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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor mehr als 10 Jahre
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Frage 1
Frage
What is the main role of cytochrome aa3?
Antworten
-
Takes e- from ubiquinol and reduces oxygen to water
-
Takes e- from ubiquinol and reduces oxygen to peroxide
-
Takes e- from cytochrome c and reduces oxygen to peroxide
-
Takes e- from cytochrome c and reduces oxygen to water
Frage 2
Frage
Complex IV contains how many subunits?
Antworten
-
12
-
13
-
14
-
15
Frage 3
Frage
Complex IV doesn't transfer protons across the inner mitochondrial membrane
Antworten
- True
- False
Frage 4
Frage
Which ions does it contain, and how many of each?
Antworten
-
2 Fe (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Cu centre)
-
2 Cu (in haeme groups) and 3 Fe (2 as a Fe-Fe binuclear centre, 1 as a binuclear Fe-Cu centre)
-
2 Mg (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Mg centre)
Frage 5
Frage
Cytochrome aa3 complex consists almost entirely of alpha helices
Antworten
- True
- False
Frage 6
Frage
Put the following in order
A- Cyt c
B- CuA centre
C- Cyt a
D- Cyt a3-CuB centre
E - Water
•Transfer from cyt a3-CuB centre to oxygen
Antworten
-
A-B-C-D-E
-
A-C-D-B-E
-
A-C-B-D-E
Frage 7
Frage
How many protons are pumped by complex 4, and how many are used to make water (per Oxygen molecule)?
Antworten
-
4 & 4
-
4 & 2
-
2 & 4
Frage 8
Frage
Which conformation of Complex IV has the low affinity for protons?
Antworten
-
Conf. A
-
Conf. B
-
Conf. C
Frage 9
Frage
Protons bind to Complex IV during Conformation B
Antworten
- True
- False
Frage 10
Frage
What happens during conformation B that lowers the Complex IV's affinity for protons?
Antworten
-
Energy is put in
-
Energy is lost
-
The protein has an Fe group added
Frage 11
Antworten
-
Okay?
-
Done
Frage 12
Frage
ATP synthase is found on the inner mitochondrial membrane
Antworten
- True
- False
Frage 13
Frage
ATP synthase is divided into two sections, F1 & F0
Which is peripheral and which is integral?
Antworten
-
F1 is peripheral F0 is integral
-
F0 is peripheral F1 is integral
Frage 14
Frage
Name the function of ATP synthase
Antworten
-
ATP synthesis
-
ATP hydrolysis
-
ATP translocation
-
Proton translocation
Frage 15
Frage
If ATP is high, and the proton gradient is low, what will Complex V do instead?
Antworten
-
Hydrolyse ATP
-
Synthesise GTP
-
Break itself down
Frage 16
Frage
Protons flow through F1 to power the ATP synthesis in F0
Antworten
- True
- False
Frage 17
Frage
Name the subunits of F1
Antworten
-
Alpha-Epsilon
-
A-E
-
1-5
Frage 18
Frage
Which of the following subunit(s) are the largest in F1?
Antworten
-
Alpha & Beta
-
Gamma & Delta
-
Beta and Gamma
-
Alpha and Epsilon
Frage 19
Frage
What is the role of the delta subunit in F1?
Antworten
-
Stabiliser for the F1 head
-
ATP synthesis
-
Connets F1 too F0
Frage 20
Frage
The epsilon subunit of F0 connects the gamma to the C subunit
Antworten
- True
- False
Frage 21
Frage
F0 contains how many subunits?
Antworten
-
2- A & B
-
3- A, B & C
-
2- Alpha & Beta
Frage 22
Frage
The F1 subunit is...
Antworten
-
8nm long
-
18nm long
-
12nm long
-
90nm wide
-
19nm wide
-
9nm wide
Frage 23
Frage
The Y subunit of F1 is made of 2 beta sheets that have been bent, but are bound at the base
Antworten
- True
- False
Frage 24
Frage
When the gamma subunit is in contact with a beta subunit, the ATP catalysis site is in it's _ formation
Antworten
-
Open
-
Loose
-
Tight
Frage 25
Frage
A subunit contains ADP + Pi- what conformation is it in?
Antworten
-
Loose
-
Tight
-
Open
Frage 26
Frage
Whilst the subunit is replacing ATP with ADP + Pi, the gamma subunit remains in plance
Antworten
- True
- False
Frage 27
Frage
What order do the three conformations work in?
Assume you start with the Loose formation
Antworten
-
Loose-Tight-Open
-
Loose-Open-Tight
Frage 28
Frage
State the characteristics of the C subunit of F0
Antworten
-
Small
-
Large
-
Hydrophobic
-
Hydrophilic
-
Integral
-
Peripheral
Frage 29
Frage
How many monomers make up the C subunit?
Antworten
-
8-12
-
8-10
-
4-10
Frage 30
Frage
The C subunit contains 3 rings of monomer
Antworten
- True
- False
Frage 31
Frage
Why is there a variance across species of the number of monomers in the C subunit?
Antworten
-
The more complex an organism, the more efficient the subunit
-
The more complex an organism, the less efficient the subunit
-
The larger the organism, the more subunits are required
-
Mammals have 8, birds have 12, all lesser animals and prokaryotes have 14 or more
Frage 32
Frage
More subunits require more protons to move them, so more subunits is less efficient
Antworten
- True
- False
Frage 33
Frage
How is the A subunit described?
Antworten
-
A proton half channel
-
A proton channel
-
A proton quarter channel
Frage 34
Frage
Protons passing through the A subunit...
Antworten
-
Use it to enter the C subunit and exit to the cytoplasm
-
Use it to exit into C subunit and enter from the cytoplasm
Frage 35
Frage
Each subunit can hold 2 protons
Antworten
- True
- False
Frage 36
Frage
The momevent of the protons around the C subunit powers what?
Antworten
-
The movement of the gamma subunit
-
The conformational changes of the beta subunits
-
The attachment of the alpha subunits
-
The rotation of the delta subunit
Frage 37
Frage
The rotation of the F1 has been proved by attaching a microtubule filament to the F1 head and examining it under the microscope
Antworten
- True
- False
Frage 38
Frage
Only the gamma subunit of the F1 complex rotates
Antworten
- True
- False
Frage 39
Frage
How is the Alpha/Beta spheroid of F1 held in place?
Antworten
-
B1 subunit
-
B2 subunit
-
Epsilon subunit
-
Delta subunit
Frage 40
Frage
For every _degree rotation, 1 molecule of ATP is produced
Antworten
-
90
-
120
-
180
-
360
Frage 41
Frage
The mechanism of the gamma subunit causes an affinity change for ATP/ADP + Pi, driving the cycle
Antworten
- True
- False
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