Immunology Quiz Personal MedStudent

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Immunology Quiz Personal

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Question 1

Question
A blood group has both A and B antigens but no antibodies, It is
Answer
  • B
  • AB
  • O
  • A

Question 2

Question
A compound formed in an organism for inhibiting growth of another organism is
Answer
  • Antigen
  • Antibody
  • Antibiotic
  • Antiallergic

Question 3

Question
A disease due to allergic reaction is
Answer
  • Enteric fever
  • Yellow fever
  • Hay fever
  • Trench fever

Question 4

Question
Which is involved in body defense?
Answer
  • Neutrophils
  • Macrophages
  • Lymphocytes
  • All the above

Question 5

Question
A doctor suggested to a couple not to have more than one child because of
Answer
  • Rh+ male Rh- female
  • Rh- male Rh+ female
  • Rh+ male Rh+ female
  • Rh- male Rh- female

Question 6

Question
A molecule that produces an immune response is
Answer
  • Antigen
  • Antibody
  • Carcinogen
  • Mutagen

Question 7

Question
A noninfectious unnatural and unusual reaction to a substance or condition is
Answer
  • Immunity
  • Allergy
  • Infection
  • Toxin

Question 8

Question
A person is injected with gammaglobulin against hepatitis B. It is
Answer
  • Artificially acquires passive immunity
  • Artificially acquires active immunity
  • Naturally acquires active immunity
  • Naturally acquires passive immunity

Question 9

Question
Acquired immunity as developed after vaccination or infection is found in
Answer
  • Vertebrates only
  • Invertebrates as well as vertebrates
  • Plants
  • All the above

Question 10

Question
Acquired immunity is found in
Answer
  • Invertebrates
  • Vertebrates
  • Some invertebrates
  • Both vertebrates and invertibrates

Question 11

Question
Active immunity is due to
Answer
  • Suppressor T-cells
  • killer T-cells
  • Memory cells
  • Helper T-cells

Question 12

Question
Active immunity means
Answer
  • Resistance developed before disease
  • Resistance developed after disease
  • Increased heart beat
  • Increased flow of blood

Question 13

Question
AIDS is caused by
Answer
  • RNA virus
  • DNA virus
  • Herpes virus
  • Hepatitis virus

Question 14

Question
An example of innate immunity is
Answer
  • T-lymphocytes
  • B-lymphocyte
  • Neutrophils
  • Thyroid cells

Question 15

Question
An insect bite may result in inflammation of that spot. It is triggered by alarm chemicals such as
Answer
  • Histamine and dopamine
  • Histamine and kinins
  • Interferon and opsonin
  • Interferons and histones

Question 16

Question
An Rh- individual receives Rh+ blood. The recipient becomes
Answer
  • Sterlite
  • Dead
  • No reaction
  • Isoimmunised

Question 17

Question
Which of the following are secondary lymphoid organs?
Answer
  • Spleen
  • Lymph Nodes
  • Thymus
  • Bone Marrow
  • Lymph Vessels

Question 18

Question
IgG consists of
Answer
  • 2 light chains and two heavy chains joined by di-sulphide bond (H2L2)
  • 2 light chains and two heavy chains joined by hydrogen bond (H2L2)
  • 2 light chains and a heavy chain joined by di-sulphide bond (H1L2)
  • a light chain and two heavy chains joined by di-sulphide bond (H2L1)

Question 19

Question
Which is the Ig that first reaches the site of infection?
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 20

Question
Which is the largest Ig?
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 21

Question
Which of the following statements are true regarding IgM?
Answer
  • IgM is a pentamer and is the largest Ig and called as ‘natural antibody’
  • IgM exists as monomer on B-cell surface
  • IgM is involved in early primary immune response
  • all of these

Question 22

Question
Which of the following statements are true?
Answer
  • IgM is involved in primary immune response
  • IgG is involved in primary immune response
  • Both IgM and IgG are involved in primary immune response
  • IgG is involved only in secondary immune response

Question 23

Question
The antibody present in secretions like tears, saliva, colostrum is
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 24

Question
The primary Ig of exocrine secretions is
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 25

