Emulsions

Emulsions

1. Formulation Factors

   • Excipients
     • Emulsifying agents
       • Natural
         • Animal origin
           • Casein
         • Plant origin
           • Acacia
       • Finely Divided solids
         • Aluminum Hydroxide
       • Surfactants
         • Tween / Span
         • Sodium Stearate
         • Cetrimide
         • Amphoteric
       • Auxiliary emulsifiers
         • Stearic acid
   • Route of Administration
     • Topical Route
       • Water in Oil (W/O)
     • Oral / Parental Route
       • Oil in Water (O/W)
   • Technique
     • Dry gum
     • Wet gum
     • In situ
     • Bottle
   • Absorption

2. Stability Factors

   • Reversible
     • Flocculation
     • Creaming
     • Phase Inversion
   • Irreversible
     • Coalescence
     • Phase Separation / Cracking / Breaking

3. Pre-formulation factors

   • Solubility
     • Dilution
     • Conductivity
     • Dye solubility
   • Particle Size
     • Coarse dispersion
       • >0.1 um
     • Molecular dispersion
       • less than 1.0 um
     • Colloidal dispersion
       • 1.0 nm - 1.0 mm
   • pH
     • Acid
     • Base

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