Quiz
Cardiovascular System 2
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Questions in this quiz (16)
1Lungfish and Amphibian vs. Fish
- lungfish/amphibians take advantage of [blank_start]oxygen[blank_end] that is in air, the oxygen in the air is more accessible that the oxygen in water
- lungfish when oxygen level starts to drop, they extract oxygen from air pushed into their lung, needs a blood supply associated with it
- adaptation to have a [blank_start]double[blank_end] circulation
- modifications of partial or complete partition in the atrium: making the left and right atrium
The arrival of the lungs
- double circulation
- modification in [blank_start]conus[blank_end] arteriosus to separate flow
- semi-lunar valve modified to shunt deoxygenated blood to lungs (spiral valve)
[blank_start]Spiral[blank_end] valve
- there is a flap within the conus [blank_start]arteriosus[blank_end] called the spiral [blank_start]valve[blank_end], the spiral valve allow separation of flow
- deoxygenated blood comes into the heart, the flow of blood is separated due to the [blank_start]spiral[blank_end] valve
- deoxygenated blood going to the lung and oxygenated blood blood going to the body
- Aoxygen
- Bdouble
- Cconus
- DSpiral
- Earteriosus
- Fvalve
- Gspiral
2Amphibian heart
- the amphibian heart has 3 chambers: 2 [blank_start]atria[blank_end] (upper chamber) and [blank_start]1[blank_end] ventricle
- the [blank_start]spiral[blank_end] valve directs oxygenated blood entering the ventricle from the left atrium
- [blank_start]conus[blank_end] arteriosus (also called the bulbus cordis) = swelling of ventral aorta, smooth muscle
- can think of the heart as having some separation due to the [blank_start]spiral[blank_end] valve, but oxygenated blood and deoxygenated blood is mixed in the same ventricle > this is not very efficient, sending some blood that is already oxygenated back to the lungs
- very [blank_start]low[blank_end] pressure system, because both systems are connected
- Aatria
- B1
- Cspiral
- Dconus
- Espiral
- Flow
3[blank_start]Reptile[blank_end] heart
- simply 3 chambers: 2 atria, 1 ventricle
- but there is a [blank_start]septum[blank_end] this time, the heart is functionally divided, functionally divided circulation but there is a additional chamber = cavum venosum
the [blank_start]cavum[blank_end] ateriosus, cavum [blank_start]pulmonale[blank_end] and [blank_start]cavum[blank_end] venosum constitute the ventricle = these 3 chambers make up the ventricle
so in the reptile heart: the heart consists of 3 chambers: 2 atria (left and right atria) and 1 ventricle
the 1 ventricle is subdivided by the intraventricular septum making 2 main areas
- the cavum [blank_start]arteriosus[blank_end]
- the [blank_start]cavum[blank_end] pulmonale
(there is also the cavum [blank_start]venosum[blank_end], at the top of the left side)
- AReptile
- Bseptum
- Ccavum
- Dpulmonale
- Ecavum
- Farteriosus
- Gcavum
- Hvenosum
4The reptile heart cont. (2 atria, 1 ventricle)
- the cavum [blank_start]pulmonale[blank_end] receives blood from the right atrium
- the [blank_start]cavum[blank_end] arteriosus receives blood from the left atrium
Venous blood (deoxygenated blood) is collected from the body into the sinus venosus and passed into the right atrium, which pumps the blood into the [blank_start]cavum[blank_end] pulmonale, which is a section of the single ventricle, which when contracted pumps the blood via the pulmonary arteries into the lung, so the blood can be oxygenated again
Oxygenated blood returns to the heart via the pulmonary [blank_start]veins[blank_end], through the left atrium, oxygenated blood is then pumped into the cavum arteriosus section of the 1 ventricle
- the blood (oxygenated) is then pumped into the systemic circulation (body) via a THIRD area of the same 1 ventricle, known as the cavum [blank_start]venosum[blank_end] and the left and right aortic trunks
- Apulmonale
- Bcavum
- Ccavum
- Dveins
- Evenosum
5why is the reptile heart functional?
