Asthma Treatment (Long Term)

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Year 2 Karteikarten am Asthma Treatment (Long Term), erstellt von gina_evans0312 am 18/04/2014.
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Karteikarten von gina_evans0312, aktualisiert more than 1 year ago
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Corticosteroids- Example Budenoside
Inhaled Corticosteroids- Effect Red. airway inflammation by red. inflammatory cell infiltration, and odema by acting on vascular endothelium
Inhaled Corticosteroids- Times Long term prophylaxis- 3 to 7 days for full effect
Inhaled Corticosteroids- Side Effects Hoarseness and thrush of mouth/throat
Oral Corticosteroids- Role Reserved for severe, acute attacks- single dose daily for 5 days
Oral Corticosteroids- Side Effects Peptic ulceration, osteoporosis, cateracts, links to diabetes
Cromones- Effect Block mast cells by blocking Cl- channels, prevent mediator secretion
Cromones- Use No longer widely used (useless in acute attacks) but good prophylaxis for allergy associated attacks
Cromones- Time Short duration- take 4x a day
Cromones- Side Effects Few- generally well tolerated
Leukotrine Receptor Agonists- Effect Prevent activation of leukotrine receptors that cause early phase bronchospasm and late phase inflammation
Leukotrine Receptor Agonists- Montelukast (Effect) Selective receptor of LTC4, LTD4 & E4 leading to bronchodilation and red. inflammation
Leukotrine Receptor Agonists- Montelukast (Role) Used for prophylaxis of mild to moderate asthma, especially during exercise/at night
Leukotrine Receptor Agonists- Montelukast (Side Effects) Well tolerated, not really any
Leukotrine Receptor Agonists- Montelukast (Steroid Phobia) Useful for steroid phobics or those with allergy related conditions
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