Homeostasis

Homeostasis

1. Interstitial Fluid

   • 15% of total body weight

2. Blood Flow

   • Arteries
     • high [O2]  low [CO2]
     • Aorta
       • largest artery
     • Coronary Arteries
       • deliver blood to myocardium
     • Descending Aorta
     • Hepatic Artery
       • goes to the liver
       • Liver
         • Hepatocytes
         • Glucose to Glucagon
         • Bile Production
         • Stores Fe2+
         • Detoxifies Alcohol & Drugs
         • Hepatic Duct
           • Drains Bile into Gall Bladder
             • Cystic Duct
               • Drains Bile From Gall Bladder
               • Common Bile Duct
           • Common Bile Duct
     • Pancreatic Artery
       • goes to pancreas "mixed gland"
       • Pancreas
         • Endocrine
           • Digestive Enzymes & Sodium Bicarbonate
             • Pancreatic Duct to Small Intestine
         • Exocrine
           • Glucagon & Insulin
             • Hepatic Portal Vein
     • Arteries to GI Tract
       • digestion - breakdown of food absorption - movement of nutrients into bloodstream
     • Splenic Artery
       • goes to spleen
       • Spleen
         • Macrophages & Lymphocytes
         • Recycles Old RBCs
           • Hemoglobin
             • Heme
               • red pigment
               • Fe2+
               • Bilirubin
                 • Splenic Vein
                   • Hepatic Portal Vein
             • Globin
               • protein
               • Amino Acids
                 • Splenic Vein
                   • Hepatic Portal Vein
     • Renal Arteries
       • goes to kidneys
       • Kidneys
         • Urine Formation
           • removal of waste products H2O & electrolyte balance
         • BP Regulation
           • adjust volume of H2O & Na+ secretion of renin
         • Production of Erythropoietin
     • Arterial supply to bones
       • store Ca2+ produce blood cells
     • Arterial supply to muscles
       • metabolism waste: CO2, heat, lactic acid
     • Arterial supply to reproductive organs
       • Blood may contain FSH, LH
   • Veins
     • low [O2] high [CO2]
     • Superior & Inferior Vena Cavae
     • Coronary Veins
       • drains blood from myocardium
     • Hepatic Portal Vein
       • drains blood from pancreas, spleen, & digestive organs
       • Hepatic Vein
         • blood drained from liver is clean and nutrient rich
     • Venous drainage from bones
     • Venous drainage from reproductive organs
       • Blood may contain estrogen, progesterone, testosterone
   • Capillaries
     • site of exchange
   • Sinusoids
     • leaky blood capillaries
     • Macrophages
       • Kupffer Cells

3. Lymphatic Circulation

   • absorb excess fluid
     • recycle into large veins
   • Blood supply
     • Defense
     • Phagocytosis
     • Production of Antibodies
   • Lymph Nodes
     • Filters/Destroys Pathogens

4. Pulmonary Circulation

   • Pulmonary Arteries
     • low [O2] high [CO2]
   • Pulmonary Veins
     • high [O2] low [CO2]
   • Lungs

5. Systemic Circulation (general)

   • Carotid Arteries
     • to brain
   • Baroreceptors
     • changes in BP
     • Carotid Sinuses
   • Chemoreceptors
     • changes in blood pH
     • Carotid Bodies

6. Hypothalamus

   • temp balance; H2O balance; autonomics produces hormones
   • ADH, Oxytocin, releasing/inhibiting horomones
   • Hypothalamic Hypophyseal Portal System
     • capillary - vein - capillary

7. Adenohypophysis (Anterior Pituitary)

   • FSH, LH, TSH, GH, Prolactin, ACTH

8. Endocrine Organs

   • hormones