Karteikarten
Digestive System

Karten in diesem Stapel (47)
- 1Organs of the Digestive System Two main groups
- Alimentary canal (also called the GI tract) continuous coiled hollow muscular tube
- Accessory digestive organs - 2Organs of the Alimentary Canal- Mouth
- Pharynx
- Esophagus
- Stomach
- Small intestine
- Large intestine
- Rectum
- Anus - 3Accessory Digestive Organs- Salivary glands
- Tongue
- Teeth
- Pancreas
- Liver
- Gall bladder - 4—


- 5Structure of Alimentary Canal- Mucosa - in contact with food substances Innermost layer
Moist membrane - mucus
- Submucosa - blood supply and nerves
-Muscularis externa
- Smooth muscle - circular and longitudinal Serosa – anchors organs - 6—


- 7Ingestion- Getting food into the mouth.
- This is an active, voluntary process - 8Propulsion- Moving foods from one region of the digestive system to another
- This includes:
Swallowing
Peristalsis
Segmentation - 9Propulsion- Peristalsis – alternating waves of contraction - oesophagus
- Segmentation – moving materials back and forth to aid in mixing - small intestine - 10Mechanical digestion - food breakdown- Mastication / Chewing = Grinding and mixing of food in the mouth by the teeth and tongue
- Churning of food in the stomach
- Segmentation (mixing) in the small intestine
- Prepares food for enzyme breakdown - 11Chemical Digestion – food breakdown- Enzymes break down food molecules into their building blocks (smallest units)
- Each major food group uses different enzymes
Carbohydrates are broken to simple sugars
Proteins are broken to amino acids
Fats are broken to fatty acids and glycerol - 12Absorption- End products of digestion are absorbed into the blood or lymph
- Active and passive transport
- Mostly in small intestine - 13Defecation- Elimination of indigestible substances as faces
- Large intestine - 14Mouth• Foodisingested
• Propulsionisinitiatedby swallowing
• Mechanicaldigestionbegins.
• Chemicalbreakdownofstarch
begins.
• The pharynx and esophagus serve as conduits to pass food from the mouth to the stomach - 15Saliva- Mixture of mucus and serous fluids
- Helps to form a food bolus
- Contains salivary amylase to begin starch digestion
- Dissolves food chemicals so they can be tasted by taste buds
 - 16Esophagus• Runs from the pharynx through the diaphragm to the stomach
• 25cm long
• Wall consists of the 4
basic layers.
• Peristalsis – aided by gravity - 17Stomach Anatomy- Food enters at the cardioesophageal sphincter
- 4 regions of the stomach
- Rugae – internal folds of the mucosa
- Food empties into the small intestine at the pyloric sphincter
- Volume 50 mls to 4 litres - 18—


- 19Stomach• Muscularis externa
• Has a third layer = oblique
• Allows the stomach to Propulsion in the Stomach churn, mix, and pummel food physically
• Breaks down food into smaller fragments
• CHYME - 20Propulsion in the Stomach- Food must first be well mixed
- Rippling peristalsis occurs in the lower stomach
- The pylorus lets out chyme into the small intestine (3 mls at a time)
- The stomach empties in four to six hours - 21Stomach mucosa• Mucosa is composed of:
– Goblet cells that produce a coat of alkaline mucus
–The mucous surface layer traps a bicarbonate-rich fluid beneath it
– To protect from self
– digesting
– Gastric pits - 22Gastric pits lead to gastric glands• Gastric glands have a variety of secretory cells:
- Mucous neck cells – secrete mucous
- Parietal cells – secrete HCl and intrinsic factor - Chief cells – produce pepsinogen
• Pepsinogen is activated to pepsin by:
- HCl in the stomach
- Pepsin itself via a positive feedback
mechanism - 23Stomach Functions- Acts as a storage tank for food
- Site of food breakdown (churning)
- Secretion of gastric juice
- Chemical breakdown of protein begins
- No absorption
- Delivers chyme (processed food) to the small intestine
- Secretes intrinsic factor required for absorption of vitamin B12 - 24Digestion and Absorption in the Stomach Protein digestion enzymes
Pepsin – an active protein digesting enzyme
The only absorption that occurs in the stomach is of alcohol and aspirin - 25Small Intestine
Subdivisions of the small intestine
Duodenum - 25 cms
Jejunum – 2.5 ms
Ileum – 3.6 ms
The bile duct and main pancreatic duct empty secretions into the small intestine at the duodenum - 26Anatomy of Small Intestine Folds called circular folds or plicae circulare
Designed for absorption and large folds designed to slow down passage of chyme
Villi - fingerlike structures formed by the mucosa
Give the small intestine more surface area - absorption - 27Villi of the Small Intestine Between villi are pits containing glands that secrete intestinial juices.
Villi, in turn, have microvilli which secrete enzymes (brush border enzymes) - 28Microvilli Of The Small Intestine Microvilli = Small projections of the plasma membrane of the absorptive cells
Brush border enzymes - 29Pancreas – pancreatic juice Produces a wide spectrum of digestive enzymes that break down all categories of food
Enzymes are secreted into the duodenum
Alkaline fluid (bicarbonate) introduced with
enzymes neutralizes stomach contents
Endocrine products of pancreas - control blood glucose levels
Insulin - blood glucose high (after meal).
Glucagon - blood glucose low (between meals) - 30Liver Largest gland in the body
Metabolic and regulatory roles
Digestive role to produce bile - 31Bile Produced by cells in the liver
Gallbladderstoresand concentrates bile from the liver
Bile is introduced into the duodenum in the presence of fatty food - emulsifies fat to aid enzymatic breakdown - 32Propulsion in the Small Intestine Peristalsis is the major means of moving food
3-6 hour journey through small intestine Segmentation movements
Mix chyme with digestive juices
Aid in propelling food - 33Chemical Digestion in the Small Intestine Most chemical digestion occurs in the small intestine
Source of enzymes that are mixed with chyme to give intestinal juice
Pancreas = pancreatic juice
Intestinal cells - brush border enzymes
Bile enters from the gall bladder - 34Chemical digestion - Carbohydrates

