Zusammenfassung der Ressource
Biology Unit 2
- Microorganisms and disease
- Symptoms can be
caused by cell
damage or by toxins
- Malaria symptoms caused
by cell damage
- E-coli releases toxins
- Microorganisms reproduce
quickly inside the body
- Bacteria make
copies of themselves
- Viruses need other
cells to reproduce
- The immune system
- Fights of invading
microbes
- Responses always
involve white blood cells
- White blood cells can
engulf and digest the
microorganisms
- Antibodies recognise
foreign microorganisms
- Sends out correct antibody to
fight the antigen on the microbe
- Antibodies are proteins
specific to a particular antigen
- Vaccination
- Use a safe version of a
dangerous microorganism
- First infection- takes a while
for white blood cells to respond
- Immunisation- infecting with dead
or inactive microorganisms
- Memory cells
remember antigens
- If live microorganisms appear AGAIN the body can make
antibodies more quickly to kill the microorganism more quickly
- Prevents epidemics
- Have different effects
on different people
- Antimicrobials
- Can inhibit or kill bacteria,
fungi and viruses
- Antibiotics are one type
- Clear up infections
- Microorganisms can evolve
and become resistant
- Always finish antibiotic course
- More courses of antibiotic- leaves
only the resistant microbes
- Drug Trials
- Tested in a
lab first
- developed
using lab grown
human cells
- Can't predict how
it will effect a living
human
- Test on humans = clinical trial
- Blind trial- patients
don't know if they have
the placebo or drug
- First on healthy volunteers
- Then ill people
- Placebo's are used
- Not ethical on
very ill patients
- Double blind trial- even
scientist doesn't know what
they are giving the patient
- Open label trials- all parties are
aware of what is being used
- The circulatory system
- Arteries- blood away
from the heart- thick walls
for the high pressure
- Veins- back to heart-
thin walls big lumen
- Capillaries- one cell thick
- heart rate and
blood pressure
- Pulse rate used
to measure your
heart rate
- Heart rate in BPM
- Blood pressure- the pressure
of blood against artery wall
- Two values
- HIgher= pressure
when heart contracts
- Lower= pressure
when heart relaxes
- Average healthy lower- 60-100 BPM
- High blood pressure
increases risk of heart
disease
- Build up of fatty deposits
increase blood pressure
- if deposit breaks through
inner lining of the artery a
blood clot could form around it
- if a coronary artery
becomes blocked it cuts off
the blood and oxygen supply
to part of the heart and this
part dies.
- Heart disease
- Poor diet
- Cholesterol makes
most of fatty deposits
- High blood cholesterol is linked to
eating foods with high saturated
fats e.g. fatty meats and cheese
- Salt increases risk- it
increases blood pressure
- Smoking
- carbon monoxide and nicotine increase risk
- CO reduces amount of oxygen in the blood
- If the heart doesn't
get enough oxygen-
heart attack
- Stress
- + BP = +risk of
heart disease
- Illegal drugs
- + heart rate =+ risk
of heart disease
- Same as excessive alcohol
- Homeostasis
- Maintaining a constant
internal environment
- Controlling water
content
- Inputs- water can be
gained from drink,
food and respiration
- Outputs-
sweating,
breathing,
faeces and
urine
- Kidneys help balance
substances in the body
- Filter small molecules
from the blood
- Reabsorb- all the sugar and as much
salt and water as the body requires
- Urine isn't always the same
- External temperature
- Effects how much you sweat-
more sweat= water loss so
kidneys will reabsorb more
water back into the blood
- Small amount of
concentrated urine
- Exercise- makes you
hotter- sweat to cool down
- Intake of fluids and salts- eating too much salt/not
enough water=concentrated small amount of urine