Quiz
PHSI3011 10-1 Complex Systemic Homeoastasis
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1Glucose is a 6-Carbon ring that’s metabolisable as a “D-isomer”. It’s C6-H[x]-O[y]?
- AX = 12; Y = 6
- BX = 6; Y = 6
- CX = 6; Y = 12
- DX = 12; Y = 12
2Glucose is a:
- AMonosaccharide
- BPolysaccharide
- CMonoglyceride
- DPolyglyceride
3Glucose is consumed as starch and glycogen and broken down to glucose by [blank_start]__________[blank_end] [blank_start]__________[blank_end] [blank_start]__________[blank_end] for transport across the enterocytes.
- AExocrine
- BEndocrine
- CAutocrine
- DParacrine
- EPancreatic
- FHepatic
- GLeukocytic
- HLymphatic
- IGlycosidases
- JGlycocytes
- KGlycosides
- LGlycogenases
4How much of the postprandial glucose disposal is accounted for by skeletal muscle glucose uptake? (in humans)
- A~70-80%
- B~20-30%
- C~50-70%
- D~30-50%
- E~80-90%
- F~10-20%
5Triglycerides (/“Triacylglycerols”) are complex lipids that are 3 Fatty Acids attached to a [blank_start]_______[blank_end] backbone.
- A3 Carbon Glycerol
- B3 Carbon Glycogen
- C5 Carbon Glycerol
- D5 Carbon Glycogen
6Free Fatty Acids (“NEFA”: Non-Esterified Fatty Acids) are released from [blank_start]__________[blank_end] and circulate bound to [blank_start]__________[blank_end].
- AAdipocytes
- BAlbumin
7Triglycerides (/TriAcylGlycerols/TAGs) circulate in lipoproteins secreted from the Liver or Gut. Which type of lipoprotein is secreted from each of the two?
Liver: [blank_start]__________[blank_end]
Gut: [blank_start]__________[blank_end]- AVLDL
- BLDL
- CHDL
- DChylomicron
- EChylomicron
- FVLDL
- GLDL
- HHDL
8ADIPOSE-DERIVED Fatty Acids are taken up by which tissues?
- ALiver
- BGut
- CMuscle
- DLiver and Gut
- ELiver and Muscle
- FGut and Muscle
- GAll of the above
- HNone of the above
- IALL tissues
9Once dietary TriAcylGlycerols have been hydrolysed and transported across the enterocytes, they’re then esterified back into TriAcylGlycerols and packaged into:
- AChylomicrons
- BVLDLs
- CLDLs
- DHDLs
10Once adipose-derived Fatty Acids are taken up by the liver, they’re esterified into TriAcylGlycerols and packaged into:
- AChylomicrons
- BVLDLs
- CLDLs
- DHDLs
11Chylomicron-TG is metabolised at the tissue level by [blank_start]__________[blank_end], which hydrolyses CM-TG to release FA for tissue uptake.
- ALipoProtein Lipase (LPL)
- BLow-Density Lipoproteins (LDLs)
- CHigh-Density Lipoproteins (HDLs)
- DVery Low-Density Lipoproteins (VLDLs)
12After hydrolysis of the Chylomicron-TG, the particle becomes smaller, forming CM-remnant.
This remnant particle is taken up by the [blank_start]__________[blank_end] and the TG remaining in the particle can be repackaged into a [blank_start]__________[blank_end], thereby recycling the dietary FA.- ALiver
- BGut
- CMuscle
- DVLDL
- EHDL
- FLDL
- GLPL
- HVLPL
- IChylomicron
13Label all those bits.
- AChylomicron
- BLDL
- CVLDL
- DLPL
- EHDL
- FVLPL
- GLPL
- HVLPL
- ILDL
- JVLDL
- KHDL
- LChylomicron
- MChylomicron remnant
- NVLDL remnant
- OLDL remnant
- PHDL remnant
- QVLPL remnant
- RLPL remnant
- SVLDL
- TLDL
- ULPL
- VVLPL
- WHDL
- XChylomicron
- YLiver
- ZAdipose
- AAMuscle
- ABAdipose
- ACLiver
- ADMuscle
- AEMuscle
- AFAdipose
- AGLiver
14Which two mostly carry TAGs (/TAs/TriAcylGlycerols/TriGlycerides)?
- AChylomicron
- BVLDL
- CLDL
- DHDL
15Which two carry mostly* Cholesterol?
(not actually mostly, but more than TAGs)- ALDL
- BHDL
- CVLDL
- DChylomicron
16Glucose uptake is limited by GLUT levels at the plasma membrane… …but can be overcome by an increase in levels of what?
- AHK2
- BHK1
- CSA1
- DSA2
17The rate of fatty acid oxidation is controlled by the rate of FA entry into the mitochondria – this step is catalysed by what? (the activity of which is regulated by malonyl-CoA through ALLOSTERIC REGULATION)
- ACPT1
- BCPT2
- CHK1
- DHK2
18The modification of proteins is a highly conserved process that regulates protein/enzyme activity. A diverse range of PTMs include:
[blank_start]__________[blank_end]: Addition of a phosphate (from ATP or similar triphosphates)
[blank_start]__________[blank_end]: Addition of acetate from acetyl-CoA
[blank_start]__________[blank_end]: Addition of a glucose molecule
[blank_start]__________[blank_end]: Include myristolyation (C14), palmitolyation (C16)- APhosphorylation
- BAcetylation
- CGlycosylation
- DLipidation
19Can Phosphorylation activate or inactivate an enzyme?
- AActivate
- BInactivate
- CNeither
- DEither
20True or false: The synthesis of new protein is another point of regulation. An example of this is Gluconeogenesis.
- ARichtig
- BFalsch
Informationen
- Beschreibung
- PHSI3011 10-1 Complex Systemic Homeoastasis
- Autor
- Gelöschter Nutzer
- Sprache
- English
- Aufrufe
- 30
- Verlauf
- Erstellt am 1 Nov 2017 · aktualisiert am 10 Nov 2017
- Schlagwörter
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