Alternative Oxidase

Beschreibung

Structural Basis for Biological Function (Membrane Proteins) Quiz am Alternative Oxidase, erstellt von gina_evans0312 am 18/12/2013.
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312 vor mehr als 10 Jahre
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Zusammenfassung der Ressource

Frage 1

Frage
Why is human african tropanomosis so common?
Antworten
  • Most drugs are outdated
  • Most drugs have severe side effects
  • Most drugs are incredibly expensive
  • Most drugs cannot be used on the immunocompromised

Frage 2

Frage
The cause of Human African Tropanomosis is a virus known as Tropanosome
Antworten
  • True
  • False

Frage 3

Frage
Tropanosomes contain 1 mitochondria that depends on what for energy?
Antworten
  • Glycerol-3-Dehydrogenase
  • Succinate Dehydrogenase
  • NADH Dehydrogenase
  • Malate Dehydrogenase

Frage 4

Frage
The enzyme that tropanosomes rely on allows glycolysis to continue indefinitely
Antworten
  • True
  • False

Frage 5

Frage
What other components make up the tropanonsome's mitochondria?
Antworten
  • Alternative Oxidase
  • Quinol
  • Cytochrome C
  • Cytochrome BC1 complex

Frage 6

Frage
How does Alternative Oxidase get its energy source?
Antworten
  • Glucose in the blood plasma
  • Glucose in the infected red blood cell
  • Glucose from other blood proteins

Frage 7

Frage
Cryptosporidium Parvum can only become fatal to the immunocompromised
Antworten
  • True
  • False

Frage 8

Frage
Name the following
Antworten
  • Cryptosporidium parvum cysts
  • Cryptosporidium parvum oocysts
  • Cryptosporidium parvum oocytes

Frage 9

Frage
Which of the following are characteristic of Alternative Oxidase?
Antworten
  • Membrane bound
  • Cytoplasmic
  • Reduces O2 to H2O
  • Reduces O2 to H2O2
  • No absorption about 340nm

Frage 10

Frage
Alt. Ox. is a 34kDa monomer
Antworten
  • True
  • False

Frage 11

Frage
Why does Alt. Ox. not absorb above 340nm?
Antworten
  • It contains no Cyt's or Fe-S
  • It contains no chromosomes
  • It contains no Cty's or Flavins

Frage 12

Frage
To activate, Alt. Ox must form a dimer
Antworten
  • True
  • False

Frage 13

Frage
What is particular about Rubreythrin?
Antworten
  • It is the olden protein yet sequenced - 4 billion years old
  • It's the smallest protein yet sequenced - just 40 aa long
  • It's the largest protein yet sequenced - 400,000 kDa

Frage 14

Frage
Only 6 aa in Alt. Ox have been conserved, relating it to other di-iron proteins
Antworten
  • True
  • False

Frage 15

Frage
The conserved sequence of Alt. Ox. codes for amino acids holding what?
Antworten
  • Iron
  • Magnesium
  • Copper
  • Sodium

Frage 16

Frage
Which of the following list characteristics of Alt. Oxidase?
Antworten
  • Sits horizontally in the membrane
  • Sits vertically in the membrane
  • Made of 2 chains, almost entirely of alpha helices
  • Made of 3 chains, almost entirely of alpha helices
  • Made of 2 chains, almost entirely of beta sheets

Frage 17

Frage
2 Alpha helices dock Alt. Ox in the membrane
Antworten
  • True
  • False

Frage 18

Frage
How does the substrate get to Alt. Ox's active site?
Antworten
  • Through a hydrophobic cavity
  • It is 'caught' by alpha helices extending into the cytoplasm
  • It uses membrane phospholipids which move through it

Frage 19

Frage
The following shows the core of Alt. Oxidase- what's contained in it?
Antworten
  • 2 Fe atoms
  • 2 Cu atoms
  • Linked by hydroxyl groups
  • Linked by amide groups
  • From 4 leucine residues
  • From 4 glutamine residues
  • And 2 Histadine &1 Tyrosine residues

Frage 20

Frage
The Histadine/Tyrosine residues can be used to inhibit Alt. Ox
Antworten
  • True
  • False

Frage 21

Frage
To travel through the channel and reach the active site, inhibitors must be...
Antworten
  • Hydrophobic
  • Hydrophillic

Frage 22

Frage
Different co-ordinations of the aa in the Alt. Ox core can alter the function of it
Antworten
  • True
  • False

Frage 23

Frage
Alt. Ox. is a terminal respiratory chain oxidase
Antworten
  • True
  • False

Frage 24

Frage
Where is Alt. Ox found, in infected humans?
Antworten
  • Between Complexes 1 & 2
  • Between complexes 2 & 3
  • Between complexes 3 & 4

Frage 25

Frage
Alternative Ox is used as a stress protein in pathogens, and an oxygen scavenger in plants
Antworten
  • True
  • False

Frage 26

Frage
Which of the following use Alt. Ox?
Antworten
  • American/Asian Skunk Cabbage
  • Dead Horse Arum
  • Sacred Lotus
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