601950
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor etwa 10 Jahre
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Frage 1
Frage
Pre-Proinsulin contains an R.E.R signal that moves it to the golgi
Antworten
- True
- False
Frage 2
Frage
What is the role of the C-peptide part of the insulin chain
Antworten
-
Formation of disulphide bonds between the alpha and beta chains
-
Formation of Fe-S bonds between the alpha and beta chains
-
Formation of peptide bonds between the alpha and beta chains
Frage 3
Frage
Pro-insulin is made of the alpha & beta chains and the c peptide
Antworten
- True
- False
Frage 4
Frage
Which of the following cleave the c-peptide from the proinsulin?
Antworten
-
Endopeptidase
-
Enteropeptidase
-
Carboxypeptidase
Frage 5
Frage
What form does newly made insulin take?
Antworten
-
Granules
-
Crystals
-
Rods
Frage 6
Frage
The cleaved C-peptide is released along with the insulin
Antworten
- True
- False
Frage 7
Frage
Why do Mannoheptulases inhibit insulin release?
Antworten
-
The insulin secretion system relies on the phosphorylation of glucose, which MHLs inhibit
-
MHLs block excretory channels
-
MHLs prevent the movement of insulin to the RER
Frage 8
Frage
Optimum insulin secretion occurs at 8mM
Antworten
- True
- False
Frage 9
Frage
Why is optimal secretion of insulin at 8mM
Antworten
-
GLUT 2 & glucokinase have Kms of 8
-
Not gonna put anything else
-
Because reasons
Frage 10
Frage
Insulin secretion relies on ATP dependent K+ channels
Antworten
- True
- False
Frage 11
Frage
K+ buildup causes Ca2+ influx and insulin secretion
Antworten
- True
- False
Frage 12
Frage
Which drugs block K+ channels and mimic high glucose?
Antworten
-
Sulpynoylurea
-
Sulphinomides
-
Sulphinomics
Frage 13
Frage
Diazoxide causes insulin secretion by keeping channels open
Antworten
- True
- False
Frage 14
Frage
High doses of adrenaline stimulates insulin secretion through _ receptors
Antworten
-
Alpha 1
-
Alpha 2
-
Beta 1
-
Beta 2
Frage 15
Frage
Low concs of adrenaline inhibit insulin secretion through Beta receptors
Antworten
- True
- False
Frage 16
Frage
Insulin is catabolic
Antworten
- True
- False
Frage 17
Frage
Insulin stimulates _ activity in order to reduce cAMP levels
Antworten
-
Phosphodiesterases
-
Adenylate cyclase
Frage 18
Frage
Which of the following metabolites are reduced?
Antworten
-
Fatty Acyl CoA
-
Acetyl CoA
-
Malonyl CoA
-
Palmitite
Frage 19
Frage
Inc. Phosphorylation of tyrosine kinase by insulin causes what?
Antworten
-
Inc tyrosine kinase activity
-
Inc phosphatase activity
-
Inc Adenylate cyclase activity
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