endocarditis, pacemaker, colon cancer and GU procedures- ATrue
- BFalse
78Gram positive bacteria are responsible for the majority of infective endocarditis cases
- ATrue
- BFalse
79Staph aureus is responsible for prosthetic valve-associated infective endocarditis
- ATrue
- BFalse
80Pseudomonas aeruginosa is associated with infective endocarditis in IVDU
- ATrue
- BFalse
81A patient who presents to ED with a fever and new murmur should be treated as though infective endocarditis is the diagnosis until proven otherwise
- ATrue
- BFalse
82Stroke is a potential clinical presentation for one with infective endocarditis
- ATrue
- BFalse
83Osler's nodes are associated with myocarditis
- ATrue
- BFalse
84RHS endocarditis has a very poor prognosis
- ATrue
- BFalse
85Infective endocarditis is associated with immunological phenomenon such as vasculitis and glomerulonephritis
- ATrue
- BFalse
86Jone's criteria is useful in the diagnosis of infective endocarditis
- ATrue
- BFalse
87As part of the diagnosis of infective endocarditis, 3 blood cultures need to be taken at least 1 hour apart
- ATrue
- BFalse
88The transoesphageal echo is preferred for diagnostic imaging in infective endocarditis
- ATrue
- BFalse
89Surgical, microbiology and cardiology teams are all involved in the management of infective endocarditis
- ATrue
- BFalse
90Patient with bacterial infective endocarditis should be prescribed a 4-6 week course of antibiotics
- ATrue
- BFalse
91Surgery may be required in infective endocarditis if the patient is not responding to antimicrobial therapy
- ATrue
- BFalse
92Cardiac tamponade, CCF and valve dehiscence are all complications of infective endocarditis
- ATrue
- BFalse
93Patient is septic with suspected acute infective endocarditis, and you suspect S. aureus is the causative agent, the recommended empiric treatment is Amoxicillin and Gentamicin
- ATrue
- BFalse
94Gentamicin is active against gram positive bacteria
- ATrue
- BFalse
95Prophylaxis is not advised for groups at risk of developing infective endocarditis (eg. prosthetic valve in situ)
- ATrue
- BFalse
96Myocarditis is usually caused by a viral agent
- ATrue
- BFalse
97Pericarditis can result in congestive cardiac failure
- ATrue
- BFalse
Information
- Description
- Quiz on Micro LABMED , created by Lydia McCabe on 11/12/2018.
- Author
- Lydia McCabe
- Language
- English
- Views
- 3
- History
- Created on 11 Dec 2018 · updated on 12 Dec 2018
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