Quiz
Lipids and Membrane Structure
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Questions in this quiz (35)
1What is a triacylglycerol/triglyceride?
- AEster of three fatty acids and glycerol
- BEster of two fatty acids, glycerol and a phosphate-containing head
- CEster of two fatty acids and glycerol
- DThree fatty acids and glycerol joined by a phosphate bridge
2When naming fatty acids, we use the general formula CX:Y cis/trans-Δz. What is X?
- ANumber of carbons
- BNumber of double bonds
- CConfiguration of the double bond
- DLocation of double bond in relation to CH3 group
3When naming fatty acids, we use the general formula CX:Y cis/trans-Δz. What is Y?
- ANumber of carbons
- BNumber of double bonds
- CConfiguration of double bond
- DLocation of double bond in relation to CH3 group
4When naming fatty acids, we use the general formula CX:Y cis/trans-Δz. What is cis/trans?
- ANumber of carbons
- BNumber of double bonds
- CConfiguration of double bond
- DLocation of double bond in relation to CH3 group
5When naming fatty acids, we use the general formula CX:Y cis/trans-Δz. What is Δz?
- ANumber of carbons
- BNumber of double bonds
- CConfiguration of double bond
- DLocation of double bond in relation to the CH3 group
6What is the correct nomenclature of oleic acid?
- A18:1
- B20:4
- C16:0
- D18:0
- E18:2
7What is the correct nomenclature of arachidonic acid?
- A18:1
- B20:4
- C16:0
- D18:0
- E18:2
8What is the correct nomenclature of palmitic acid?
- A18:1
- B20:4
- C16:0
- D18:0
- E18:2
9What is the correct nomenclature of stearic acid?
- A18:1
- B20:4
- C16:0
- D18:0
- E18:2
10What is the correct nomenclature of linoleic acid?
- A18:1
- B20:4
- C16:0
- D18:0
- E18:2
11Cis-configured double bonds in fatty acids cause curved conformations which limit the ability of fatty acids to be closely packed
- ATrue
- BFalse
12What is a phospholipid?
- AGlycerol and two fatty acids linked via ester bonds with a phosphate-containing head
- BGlycerol and three fatty acids linked via ester bonds with a phosphate-containing head
- CA phosphate linked to a fatty acid
- DA phosphate and glycerol
13Apart from the basic structure, what is another feature that a phospholipid must have to be considered a phospholipid?
- APhosphate group modified by alcohol
- BPhosphate group modified by ester
- CAn unsaturated fatty acid tail
- DA sodium salt on the phosphate
14What is a glycolipid?
- AGlycerol and two fatty acids joined by ester bonds covalently bonded to a carbohydrate
- BGlycerol and three fatty acids joined by ester bonds covalently bonded to a carbohydrate
- CGlycerol and two fatty acids joined by ester bonds covalently bonded to a protein
- DGlycerol and three fatty acids joined by amide bonds covalently bonded to a lipid
15What is the glycocalyx?
- AA layer of carbohydrates on the exterior surface of the cell
- BThe portion of the glycolipid that extends from the membrane
- CThe transporter in hepatocytes that opens and increases glucose uptake in periods of hyperglycaemia
- DThe polymer unit of glucose found in animal muscle tissue
16How many carbons does sphingosine have?
- A18
- B16
- C24
- D11
17Spingosine is unsaturated
- ATrue
- BFalse
18What is the structure of the last three carbons of sphingosine?
- ACH(OH)-CH(NH2)-CH2(OH)
- BCH(NH2)-CH(OH)-CH2(NH2)
- CCH2-CH(OH)-CH3
- DCH2-CH(NH2)-CH3
19What is a ceramide?
- ASphingosine + a fatty acid chain joined by an amide bond
- BSphingosine + a fatty acid chain joined by an ester bond
- CSphingosine + a choline head
- DSphingoside + a phosphate head
20What is sphingomyelin?
- ACeramide + phosphocholine
- BCeramide + phosphate
- CCeramide + choline
- DCholine + phosphate
21How do we gain cholesterol in the body? Check all that apply
- ADe novo synthesis
- BDiet
- CInhalation
- DPhagocytosis
22What name is given to a molecule with a common structure of 3 six-membered carbon rings and 1 five-membered carbon ring?
- ASteroid
- BGlycolipid
- CGlycoprotein
- DSphingomyelin
23Why are lipid bilayers described as being asymmetrical?
- ADifferent lipid compositions on each layer
- BDifferent lipid compositions either side of the primary cilium
- CDifferent lipid compositions on membranes in different tissues
- DPhospholipids are of different sizes
24An increase in SCFA in the cell membrane reduces Van der Waals interactions between fatty acids and increases fluidity
- ATrue
- BFalse
25Unsaturated fatty acids have 'kinks' which reduce Van der Waals interactions between fatty acids and increase fluidity
- ATrue
- BFalse
26High cholesterol content restricts the movement of polar phospholipid heads and buffers temperature changes - this decreases the fluidity of the membrane
- ATrue
- BFalse
27What name is given to a microdomain within the membrane which is highly concentrated with cholesterol, transmembrane proteins and glycosphingolipids?
- ALipid raft
- BCholesterol raft
- CLipid island
- DSphingo island
28Which membrane protein is embedded within the lipid bilayer in a transmembrane fashion?
- AIntegral/intrinsic
- BAnchored
- CPeripheral/extrinsic
29Which membrane protein is anchored to the membrane by covalent bonds with fatty acids either in the bilayer directly or by glycolipids?
- AIntegral/intrinsic
- BAnchored
- CPeripheral/extrinsic
30Which membrane proteins attach to the membrane surface via ionic interactions with integral proteins or the polar head groups of phospholipids?
- AIntegral/intrinsic
- BAnchored
- CPeripheral/extrinsic
31Which types of membrane protein will be removed by high salt/urea? Check all that apply
- APeripheral
- BAnchored
- CIntegral
32Which types of membrane protein will be removed by detergent? Check all that apply
- APeripheral
- BAnchored
- CIntegral
33Which types of membrane protein will be removed by phospholipases?
- APeripheral
- BAnchored
- CIntegral
34When we use high salt/urea to remove membrane proteins from the bilayer, the high salt content breaks the [blank_start]hydrogen[blank_end] bonds between the proteins and the surface of the membrane. This in turn will [blank_start]denature[blank_end] the proteins themselves. Therefore, we may not be able to determine the [blank_start]function[blank_end] of a protein removed by this method but we will be able to [blank_start]quantify[blank_end] how much is present within the membrane.
- Ahydrogen
- Bdenature
- Cfunction
- Dquantify
35Detergents are [blank_start]amphipathic[blank_end] molecules with the ability to manipulate hydrophobic-[blank_start]hydrophilic[blank_end] interactions among biological molecules. At high concentrations, they penetrate between the bilayer and form [blank_start]micelles[blank_end] containing phospholipids and protein. The [blank_start]protein[blank_end] can then be purified from the sample. The micelles thermodynamically [blank_start]stabilise[blank_end] the internal material whilst maintaining [blank_start]hydrophilia[blank_end] on the outside. Thus, detergents solubilise their contents.
- Aamphipathic
- Bhydrophilic
- Cmicelles
- Dprotein
- Ehydrophilia
- Fstabilise
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- Cell Biology and Signalling Quiz on Lipids and Membrane Structure, created by Charlotte Jakes on 02/11/2019.
- Author
- Charlotte Jakes
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- English
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