Neurocognitive Disorders Test A

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Professional Clinical Neuropsychology (Neurocognitive Disorders) Quiz on Neurocognitive Disorders Test A, created by Eunho Lee on 17/01/2016.
Eunho Lee
Quiz by Eunho Lee, updated more than 1 year ago
Eunho Lee
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Question 1

Question
The essential feature of the DSM-5 diagnosis of delirium is a disturbance in attention/awareness and in cognition that develops over a short period of time, represents a change from baseline, and tends to fluctuate in severity during the course of a day. Which of the following additional conditions must apply?
Answer
  • There must be laboratory evidence of an evolving dementia.
  • The disturbance must be associated with a disruption of the sleep-wake cycle.
  • The disturbance must not occur in the context of a severely reduced level of arousal, such as coma.
  • The disturbance must be a direct physiological consequence of a substance use disorder.
  • The disturbance must not be superimposed on a preexisting neurocognitive disorder.

Question 2

Question
A 79-year-old woman with a history of depression is being evaluated at a nursing home for a suspected urinary tract infection. She is easily distracted, perseverates on answers to questions, asks the same question repeatedly, is unable to focus, and cannot answer questions regarding orientation. The mental status changes evolved over a single day. Her family reports that they thought she “wasn’t herself” when they saw her the previous evening, but the nursing report this morning indicates that the patient was cordial and appropriate. What is the most likely diagnosis?
Answer
  • Major depressive disorder, recurrent episode.
  • Depressive disorder due to another medical condition.
  • Delirium.
  • Major depressive disorder, with anxious distress.
  • Obsessive-compulsive disorder.

Question 3

Question
Which of the following is not a diagnostic criterion, feature, or marker of major or mild neurocognitive disorder with Lewy bodies (NCDLB)?
Answer
  • Concurrent symptoms of rapid eye movement (REM) sleep behavior disorder.
  • High striatal dopamine transporter uptake in basal ganglia demonstrated by single-photon emission computed tomography (SPECT) or positron emission tomography (PET) imaging.
  • Low striatal dopamine transporter uptake in basal ganglia demonstrated by SPECT or PET imaging.
  • Severe neuroleptic sensitivity.
  • Insidious onset and gradual progression.

Question 4

Question
The diagnostic criteria for neurocognitive disorder (NCD) due to HIV infection include fulfillment of criteria for major or mild NCD and documented infection with human immunodeficiency virus (as confirmed by established laboratory methods). Which of the following is a prominent feature of NCD due to HIV infection?
Answer
  • Impairment in executive functioning.
  • Conspicuous aphasia.
  • Significant delusions and hallucinations at onset of the disorder.
  • Marked difficulty with recall of learned information.
  • Rapid progression to profound neurocognitive impairment.

Question 5

Question
Which of the following features characterizes alcohol-induced major or mild neurocognitive disorder, amnestic-confabulatory type?
Answer
  • Amnesia for new information and confabulation.
  • Seizures.
  • Amnesia for previously learned information and downward gaze paralysis.
  • Aphasia.
  • Anosognosia and apraxia.

Question 6

Question
Depression, irritability, anxiety, obsessive-compulsive symptoms, and apathy are frequently associated with Huntington’s disease and often precede the onset of motor symptoms. Psychosis more rarely precedes the onset of motor symptoms. Which of the following is a core feature of major or mild neurocognitive disorder due to Huntington’s disease?
Answer
  • Progressive cognitive impairment with early changes in executive function.
  • Prominent early memory impairment, mostly affecting short-term memory.
  • Psychosis in the early stages, with marked olfactory hallucinations.
  • Voluntary jerking movements.
  • Diminished hearing and smell.

Question 7

Question
Major or mild neurocognitive disorder (NCD) due to prion disease encompasses NCDs associated with a group of subacute spongiform encephalopathies caused by transmissible agents known as prions. What is the most common prion disease?
Answer
  • Creutzfeldt-Jakob disease.
  • Wernicke-Korsakoff syndrome.
  • Bovine spongiform encephalopathy.
  • Huntington’s disease.
  • Neurosyphilis.

