Quiz
Clinical Immunology - Autoimmunity MCQs and Fill in the blanks
This quiz has question types that open in the usual player.
Questions in this quiz (25)
1Autoantibodies are normally present in the repertoire of the immune
system:- ATrue
- BWrong
2The functions of the immune system do not include distinguishing one's own from foreign antigens:
- ATrue
- BIncorrect
3Antinuclear antibodies (ANA) are positive in most patients with
systemic lupus erythematosus (SLE):- AYes
- BNo
4Sm and RNP are part of the group of extractable nuclear antigens that induce the formation of ANA:
- AYes
- BNo
5Autoantibodies to cytoplasmic antigens of neutrophils ANCA are not detected in Wegener's granulomatosis and microscopic polyangiitis:
- ATrue
- BIncorrect
6Which of the following mechanisms are involved in the development of autoimmune diseases
- AModification of its own antigen and its recognition as foreign to the immune system
- BDeficiency of suppressor T cells
- CAntigenic mimicry due to infection by microorganisms with cross reactive antigens
- DRelease of isolated (sequestered) antigens
- EAll answers are correct
7Systemic lupus erythematosus
- AAs caused by mutations in DNA
- BManifests itself with many symptoms and affects many organs
- CIs an example of a T-cell mediated disease
- DIs the result of the formation of immune complexes
- EAll answers are correct
8Vascular inflammation and glomerulonephritis induced by
autoantibodies are characteristic of:- AChronic granulomatous disease
- BAngioneurotic edema
- CSystemic lupus erythematosus
- DHemolytic anemia
- EThere is no correct answer
9Autoimmune hemolytic anemias occur most often by the type
of:- AAnaphylactic hypersensitivity reactions
- BCytotoxic hypersensitivity reactions
- CImmunocomplex hypersensitivity reactions
- DCell-mediated hypersensitivity reactions
- EThere is no correct answer
10Lymphocytic infiltration of the thyroid gland is characteristic
of:- ATuberculosis
- BPneumonia
- CHemolytic anemia
- DHashimoto's thyroiditis
- EThere is no correct answer
11The rheumatoid factor in the serum of a patient with rheumatoid arthritis is most often:
- AIgM reacting with an Fc fragment of endogenous IgG
- BIgM reacting with a Fab-fragment of IgG
- CIgE reacting with allergens
- DAntibody against DNA
- EAcute phase protein
12Which of the following methods is not used to detect rheumatoid factor in serum?
- ALatex agglutination
- BIndirect immunofluorescence
- CELISA
- DImmunoturbidimetry
- ENephelometry
13The following are used for ANA research:
- AThe direct immunofluorescence test
- BThe indirect immunofluorescence test
- CELISA and / or immunoblot
- DComplement fixation reaction
- ENeutralization
14Which of the following substrates are most commonly used for the determination of ANA with indirect immunofluorescence:
- ACryostatic section of rat liver
- BCryostatic section of rat kidney
- CCryostat section of rat stomach
- DHEp2 cell line
- EThere is no correct answer
15To prove autoimmune diseases of the thyroid gland are
examined- AAntinuclear antibodies
- BAnti-thyroglobulin antibodies
- CAnti-neutrophil cytoplasmic antibodies
- DAntibodies against thyroid peroxidase
- EAntibodies against pancreatic islet cells
16Rheumatoid arthritis develops by the mechanism
of [blank_start]IMMUNOCOMPLEX[blank_end] allergic reactions.- AIMMUNOCOMPLEX
17Autoantibodies to double-stranded DNA are found mainly in patients with [blank_start]SLE[blank_end].
- ASLE
18Patients with insulin-dependent diabetes mellitus usually have
antibodies to the [blank_start]ISLAND CELLS[blank_end] OF [blank_start]THE PANCREAS[blank_end].- AISLAND CELLS
- BTHE PANCREAS
19Anti-LKM, ANA and anti-smooth muscle antibodies are important studies in the diagnosis of [blank_start]AUTOIMMUNE HEPATITIS[blank_end].
- AAUTOIMMUNE HEPATITIS
20Detection of HLA-B27 antigen assists in the diagnosis
of [blank_start]ANKYLOSING SPONDYLITIS[blank_end].- AANKYLOSING SPONDYLITIS
21Antiphospholipid syndrome?
Answer: [blank_start]Anticardiolipin antibodies[blank_end]- AAnticardiolipin antibodies
22Myasthenia gravis?
Answer: [blank_start]Antibodies[blank_end] against [blank_start]acetylcholine receptors[blank_end]- AAntibodies
- Bacetylcholine receptors
23 Gluten enteropathy?
Answer: [blank_start]Antigliadin antibodies[blank_end]- AAntigliadin antibodies
24Pernicious anemia?
Answer: [blank_start]Autoantibodies[blank_end] against [blank_start]parietal[blank_end] cells of the [blank_start]stomach[blank_end] and [blank_start]intrinsic factor[blank_end]- AAutoantibodies
- Bparietal
- Cstomach
- Dintrinsic factor
25Primary biliary cirrhosis?
Answer: [blank_start]Antimitochondrial antibodies[blank_end]- AAntimitochondrial antibodies
Information
- Description
- A2 clinical immunology Quiz on Clinical Immunology - Autoimmunity MCQs and Fill in the blanks, created by suyog gurung on 17/06/2022.
- Author
- suyog gurung
- Language
- English
- Views
- 40
- History
- Created on 17 Jun 2022 · updated on 17 Jun 2022
- Tags
- Rating
- No ratings yet Rate this quiz