Question
Antibodies are:
Answer
  • proteins
  • glycoproteins
  • carbohydrates
  • nucleic acid

Question 26

Question
The antigen binding site on an antibody is called:
Answer
  • endotope
  • paratope
  • epitope
  • antitope

Question 27

Question
An antibody has
Answer
  • 2 Fab regions and an Fc region
  • an Fab region and an Fc region
  • 2 Fab regions and 2 Fc regions
  • many Fab regions and many Fc regions

Question 28

Question
The hypervariable region resides in the
Answer
  • N terminal region of light chain
  • N-terminal region of light and heavy chain
  • C-terminal region of light chain
  • C-terminal region of light chain and heavy chain

Question 29

Question
Fab stands for
Answer
  • fragment antibody binding
  • fragment antigen binding
  • fragment antibody or antigen binding
  • fragment affinity binding

Question 30

Question
Which of the following statement is true regarding Fc region?
Answer
  • fragment crystalisation and is the constant region
  • fragment constant and is the variable region
  • fragment crystalisation and is the variable region
  • fragment crystalisation and has both variable and constant region

Question 31

Question
Fab region:
Answer
  • has a hypervariable region that binds with antibody
  • has a hypervariable region that binds with antigen
  • has a hypervariable region that binds with other immune cells
  • all of these

Question 32

Question
Fc region is involved in
Answer
  • cell surface receptor binding
  • complement activation
  • determining diffusivity of antibody molecule
  • all of these

Question 33

Question
The ability of antigen to stimulate antibody production is called
Answer
  • Affinity
  • Antigenicity
  • Elicitation
  • none of these

Question 34

Question
Clearance of antigens by antibodies involve
Answer
  • neutralization and agglutination
  • opsonisation and complement activation
  • precipitation
  • all of these

Question 35

Question
The two identical light chains of an antibody belongs to
Answer
  • kappa only
  • lambda only
  • lambda or kappa
  • none of these

Question 36

Question
Antigens can be
Answer
  • proteins
  • carbohydrates
  • nucleic acids
  • all of these

Question 37

Question
A molecule that reacts with specific antibody but is not immunogenic by itself is called
Answer
  • carrier
  • antigen
  • hapten
  • immunogen

Question 38

Question
Haptens are immunogenic upon binding covalently to a carrier protein how?
Answer
  • covalently to a carrier protein
  • covalently to an antibody
  • covalently to a paratope
  • none of these

Question 39

Question
Haptens cannot activate T cell or B cells due to:
Answer
  • its low molecular weight antigens arbuscules
  • its inability to bind to MHC
  • both a and b
  • none of these

Question 40

Question
Which of the following is a hapten?
Answer
  • Cyanide
  • Paracetamol
  • Penicillin
  • None of these

Question 41

Question
An incomplete antigens
Answer
  • are also called as haptens
  • are immunogenic upon binding covalently to a carrier protein
  • cannot induce antibody production by itself
  • all of the above

Question 42

Question
The second most abundant Ig is
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 43

Question
The most effective Ig is:
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 44

Question
IgM is a
Answer
  • pentamer with 10 antigen binding sites
  • tetramer with 8 antigen binding sites
  • monomer with 2 antigen binding sites
  • dimer with 4 antigen binding sites

Question 45

Question
The Ig that mediates allergic reaction is
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 46

Question
The Ig involved in host defence against parasitic infection (helminths)
Answer
  • IgM
  • IgG
  • IgA
  • IgE

Question 47

Question
The bonds involved in antigen-antibody interactions are
Answer
  • weak hydrogen bonds and vanderwalls forces
  • strong covalent bonds
  • strong di- sulphide bonds
  • all of these

Question 48

Question
Which of the following statement is true?
Answer
  • all immunogens are antigens but all antigens are not immunogens
  • all immunogens are antigens and all antigens are immunogens
  • all immunogens are not antigens but all antigens are immunogens
  • all immunogens are proteins and all proteins are immunogens

Question 49

Question
Which of the statements are true regarding antigen?
Answer
  • generally self-molecules and molecules with low molecular weight are non-immunogenic
  • an antigen generally has many epitopes
  • heteropolymers are more immunogenic than homopolymers
  • all of these