Question 8

Question
Major and mild neurocognitive disorders (NCDs) exist on a spectrum of cognitive and functional impairment. Which of the following constitutes an important threshold differentiating the two diagnoses?
Answer
  • Whether or not the individual is concerned about the decline in cognitive function.
  • Whether or not there is impairment in cognitive performance as measured by standardized testing or clinical assessment.
  • Whether or not the cognitive impairment is sufficient to interfere with independent completion of activities of daily living.
  • Whether or not the cognitive deficits occur exclusively in the context of a delirium.
  • Whether or not the cognitive deficits are better explained by another mental disorder.

Question 9

Question
A 68-year-old semiretired cardiologist with responsibility for electrocardiogram (ECG) interpretation at his community hospital is referred by the hospital’s Employee Assistance Program for clinical evaluation because of concerns expressed by other clinicians that he has been making many mistakes in his ECG interpretations over the past few months. The patient discloses symptoms of persistent sadness since the death of his wife 6 months prior to the evaluation, with frequent thoughts of death, trouble sleeping, and escalating usage of sedative-hypnotics and alcohol. He has some trouble concentrating, but he has been able to maintain his household, pay his bills, shop, and prepare meals by himself without difficulty. He scores 28/30 on the Mini-Mental State Examination (MMSE). Which of the following would be the primary consideration in the differential diagnosis?
Answer
  • Major neurocognitive disorder (NCD).
  • Mild NCD.
  • Adjustment disorder.
  • Major depressive disorder.
  • No diagnosis.

Question 10

Question
In a patient with mild neurocognitive disorder (NCD), which of the following would distinguish probable from possible Alzheimer’s disease?
Answer
  • Evidence of a causative Alzheimer’s disease genetic mutation from either genetic testing or family history.
  • Clear evidence of decline in memory and learning.
  • Steadily progressive, gradual decline in cognition, without extended plateaus.
  • No evidence of mixed etiology.
  • Onset after age 80.

Question 11

Question
The only way that mild NCD due to probable Alzheimer’s disease can be diagnosed is if there is evidence of a causative Alzheimer’s disease genetic mutation from either genetic testing or family history. Mild NCD due to possible Alzheimer’s disease is diagnosed on the basis of the presence of all of the clinical criteria described in options B–D above. Age at onset is not a diagnostic criterion.
Answer
  • Major or mild NCD due to Alzheimer’s disease.
  • Major or mild NCD with Lewy bodies.
  • Major or mild vascular NCD.
  • Behavioral-variant major or mild frontotemporal NCD.
  • Language-variant major or mild frontotemporal NCD.

Question 12

Question
A previously healthy 67-year-old man, who is experiencing an acute change in mental status, is brought to the emergency department by his family. There is no evidence in the initial history, physical examination, and laboratory studies to indicate substance intoxication or withdrawal, or to suggest another medical problem as the cause of his altered mental state. Over the course of 1 hour of observation, his level of alertness varies from alert but distractible, with apparent auditory and visual hallucinations, to somnolent; he has difficulty sustaining attention to an examiner, and he cannot perform simple tasks such as serial subtractions or spelling words backwards. What is the most appropriate diagnosis?
Answer
  • Delirium.
  • Delirium due to another medical condition.
  • Delirium due to substance intoxication.
  • Delirium due to multiple etiologies.
  • Unspecified delirium.

Question 13

Question
Which of the following symptoms is not likely to be observed in a patient suffering from Alzheimer's disease?
Answer
  • memory impairment
  • aggressive behavior
  • a language impairment
  • personality change
  • executive dysfunction

Question 14

Question
The initial symptoms of a specific type of dementias (to which Pick's disease belongs) include language impairment and personality changes, rather than memory problems. Which type of dementia is described here?
Answer
  • frontal dementias
  • fronto-temporal dementias
  • cortical dementias
  • fronto-parietal dementias
  • Parkinson's disease

Question 15

Question
Which of the following is NOT likely to be observed in patients suffering from Huntington's disease?
Answer
  • disturbed executive functioning
  • impaired spatial processing
  • depression
  • a highly elevated concentration of cholinergic and GABAergic neurons
  • decreased speed of information processing