- when the 1 ventricle contracts the intraventricular septum separates, but only a [blank_start]partial[blank_end] separation > these animals can utilise this feature:
> if you stop breathing, there is [blank_start]no[blank_end] point putting blood through the lung
- can then increase [blank_start]resistance[blank_end] in the pulmonary circuit > if you decrease the diameter this increases the resistance, takes more pressure to push blood into the pulmonary circuit
- so we have a right to [blank_start]left[blank_end] shunt > reptiles are constantly doing this, because they are not breathing regularly
SO: this right to left [blank_start]shunt[blank_end], allowed by the partial seperation of the septum, also the reptiles to bypass the pulmonary circuit, so blood can just flow to the systemic system (to the [blank_start]body[blank_end]) = efficient
- Apartial
- Bno
- Cresistance
- Dleft
- Eshunt
- Fbody
6Blood flow in [blank_start]green[blank_end] turtle
- sits at the bottom of tanks, every so often the green turtle will come to the surface to breathe
- Bevan in his PHD put a mask on the surface in which the turtle breathed in when surfacing, flow meters then recorded how much was expired and how much oxygen was taken in
- measured [blank_start]blood[blank_end] flow
- from this saw high pulmonary and aortic blood flow, still blood flow in the aorta, systemic blood flow keeps going
- but there was virtually [blank_start]no[blank_end] flow in the pulmonary circulation
- the lung is devoid of [blank_start]oxygen[blank_end], has exchanged some (still some oxygen in there) just a lower level, the green turtle is using the oxygen a bit like a scuba tank
- the green turtle gradually utilises oxygen in the lung
- needs to put a lot of blood flow in lung (high blood flow in pulmonary circulation) when swimming to the surface
Whilst on the front of it, it looks like a primitive system = the two sides are connected, however, it is a system that is ideally suited to the means in which they ventilate their lungs: whilst resting they breathe [blank_start]less[blank_end] often- Agreen
- Bblood
- Cno
- Doxygen
- Eless
7Crocodile circulation on the other hand is more similar to the mammalian/avian circulation in the fact there is a completely divided ventricle
- left and right sides of the heart are still connected in the crocodile heart by the [blank_start]foramen[blank_end] of Panizza
- the foramen of [blank_start]panizza[blank_end] is a hole in the crocodile heart that connects the left and right aorta
- pressure changes in the pulmonary circuit (to the lung) can change the flow of blood in the heart
- mixing possibly takes place in the crocodile heart > but the whole of separation is to allow different pressures in the 2 systems
In order to get a constant low pressure to respiratory organ and high pressure to tissues you need separation, however in the crocodile they have this hole the foramen of [blank_start]panizza[blank_end] between the right and left aorta = problem?
- however, if you change the [blank_start]resistance[blank_end], then you can prevent mixing- Aforamen
- Bpanizza
- Cpanizza
- Dresistance
8What they have = a link between the left and right aorta = foramen of [blank_start]panizza[blank_end]
- if you change the [blank_start]resistance[blank_end] this prevents mixing
- changing the resistance in the pulmonary circulation prevents mixing
BUT more complicated
foramen of panizza = valves between aortic trunks to divert blood, allows ventricle to pump both arches when right ventricle is closed
- what happens with these animals, they sit in the water being fairly inactive waiting for prey
just like in the green turtle:
- the lungs are not utilised
- blood [blank_start]not[blank_end] pumped to lungs
- right ventricle helps pump systemic blood (right ventricle pumps blood to the [blank_start]body[blank_end]) via the right aorta
SO: when swimming to the surface you get right-left [blank_start]shunt[blank_end]
- then during submersion when the lungs are not utilised, then both ventricles pump into the [blank_start]systemic[blank_end] circulation (to the body)
- as surface: [blank_start]no[blank_end] blood is flowing into the systemic circuit from the right ventricle
- during diving: no blood flow into pulmonary circuit, it instead is going into the systemic circuit
whilst we have a fully divided heart in the [blank_start]crocodile[blank_end], its not the full hog, there is still the connection between the 2 circuits (pulmonary and systemic), they are able to bypass the pulmonary circulation
- Apanizza
- Bresistance
- Cnot
- Dbody
- Eshunt
- Fsystemic
- Gno
- Hcrocodile
9BUT EVEN MORE COMPLICATED
- found within crocodile heart there are a series of cog wheel [blank_start]valves[blank_end] = working of which is still being worked out
- linked to the ability of the animals to swift the flow between right and left sides called [blank_start]cog[blank_end] valves because look like cogs
- Acog
- Bvalves
10Mammalian and Avian heart
- 4 chambered heart: 2 atria and 2 ventricles, [blank_start]no[blank_end] longer any connection between the 2 sides of the heart, illustrates that by a completely divided heart we have essentially gone back to single circulation with 2 pumps
2 pumps: 1 pump to the lungs, 1 pump to the [blank_start]systemic[blank_end] circulation (to the body)
- so can change the pressure on one side compared to the other
- [blank_start]low[blank_end] pressure system to lung with fast flows