Question 50

Question
The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
Answer
  • transplantation
  • replacement therapy
  • repair and replacement
  • none of these

Question 51

Question
The transfer of individuals own tissue to another part of the body is called
Answer
  • autograft
  • xenograft
  • allograft
  • syngeneic graft

Question 52

Question
The transfer of tissue between genetically identical individuals (like twins) is called
Answer
  • autograft
  • xenograft
  • allograft
  • syngeneic graft

Question 53

Question
The transfer of tissue between individuals of different species is called
Answer
  • autograft
  • xenograft
  • allograft
  • syngeneic graft

Question 54

Question
The transfer of tissue between genetically different individuals of same species is called
Answer
  • autograft
  • xenograft
  • allograft
  • syngeneic graft

Question 55

Question
Which of the following has the maximum transplantation success rate?
Answer
  • autograft
  • xenograft
  • allograft
  • syngeneic graft

Question 56

Question
The major molecules responsible for rejection of transplant is
Answer
  • B cells
  • T cells
  • MHC molecule
  • Antibodies

Question 57

Question
Which of the following statements are true regarding transplantation?
Answer
  • The compatibility of MHC proteins of donor and recipient will determine the success of transplantation
  • MHCs are just like fingerprints and all nucleated cells possess this fingerprint
  • The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.
  • all of these

Question 58

Question
In humans, MHC is called as
Answer
  • Human MHC
  • Homo MHC
  • Human leucocyte antigen (HLA)
  • All of the above

Question 59

Question
The genes for HLA proteins are clustered in the major histocompatibility complex located
Answer
  • on the short arm of chromosome 6
  • on the long arm of chromosome 6
  • on the short arm of chromosome 10
  • on the long arm of chromosome 10

Question 60

Question
The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donor and recipient is called
Answer
  • MHC matching
  • MHC typing
  • tissue typing
  • blood HLA test

Question 61

Question
MHC class I is a cell surface molecule present on
Answer
  • B cells
  • All nucleated cells
  • APCs
  • T cells

Question 62

Question
MHC class II is a cell surface molecule present on (most correct ans.)
Answer
  • B cells
  • All nucleated cells
  • APCs
  • T cells

Question 63

Question
Which of the following statements are true regarding complement activation?
Answer
  • lysis of pathogen, tumor cells and allografts
  • production of mediators that attracts neutrophils to the site of inflammation
  • opsonization
  • all of these

Question 64

Question
Complement system is involved in
Answer
  • specific defence
  • non-specific defence
  • both a and b
  • none of these

Question 65

Question
Allergy to penicillin is an example of
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 66

Question
Type IV hypersensitivity is also called as:
Answer
  • immediate hypersensitivity
  • delayed hypersensitivity
  • cytotoxic hypersensitivity
  • immune complex hypersensitivity

Question 67

Question
The most common class of antibody involved in type II hypersensitivity is
Answer
  • IgG
  • IgM
  • IgE
  • IgD

Question 68

Question
T helper cell mediated hypersensitivity is:
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 69

Question
Type III hypersensitivity is triggered by:
Answer
  • Mast cells and IgE
  • K cells and IgG
  • Deposition of antigen antibody complexes
  • Th cells

Question 70

Question
Autoimmune hemolytic anemia (AHA) is an example of
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 71

Question
K cells and IgG mediated hypersensitivity is
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 72

Question
Antibody dependent cytotoxicity is associated with
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 73

Question
Allergies to sea foods, eggs etc is an example of
Answer
  • Type I hypersensitivity
  • Type II hypersensitivity
  • Type III hypersensitivity
  • Type IV hypersensitivity

Question 74

Question
Humoral immunity is mediated by
Answer
  • B cells
  • macrophages
  • both a and b
  • phagocytes

Question 75

Question
Humoral immunity is also called as
Answer
  • antibody mediated immunity
  • non-specific immune response
  • antigen mediated immunity
  • all of these

