Quiz
Session 2 - Neurophysiology I
Questions in this quiz (20)
1Which of the following components does NOT dictate the electrical properties of a cell membrane?
- AIonic gradient across the cell membrane
- BIonic channels in the cell membrane
- CNa+/K+-ATPase pump
- DOsmolarity
2Which of the following ions has a greater concentration inside the cell than outside?
- APotassium
- BSodium
- CChloride
- DCalcium
3Which of the following ion channels has a single, straightforward function?
- AVoltage gated sodium ion channels
- BCalcium ion channels
- CPotassium ion channels
4Voltage-gated sodium ion channels are responsible for generating action potentials. They will open when the membrane potential is _________ mV.
- A-50
- B-70
- C50
- D70
5Phenytoin is a common anti-epileptic drug. Which channel does this drug block to prevent seizure activity?
- AVoltage-gated sodium ion channels
- BVoltage-gated potassium ion channels
- CVoltage-gated calcium ion channels
- DLigand gated ion channels
6Which of the following are actions of potassium ion channels? (Select all that apply)
- ADiversifying neuronal electrical properties
- BDiversifying temporal pattern of action potential trains
- CDictating different responses to synaptic input
- DIntracellular signaling
7What is the primary function of the voltage-gated delayed rectifier potassium ion channel?
- ARepolarizing the action potential
- BDepolarizing the action potential
- CSetting the resting membrane potential
- DPace-making
8There are four subtypes of calcium ion channels. Which of the following is NOT a primary function of the T-type channel?
- AElectrical activity of neurons for sleep
- BGI smooth muscles for motility
- CCardiac rhythms
- DNeurotransmitter release
9There are four subtypes of calcium ion channels. Which of the following is a function of the L-type channel?
- AMuscle contraction
- BSmooth muscles for gut motility
- CIntracellular signaling
- DNeurotransmitter release
10The sodium-potassium ATPase pump has three main functions. It exports 3 Na+ for 2 K+ against their concentration gradients. Per action, one net positive charge moves outside of the cell. These maintain the ionic gradients and make the membrane inside the cell ~10-15 mV more negative than the outside. What is the third primary function?
- ABuilding the osmotic gradient - inducing osmosis from inside to outside the cell.
- BBuilding the osmotic gradient - inducing osmosis from outside to inside the cell.
- CCounteracting the osmotic gradient - inhibiting osmosis from inside to outside the cell.
- DCounteracting the osmotic gradient - inhibiting osmosis from outside to inside the cell.
11In some individuals, red blood cells (RBCs) express a high density of Na/K-ATPases to counteract the unusually high permeability of the membrane to Na+. When these RBCs reach and are delayed in the vein of the spleen, what would happen to these RBCs?
- AThey may swell and rupture.
- BThey may shrink in volume.
- CThey may decrease in membrane potential (membrane inside the cell becomes more negative)
- DThey may increase in intracellular potassium.
12If you have a membrane that is impermeable to both sodium and potassium ions, what is the resting membrane potential?
- A0 mV
- B-90 mV
- C-70 mV
- D60 mV
13If you are observing a cell that is only permeable to potassium ions, what would you expect the equilibrium potential to be?
- A-90 mV
- B-70 mV
- C60 mV
- D0 mV
14What would the membrane potential of a cell be if it were only permeable to sodium ions?
- A60 mV
- B90 mV
- C-90 mV
- D-60 mV
15At resting conditions, we know that the membrane potential of a neuron is about -70 mV. From this value, we can conclude:
- APK > PNa at resting conditions
- BPNa > PK at resting conditions
- CPK = PNa at resting conditions
16Which of the following are involved in determining the K+ equilibrium potential of a neuron? (Select all that apply)
- ANa+ gradient
- BK+ gradient
- CK+ channel density
- DMembrane permeability to K+
17The equilibrium potential will change if...
- Athe ionic gradient changes
- Bthe resting membrane potential remains constant
- Csodium and potassium are moved in and out of the cell proportionately
18You have a patient in kidney failure. They are not regulating K+ ions in the extracellular fluid. As a result, the extracellular K+ level has increased from 5 mM to 15 mM. How would this affect brain function?
- AAction potentials will occur more easily
- BAction potentials will not occur as easily
- CThere will be no change in action potential generation
19The presence of leak potassium channels, which are always open:
- ADrives the membrane potential towards the potassium equilibrium potential (-90 mV)
- BDrives the membrane potential towards the potassium equilibrium potential (-70 mV)
- CDrives the membrane potential towards the sodium equilibrium potential (-90 mV)
- DDrives the membrane potential towards the sodium equilibrium potential (60 mV)
20What will happen to the resting membrane potential if we block half of the leak potassium ion channels in the membrane?
- AIt will increase
- BIt will decrease
- CIt will not change
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- PA School Physiology Quiz on Session 2 - Neurophysiology I, created by Kathleen Lonergan on 13/06/2019.
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- Kathleen Lonergan
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- English
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