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CANCER

Is a disease that arise in an individual's body

uncontrolled cell division

Growth without "go" (+) signals.

Failure to respond to "stop" (-) signals.

Evation of programmed cell death (apoptosis)

sustained angiogenesis (stimulation of blood vessel growth)

Unlimited cell division

Tissue invasion and metastasis

Unique properties of cell cancers

from one faulty cell

genetic changes

proto-oncogenes provide go signals and tumor suppressors provide stop signals

a cell with a gain or loss of function mutation in a. tumor suppressor and in a proto-oncogene gene is more predisposed to becoming cancer.