Quiz
Linkage Analysis
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Questions in this quiz (19)
1Metaphase is the most important stage for genetic mapping
- ATrue
- BFalse
2Recombination cannot be detected in...
- AHomozygotes
- BHeterozygotes
- CBecause both alleles are different
- DBecause both alleles are identical
3What indicates linkage?
- AThe no of recombinants
- BThe no of homozygotes
- CThe no of heterozygotes
4A generation bred from parents AB & ab, has 1 recombinant out of 20- is linkage involved
- AYes
- BNo
5Recombinant detecting probes can be fooled if double recombination occurs
- ATrue
- BFalse
6Which of the following gametes tend to recombine more around the centromere?
- ASpermatocytes
- BOocytes
7Oocytes tend to recombine
- AAround the telomeres
- BAround the centromere
- CMore than spermatocytes
- DLess than spermatocytes
8Most recombination occurs at random
- ATrue
- BFalse
9What is 1q42.3 referring to?
- AShort arm of chromosome 1
- BLong arm of chromosome 1
- CLocus position (from telomere to centromere)
- DLocus position (from centromere to telomere)
10Meiosis is made informative or uninformative depending on whether you can track the diseased allele
- ATrue
- BFalse
11What must be known for effective meosic analysis?
- AGrandparent -> Grandchild phenotype
- BGrandchild & all siblings phenotype
- CParent & all siblings -> Grandchild phenotype
12Is the following informative for linkage analysis?
- AYes- the child is a recombinant
- BNo- the child is heterozygous
- CNo- the father is homozygous
13How would you classify this?
- AUninformative non-recombinant
- BInformative recombinant
- CInformative Non-recombinant
14This is an informative recombinant
- ATrue
- BFalse
15What is true of Recombinant/Human Pedigree Analysis?
- AThe lower the recombination frequency, the more likely the hypothysis is to be correct
- BThe higher the recombination frequency, the more likely the hypothysis is to be correct
16A mother has a disease, and has the alleles M1 & M2- what are the two hypothesis for pedigree analysis?
- AM1 is diseased
M2 is healthy - BM1 is healthy
M2 is diseased - CM1 & M2 are healthy
- DM1 & M2 are diseased
- AM1 is diseased
17Give the two Recombination frequencies for that above image
- A0.16 & 0.83
- B1.66 & 8.33
- C16.66 & 83.33
18A higher recombination frequency means alleles are closer together
- ATrue
- BFalse
19Define a Marker
- AAny mendelian character that can be used to follow a disease through a pedigree
- BA fluorescent dye used to find particular alleles
- CA mutagen used to create findable mutations
Information
- Description
- Year 2 Quiz on Linkage Analysis, created by gina_evans0312 on 26/12/2013.
- Author
- gina_evans0312
- Language
- English
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