Question 76

Question
B cell has receptor on its surface which is
Answer
  • monomeric IgM
  • dimeric IgM
  • monomeric IgG
  • B cell receptor

Question 77

Question
B cells upon activation by antigens
Answer
  • undergo clonal expansion followed by clonal selection
  • divides continuously
  • undergo clonal selection followed by clonal expansion
  • secrete antibodies

Question 78

Question
B cells differentiates to form
Answer
  • plasma cells only
  • effector cells only
  • plasma cells and memory B cells
  • none of these

Question 79

Question
Which of the following statement is incorrect regarding plasma cells?
Answer
  • Plasma cells are the effector cells
  • Plasma cells secretes antibodies
  • The precursor of plasma cell is B cell
  • Plasma cell has surface receptors

Question 80

Question
Origin and maturation of B cells takes place at
Answer
  • lymph nodes
  • bone marrow
  • thymus
  • spleen

Question 81

Question
The function of memory B cell is
Answer
  • antibody production
  • immunologic memory
  • regulated antibody production
  • none of these

Question 82

Question
Generally antibodies produced against a pathogen is
Answer
  • monoclonal
  • homogenous
  • polyclonal
  • all of same specificity

Question 83

Question
Antibodies produced by plasma cells are
Answer
  • specific
  • produced against the epitope that triggered B cell activation
  • both a and b
  • diverse

Question 84

Question
Antibodies clear out antigens by
Answer
  • neutralization
  • precipitation
  • agglutination
  • all of these

Question 85

Question
Antibodies are
Answer
  • opsonins
  • lipoproteins
  • serum phagocytes
  • none of these

Question 86

Question
Any substance that promotes phagocytosis of antigens by binding to them are called as
Answer
  • interleukins
  • macrophages
  • phagocytes
  • opsonins

Question 87

Question
The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called
Answer
  • clonal expansion
  • monoclonal selection
  • clonal proliferation
  • clonal selection

Question 88

Question
The specific targeted responses constitute the third line of defense in response to an infectious agent and is called as
Answer
  • third line of defence
  • adaptive immunity
  • acquired immunity
  • all of these

Question 89

Question
The characteristics of adaptive immunity include
Answer
  • specificity
  • immunologic memory
  • discrimination of self from non self molecules
  • all of these

Question 90

Question
Which of the cells are involved in adaptive immunity?
Answer
  • B cells and T cells
  • B cells only
  • T cells only
  • macrophages and NK cells

Question 91

Question
T cell mediates
Answer
  • humoral immunity
  • non-specific defence
  • cell mediated immunity
  • none of these

Question 92

Question
The ratio of T cells to B cells is
Answer
  • 3:1
  • 1:3
  • 1:1
  • 1:2

Question 93

Question
T cells and B cells are originated in
Answer
  • spleen
  • thymus
  • bone marrow
  • lymph nodes

Question 94

Question
Injection of anti-venom against snake bite is an example of
Answer
  • active immunity
  • passive immunity
  • non-specific immunity
  • phagocytic immunity

Question 95

Question
Which of the following statements are true regarding adaptive immunity?
Answer
  • prior exposure to antigen is essential
  • prior exposure to antigen is not essential
  • it is a non-specific defence mechanism
  • macrophages are the major cells involved

Question 96

Question
Active immunity involves
Answer
  • contact with foreign antigens
  • immunologic memory
  • slow primary response
  • all of the above

Question 97

Question
Active immunity is produced by
Answer
  • clonal selection
  • clonal expansion
  • both a and b
  • all of these

Question 98

Question
Cells involved in adaptive immunity or acquired immunity or specific defense include
Answer
  • T cells
  • B cells
  • Antigen presenting cells
  • All of these

Question 99

Question
Plasma cells are secreted by
Answer
  • T cells
  • B cells
  • Antigen presenting cells
  • Macrophages

Question 100

Question
The characteristics of passive immunity include
Answer
  • immediate relief
  • no immunologic memory
  • resistance for a short period only
  • all of these

Question 101

Question
Immunologic memory is provided by
Answer
  • B cells
  • T cells
  • Both a and b
  • Phagocytes