Question 16

Question
다음 보기 중에서 치매임상평가척도(Clinical Dementia Rating, CDR)에서 평가하는 영역에 해당하는 것을 모두 고르시오.
Answer
  • 기억력
  • 지남력
  • 위생과 몸치장
  • 주의집중능력
  • 사회활동

Question 17

Question
치매임상평가척도(Clinical Dementia Rating, CDR)에 대한 설명 중 틀린 것을 고르시오.
Answer
  • CDR은 구조화된 면담형식으로 이루어져 있다.
  • 치매가 아닌 신체적 또는 정신과적 문제로 인한 기능장애는 CDR에서 평가하는 기능장애에 포함하지 않는다.
  • 전반적 CDR 단계를 결정할 때, 가장 중요한 영역은 <기억력>이다.
  • CDR 시행에 필요한 시간은 대략 40여분이다.
  • CDR 1은 경도의 치매에 해당한다.

Question 18

Question
보호자는 K씨의 문제해결능력이 전반적으로 이전에 비하여 매우 좋지 않다고 진술하였다. 세부적으로는, 간단한 돈 계산이나 돈관리, 간단한 업무처리에 심한 장애를 나타내고 있으며, 위급한 일에 대처하는 능력도 현저히 저하되어 있었다. 사회생활이나 대인관계에서도 적절히 행동하는 것이 매우 어렵다고 한다. 그러나 상황이나 설명에 대해 이해하는 것의 어려움은 상대적으로 경미하였으며, 단순한 계산은 가능하였다. K씨의 판단력 및 문제해결능력에 대한 CDR 등급으로 적절한 것은?
Answer
  • CDR 1
  • CDR 2
  • CDR 3
  • CDR 4
  • CDR 0.5

Question 19

Question
전반적퇴화척도(Global Deterioration Scale, GDS)에 대한 설명 중 틀린 것을 고르시오.
Answer
  • 치료의 경과나 예후를 평가하는데 유용하다.
  • 적용에 있어 간편하고 소요시간이 짧다.
  • 환자의 교육 수준에 영향을 받는다.
  • GDS 6단계는 CDR 2단계와 유사하다.
  • 혈관성 치매 환자를 대상으로 사용할 수 있다.

Question 20

Question
MMSE에 대한 다음의 설명 중 틀린 것을 고르시오.
Answer
  • 전 세게적으로 가장 널리 사용되는 치매 선별검사이다.
  • 중등도 혹은 심한 수준의 치매를 탐지하는 데에 신뢰도와 타당도가 부족하다.
  • 치매를 확진하거나 치매의 유형을 구별할 수는 없다.
  • 반복적인 측정으로 인지기능의 변화를 관찰할 수 있다.
  • 실시에 필요한 소요시간은 대략 10분 이하이다.

Question 21

Question
한국형 간이정신상태검사(K-MMSE)는 총 30문항으로 이루어져 있다.
Answer
  • True
  • False

Question 22

Question
MMSE의 수행성적은 연령과 교육 수준에 크게 영향받지 않는다.
Answer
  • True
  • False

Question 23

Question
강연욱 등(1997)이 국내 치매환자들을 대상으로 수행한 연구결과에 따르면 알츠하이머형 치매 환자들은 혈관성 치매 환자들에 비해 지남력과 기억회상 과제에서 더 낮은 점수를 받았다.
Answer
  • True
  • False

Question 24

Question
IADL에 대한 다음 설명 중 틀린 것을 고르시오.
Answer
  • IADL의 수행 정도는 성별에 영향을 어느 정도 받는다.
  • IADL은 치매 환자의 인지기능 변화와 밀접한 관련이 있다.
  • IADL은 환자의 가족 뿐만 아니라 간병인(보호자)과의 면담을 통하여 실시할 수 있다.
  • IADL은 최근 6개월 간 환자의 상태를 고려햐여 응답한다.
  • IADL은 초기치매뿐만 아니라 말기치매까지도 치매의 진행 정도를 평가하는 데 유용하게 사용할 수 있다.

Question 25

Question
NPI를 통한 평가는 보호자의 주관적 요소가 많이 개입되어 실제 환자가 경험하는 증상의 심각도나 고통 정도를 정확하게 반영한다고 볼 수는 없다.
Answer
  • True
  • False
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