761837
Beschreibung
Karteikarten von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor etwa 10 Jahre
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| Frage | Antworten |
| Antibiotic Class | Class 2 (Substrates for Macromolecule Production) |
| Target (System) | Folic acid synthesis |
| Requirement of Target | Required to make DNA |
| Selective Toxicity | Humans get folic acid from the diet, bacteria use PABA to make it |
| Main Target (Enzyme) | Dihydropterase Synthase, which are inhibited by Sulphinomides |
| Dihydrofolate Reductase | Present in human cells but structured differently |
| Drug for Dihydrofolate Reductase | Trimethoprim |
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