326320
Description
Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
over 10 years ago
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Question 1
Question
Epidermal Growth Factors are 53aa long, with an Mr of 40,000
Answer
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True
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False
Question 2
Question
What happens when you increase ornithine carboxylase and polyamine concentrations?
Answer
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Cell division increases
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Cell division decreases
Question 3
Question
In general effects ( inc glucose/aa transport and inc Na/K ATPase activity) what hormone are growth factors most like?
Answer
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Insulin
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Glucagon
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Vasopressin
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NO
Question 4
Question
Increase Na+/H+ pump activity causes what?
Answer
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Alkylysation of the cytoplasm
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Inc. DNA synthesis/mitosis
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Inc protein production
Question 5
Question
How is tyrosine kinase kept inactive when a ligand is not bound?
Answer
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The activation lip hides the active site
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The active site is phosphorylated and inactive
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A pseudosubstrate is bound
Question 6
Question
What form does inactive tyrosine kinase stay in?
Answer
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Monomer
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Dimer
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Multimeric group
Question 7
Question
What effect does ligand binding have to tyrosine kinase?
Answer
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Partial activation
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Dimerisation
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Monomerisation
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Full activation
Question 8
Question
Once the activation lip is phosphorylated, what happens?
Answer
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Phosphorylation continues of tyrosine kinase
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Becomes fully active
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Becomes partially active
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Proteins bind to phosphorylated areas
Question 9
Question
Which of the following binds to phosphorylated tyrosine kinase?
Answer
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GRB2
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RAs
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GEF
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