Question 102

Question
A method for cell sorting based on the surface antigens (markers) which react specifically with fluorescent-labelled antibodies is called
Answer
  • Flowcytometry
  • Immunofluorescent technique
  • Immunoelectrophoresis

Question 103

Question
A technique in which tissues and cells are examined by a fluorescent light microscope using fluorescent-labeled antibodies is called
Answer
  • Immunofluorescent technique
  • Flowcytometry
  • Immunoelectrophoresis

Question 104

Question
A technique for the identification of proteins in serum or other fluid by electrophoresis and subsequent immunodiffusion is called
Answer
  • Immunoelectrophoresis
  • Flowcytometry
  • Immunofluorescent technique

Question 105

Question
Classical pathway of complement system is activated by
Answer
  • antibody-antigen complexes
  • antigen
  • antigenic peptides
  • antigens bound to MH

Question 106

Question
Alternate pathway of complement system is activated by
Answer
  • antibody-antigen complexes
  • antigen
  • microorganisms or its toxins
  • antigens bound to MHC

Question 107

Question
Classical pathway of complement system is involved in
Answer
  • specific defence
  • adaptive immunity
  • both a and b
  • non-specific defence

Question 108

Question
Alternate pathway of complement system is involved in
Answer
  • non-specific defence
  • innate immunity
  • both a and b
  • adaptive immunity

Question 109

Question
Complement system
Answer
  • consists of 20 serum proteins
  • serum proteins acts as biological cascade
  • both a and b
  • are set of antibodies

Question 110

Question
Complement system is involved in
Answer
  • specific defence
  • non-specific defence
  • both a and b
  • none of these

Question 111

Question
Kupffer cells are macrophages found on
Answer
  • lung
  • bone
  • nephrons
  • liver

Question 112

Question
Antiviral glycoproteins released by living cells in response to viral attack and induce a viral resistant state to neighboring cells is called as
Answer
  • natural killer cells
  • complement system
  • phagocytes
  • interferons

Question 113

Question
Newborns get their antibodies from mothers milk. This is an example of
Answer
  • Naturally acquired active immunity
  • Artificially acquired active immunity
  • Naturally acquired passive immunity
  • Artificially acquired passive immunity

Question 114

Question
Which of the following is the site of T cell maturation?
Answer
  • Bone marrow
  • Thymus
  • Spleen
  • Appendix

Question 115

Question
Primary lymphoid organs include
Answer
  • Thymus and spleen
  • Thymus and bone marrow
  • Thymus, bone marrow and spleen
  • Thymus, bone marrow, spleen and lymph nodes

Question 116

Question
The major chemical messenger involved in hypersensitivity is
Answer
  • interferons
  • histamines
  • lymphokines
  • interleukines

Question 117

Question
HIV attacks:
Answer
  • macrophages
  • B cells
  • T cytotoxic cells
  • T helper cells

Question 118

Question
Regarding the inflammatory response:
Answer
  • Tissue swelling is the first stage of the inflammatory response.
  • Mast cells secrete chemotactic agents that attract lymphocytes
  • Macrophages secrete vasoactive materials during the inflammatory response
  • The inflammatory response can be triggered by antibody binding to the surface of micro-organisms.

Question 119

Question
Natural killer cells only destroy cells infected with a virus.
Answer
  • True
  • False

Question 120

Question
The antigens below are on your erythrocytes (red blood cells) which antibodies would you expect to find in the serum 1/ A- [blank_start]B[blank_end] 2/ B- [blank_start]A[blank_end] 3/ O- [blank_start]AB[blank_end]
Answer
  • B
  • A
  • AB
  • O
  • A
  • B
  • AB
  • O
  • AB
  • O
  • A
  • B

Question 121

Question
Fill in the Blanks (No - symbol needed) 1/ Precursor Chain + [blank_start]L fucose[blank_end]= H-Antigen 2/ H-Antigen + [blank_start]N acetylgalactosamine[blank_end]= A-Antigen 3/ H-Antigen + [blank_start]D Galactose[blank_end]= B-Antigen
Answer
  • L fucose
  • N acetylgalactosamine
  • D Galactose