- high pressure system and high flow system to systemic system (to the tissues)
In the embryos the left and right atria are [blank_start]not[blank_end] separated
- Ano
- Bsystemic
- Clow
- Dnot
11Venous system = no longer have a lot of pressure
- as soon as the blood passes into the [blank_start]capillary[blank_end] network the pressure [blank_start]decreases[blank_end] therefore the propulsive force pushing blood back into the heart is very decreased
- contractions around veins help push blood back to the heart
- there are [blank_start]valves[blank_end] associated with the venous system that aid/stop the blood flowing backwards because of the low pressure
pressure differences:
- high pressure: forces [blank_start]fluid[blank_end] out of the blood and into the tissue > net driving force of fluid to leave at the capillary
fluid is squeezed out of the capillary by blood pressure
then has the pressure in the capillary networks decrease, fluid is pulled back into the capillary by [blank_start]osmotic[blank_end] pressure
- oxygen [blank_start]and[blank_end] fluid is being transferred at capillary networks
- Acapillary
- Bdecreases
- Cvalves
- Dfluid
- Eosmotic
- Fand
12Local effects on blood flow
- what happens if you do not want to send blood to the gut e.g. in a predation chase, certain body areas such as the gut do not require oxygen > this system would not work
- overall, control of blood flow is at [blank_start]arteriole[blank_end] level and not capillary level
Muscle tissue respiring
- used up oxygen, produced carbon dioxide, which [blank_start]decreases[blank_end] the pH (because it dissociates into protons and bicarbonate ions) > this local effect causes [blank_start]vasodilation[blank_end] of capillaries, the tissue needs a higher flow rate = best way to do is to increase size of vessel to increase blood flow
- so everything e.g. oxygen that has been used up is replenished
- waste material removed, and pH returns to normal
[blank_start]Vasoconstriction[blank_end] = back to normal, constant change of blood flow in capillary network
control is not at capillary level, at arteriole level
- Aarteriole
- Bdecreases
- Cvasodilation
- DVasoconstriction
13Control of [blank_start]blood[blank_end] pressure
- needs to be maintained at specific levels in order to supply the flow to the tissues, but this can change
- e.g. if you cut yourself, your blood pressure will drop
if blood pressure falls, the stretching of arteries [blank_start]decreases[blank_end], picked up, the hypothalamus releases vasopressin = water enters blood to maintain the pressure once more
- Ablood
- Bdecreases
14major respiratory pigments: all are [blank_start]metalloproteins[blank_end] (metal + protein)
- bind reversibly with oxygen at specific sites/areas
1. [blank_start]Haemoglobin[blank_end]
- [blank_start]iron[blank_end] based (changes from blue to red when oxygenated)
- most phyla use haemoglobin, including [blank_start]all[blank_end] vertebrates
2. [blank_start]Haemerythrin[blank_end]
- [blank_start]iron[blank_end] based as well
- hamerythrin colourless --> reddish/violet
3. [blank_start]Haemocyanin[blank_end]
- copper based (colourless --> blue)
- arthropods and molluscs respiratory pigment
4. [blank_start]Chlorocruorins[blank_end]
- chlorocruorins are iron based, green in colour
- fan worms and feather worms respiratory pigment
- Ametalloproteins
- BHaemoglobin
- Ciron
- Dall
- EHaemerythrin
- Firon
- GHaemocyanin
- HChlorocruorins
15Oxygen equilibrium curve
- if you put blood into a [blank_start]tucker[blank_end] cell, and then pass oxygen through at different partial pressures what you find: the amount of blood that has oxygen bound to it changes
- but does [blank_start]not[blank_end] change in a straight line
- curve produced = oxygen equilibrium curve
- Atucker
- Bnot
16Respiratory Pigment
- usually made of several [blank_start]sub[blank_end] units
- allows [blank_start]allosteric[blank_end] interactions > molecular cooperation
- binding of 1 or 2 oxygen molecules changes the shape of the haemoglobin which increases its affinity for oxygen (oxygen binds more easily)
- this allosteric interaction explains the [blank_start]sigmoidal[blank_end] shape of the oxygen equilibrium curve
In the deoxygenated force, it has a particular shape then picks up oxygen causing the molecule to change shape, making it more easy for more oxygen to attached to the second [blank_start]sub[blank_end] unit
- this then changes the shape of the molecule again > makes it easier for oxygen to attach to the 3rd subunit
- but this subsequent change of oxygen joining to the 3rd subunit, makes it [blank_start]more[blank_end] difficult for the final oxygen to attach to the 4th and final sub unit of the respiratory pigment = results in a sigmoidal shape
This relates to the partial pressure in different places in the body, the shape of the curve is important for the release of oxygen to the tissues
- as you start exercising, the partial pressure of oxygen in the tissue [blank_start]decreases[blank_end] as oxygen is used up
- releases a big proportion from the blood for the demand is greater- Asub
- Ballosteric
- Csigmoidal
- Dsub
- Emore
- Fdecreases
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- Physiology Quiz on Cardiovascular System 2, created by sophie waddington on 20/01/2019.
- Author
- sophie waddington
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- English
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