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Bacterial Cell Wall

Nicole Bolo Biology 123: Microbial Physiology Englisch 41 Karten

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  1. 1structure present in Archaea instead of peptidoglycanpseudomurein
  2. 2another term for peptidoglycanMurein
  3. 32 fxns of peptidoglycanmaintenance of the cell integrity, resistance from osmotic lysis
  4. 42 sugar backbones of peptidoglycanNAG (N-accetyl glucosamine) &
    NAM (N-acetylmuramic acid)
  5. 5tetra amino side chainsL-alanine, D-glutamic acid , DAP (Diaminophenelic acid) in G(-) or L-lysine in G(+), D-alanine
  6. 6bonds that connect the peptidoglycan monomers- Glyosidic bonds
  7. 7process which create the cross bridging between peptidesTranspeptidation
  8. 8Usable form of aaL-form
  9. 9advantage for having D-form aaprotection against digestion of proteases (not easily detected)
  10. 10peptide cross link in G-DAP - D-ala
  11. 11peptide cross link in G+L-lys to D-ala
  12. 12characteristic of G- cell walldense
  13. 13characteristic f G+cell wallthick peptidoglycan layer
  14. 14cause of thick peptidoglycan layerpeptide interbridge (made up of 5 glycine)
  15. 15Starting material in peptidoglycan synthesisfructose-6-phosphate
  16. 16To which molecule does NAG interact with to form NAM?Uridine Diphosphate
  17. 17How is NAG converted to NAM?Lactyl group is added to C-3 of UDP-NAG to form UDP-NAM
  18. 18T or F: tRNA & ribosomes are used in peptide addition in peptidoglycan synthesisFalse (NOT used)
  19. 19transport lipid which carries NAG-NAM-5AAundecaprenyl-monophosphate
  20. 202 processes occurring in the cell wall upon peptidoglycan synthesisTransglycosylation & Transpeptidation
  21. 21examples of beta-lactam antibioticspenicillin, cephalosporins
  22. 22mechanism of beta-lactam antibioticsthe absence of the peptide bridge due to the binding with transpeptidase enzyme
  23. 23example of Glycopeptide antibioticsvancomycin
  24. 24mechanism of glycopeptide antibioticsprevents the formation of peptide cross-links by bindingto the penta-peptide side chains
  25. 25mechanism of bacitracinPrevents the dephosphorylation of bactoprenol resulting to the inhibition of monomer transport
  26. 263 types of peptidoglycan hydrolases1. Glycan-strand hydrolyzing enzyme,
    2. Endopeptidase hydrolyzing enzyme,
    3. N-acetylmuramoyl-L-amanine amidase enzyme
  27. 27mechanism of Glycan-strand hydrolyzing enzyme- Hydrolyzes the B-1,4 glycosidic bonds bet NAM& NAG
  28. 28mechanism of Endopeptidase hydrolyzing enzymeBreaks the cross link between the peptides
  29. 29mechanism of N-acetylmuramoyl-L-amanine amidase enzymebreaks the connection bet. the sugar backbone & aa side chain
  30. 30describe: G+ cell wall- Thick peptidoglycan
    - Thin periplasmic space
  31. 31unique structures in G+ cell wallsteichoic acids & lipoteichoic acids
  32. 32fxn of teichoic acidsvirulence factor required for host colonization
  33. 33Teichoic acids which extend until the cell membranelipoteichoic acids
  34. 34fxn of Lipoteichoic acidsstructural support
  35. 35components of Lipoteichoic acidsglycerol or ribitol
  36. 36Most abundant protein in OMBraun’s lipoprotein
  37. 373 parts of lipopolysaccharideLipid A, core polysaccharide, O side chain
  38. 38fxn of O side chainbacteria become less susceptible to detection of antibodies
  39. 39special structures in outer membraneporins
  40. 404 reagents in Gram stainingCrystal violet, iodine, ethanol, safranin
  41. 41differential sep in G stainingethanol decolorization

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Beschreibung
Biology 123: Microbial Physiology Karteikarten am Bacterial Cell Wall , erstellt von Nicole Bolo am 09/09/2014.
Erstellt von
Nicole Bolo · Sep 2014
Aktualisiert
19 Feb 2016
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