- 35Chemical digestion - Protein

- 36Chemical digestion - Fats

- 37Chemical digestionUnemulsified Fats (lipids)
• Bile enters small intestine from the gall bladder
• Bile emulsifies the fat this allows enzymes to start fat breakdown
• Pancreatic lipase from the pancreas enters the small intestine
• Pancreatic lipase aids in breaking down the fat. - 38Absorption of digested food components. A• Carbohydrates-finalbreakdownproducts
• Monosaccharides - glucose, galactose, fructose enter
the capillaries of the villi
• via co-transport with Na+, and facilitated diffusion - 39Absorption of digested food components. B• Protein-finalbreakdownproducts
• Amino acids enter the capillary of the villi
• Both monosaccharides and amino acids are transported to the liver by the hepatic portal vein - 40Absorption of digested food components• Fat - final breakdown products
• Fatty acids and glycerol are absorbed into the lacteal of the villi as a chylomicron
• Enters the lymphatic system
• Lymph is drained back into blood at the thoracic duct
• Fatty acids then enter the liver for distribution to other body areas. - 41Brushborder enzymes Found in the microvilli
Final breakdown to produce single units ready for absorption - 42Structures Involved in Absorption of Nutrients Absorptive cells
Blood capillaries
Lacteals (specialized lymphatic capillaries) - 43Large Intestine Larger in diameter, but shorter than the small intestine
Frames the internal abdomen
Subdivisions:
Cecum
Appendix
Colon
Rectum
Anal canal - 44ColonDistinct regions:
Ascending
Transverse
Descending
Sigmoid
Goblet cell – mucus
Longitudinal muscle – teniae coli
Haustra - 45Food Breakdown and Absorption in the Large Intestine No digestive enzymes are produced
Resident bacteria digest remaining nutrients
Produce some vitamin K and B
Release gases approx 500ml/day
Water and vitamins K and B are absorbed Remaining materials are eliminated = feces
Undigested food, mucus, bacteria, water - 46Propulsion in the Large Intestine Residue moves along slowly in 12 -24 hours
Haustral contractions
Mass movements
Slow, powerful movements
Occur three to four times per day
Presence of feces in the rectum causes a defecation reflex - 47Defecation reflex• Rectum is generally empty
• Mass movements force feces into rectum and
stretch the wall - signals the defecation reflex
• Internal sphincter relax (involuntary)
• External sphincter remains closed (voluntary)
• If convenient defecation can occur - voluntary relaxation of external sphincter
• If not convenient, defecation can be delayed temporarily
Informationen
- Beschreibung
- 5 HAP 1 Karteikarten am Digestive System, erstellt von Jonathan Cash am 21/10/2015.
- Erstellt von
- Jonathan Cash · Okt 2015
- Aktualisiert
- 4 Feb 2018
- Aufrufe
- 1
- Tags
- Bewertung