DIGESTIVE SYSTEM

DIGESTIVE SYSTEM

1. GALT

   • GUT ASSOCIATED LYMPHOID TISSUE
     • TOASL
       • TONSILS
         • OESOPHAGUS
           • APPENDIX
             • SMALL INTESTINE
               • LARGE INTESTINE

2. PEYER'S PATCHES

   • AGGREGATIONS OF GALT
     • FOUND LAMIA PROPIA AND SUBMUSCOA OF ILEUM
       • EGG SHAPED
         • MONITOR BACTERIA - PREVENT PATHOLOGICAL BACTERIA
           • LOTS OF WBCS

3. PERITONEUM

   • LARGEST SEROUS MEMBRANE IN THE BODY
     • LINES THE ABDOMINAL CAVITY
       • 2 LAYERS
         • PARIETAL - COVERS WALLS OF ABDOMEN AND PELVIC CAVITY
         • VISCERAL - COVERS THE ORGANS
   • PERITONITIS - acute inflammation of the peritoneum
   • GREATER OMENTUM - APRON DRAPES OVER INTESTINES - LARGEST FOLD IN PERITONEUM

4. SALIVARY GLANDS

   • PARATOID
   • SUBLINGUAL
   • SUBMANDIBULAR
   • CONSITITUENTS OF SALIVA - MIMEWB
     • MINERAL SALTS
       • IMMUNOGLOBULINS
         • MUCOUS
           • ENZYMES
             • amylase
             • lysozyme
             • WATER
               • BLOOD CLOTTING FACTORS
               • 99.5%
   • FUNCTIONS
     • digestion, lubrication, defence, taste, waste removal

5. MYENTERIC PLEXUS

   • BETWEEN CIRCULAR AND LONGITUNDIAL MIUSCLES OF THE MUSCULARIS
     • MOTILITY

6. SUBMUCOSAL PLEXUS

   • BETWEEN MUSCULAR AND SUBMUCOSAL LAYER
     • GLANDULAR SECRETIONS

7. ENTERIC NERVOUS SYSTEM

8. DOW JONES INDEX

9. LIVER

   • HEPATIC ARTERY BRINGS OXYGENATED BLOOD FROMT THE HEART
   • PORTAL VEIN BRINGS NUTRIENT AND TOXIN RICH BLOOD FROM THE GIT TO BE METABOLSED AND FILTERED
   • KUPFFER CELLS - PHAGOCYTIC CELLS DEAL WITH TOXINS
   • PORTAL VEIN AND HEPATIC ARTERY MIX IN THE SINUSOIDS
   • FUNCTIONS - BCDSM
     • BILE PRODUCTION
       • CLEANSING
         • DETOXIFICATION
           • STORAGE
             • METABOLISM
   • DETOXIFICATION
     • PHASE 1
       • CYTOCHROME P450 ENZYMES
         • OXIDISATION, REDUCTION, HYDROLISIS
           • MAKES TOXIN WATER SOLUBLE SO THAT IT CAN BE EXCRETED BY THE KIDNEYS
             • MAKES TOXIN INTO LESS HARMFUL ONE TO BE METABOLISED IN PHASE 2
     • PHASE 2
       • CONJUGATION PATHWAY
         • ADDS SOMETHING TO CHEMICAL TO MAKE IT LESS HARMFUL, NEUTRALISE IT

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