297549
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor mehr als 10 Jahre
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Frage 1
Frage
Which form of Glycogen Phosphorylase is relatively inactive?
Antworten
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Phosphorylase A
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Phosphorylase B
Frage 2
Frage
In phosphorylase B, where is the N terminus?
Antworten
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Floating free in the cytoplasm
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Attached to the protein body
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Unattached from protein
Frage 3
Frage
Which of the forms of glyocgen phosphorylase is most effected by cellular AMP/ATP levels?
Antworten
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Phosphorylase A
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Phosphorylase B
Frage 4
Frage
Which of the following phosphorylates Glycogen Phosphorylase?
Antworten
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Phosphorylase B Kinase
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Phosphorylase A Kinase
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Phosphorylase Kinase
Frage 5
Frage
What protein causes the dephosphorylation of phosphorylase?
Antworten
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Protein phosphatase
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Protein phosphorylase
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Prokein Kinase P
Frage 6
Frage
What is needed for the reaction of Phosphorylase B --> A to reverse itself?
Antworten
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Water (and a lack of inhibiting AMP)
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Water (and a lack of inhibiting ATP)
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Water (and a lack of inhibiting GMP)
Frage 7
Frage
What is different about Phosphorylase A to B?
Antworten
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Ser14 has been phosphorylated
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Tyr14 has been phosphorylated
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Thr14 has been phosphorylated
Frage 8
Frage
What difference does phosphorylating Glycogen phosphorylase make?
Antworten
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Makes the relaxed form much more likely
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Makes the taut form much more likely
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Deactivates it entirely
Frage 9
Frage
How does phosphorylase B Kinase connect Glycogen Phosphorylase levels to the level of stimulation?
Antworten
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It is activated by Ca2+- when the muscle is stimulated, glucose is needed and so glycogen is broken down
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It is deactivated by Ca2+- when the muscle is stimulated, glucose is not needed and so glycogen isn't broken down
Frage 10
Frage
What part of Phosphorylase B Kinase binds to Calcium?
Antworten
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Calmodulin
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Calsequestrin
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Troponin C
Frage 11
Frage
Which parts of phosphorylase B kinase are regulatory?
Antworten
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Alpha and beta
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Alpha and gamma
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Gamma and beta
Frage 12
Frage
Which part of phosphorylase B kinase is catalytic?
Antworten
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Gamma
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Delta
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Beta
Frage 13
Frage
In phosphorylase B kinase's Ca2+ binding sites, what are the affinities?
Antworten
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2 high 2 low
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4 high
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4 low
Frage 14
Frage
What protein causes the phosphorylation of Phosphorylase B Kinase?
Antworten
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cAMP dependent Protein Kinase
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Adenylate Cyclase
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Glycogen Phosphorylase
Frage 15
Frage
What is another name of cAMP dependent protein kinase?
Antworten
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Protein Kinase A
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Protein Kinase B
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Protein Kinase C
Frage 16
Frage
What is the role of inhibitor one?
Antworten
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To bind to protein phosphatase, activating it
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To bind to protein phosphatase, inhibiting it
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To bind to protein kinase A, activating it
Frage 17
Frage
What is contained in the N terminus domain of Glycogen Phosphorylase?
Antworten
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The catalytic site
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The allosteric effector site
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The regulatory subunit
Frage 18
Frage
How does glycogen get from it's binding domain to the catalytic site?
Antworten
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A hydrophobic tunnel
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A hydrophillic tunnel
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A lipophobic tunnel
Frage 19
Frage
Why is glycogen phosphorylase's site in a deep groove?
Antworten
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To prevent AMP from entering
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To prevent ATP from entering
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To prevent water from entering
Frage 20
Frage
What happens if water enters the active site?
Antworten
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Nothing
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The enzyme is deactivated
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Hydrolysis occurs instead of phosphorolysis
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