Flashcards
Antihelmintics
Cards in this deck (35)
- 1Types of helminthsNematodes
Platyhelminths - 2Fancy word for wormsHelminths
- 3PlatyhelminthesFlatworms:
1) Trematodes (Flukes)
2) Cestodes (Tapeworms) - 4Most anthelmintics areselectively toxic
- 5NematodesRound worms
- 6LevamisoleGood oral absorption
Excitatory
Causes spastic paralysis of worms
Worms are expelled in the faeces as a result - 7IvermectinEnhance GABA
Causes flaccid paralysis of worms
Effective against most nematodes - 8PiperazineGABA agonist
Causes flaccid paralysis of worms - 9Platyhelminthes lackGABA nerves
- 10PraziquantelIncreases Ca influx in worms
Causes spastic paralysis
Worms are detached as a result
Effective against platyhelminthes - 11MebendazoleBind to beta-tubulin of nematodes
Transport of secretory granules and other organelles is inhibited as a result - 12Drugs used to treat systemic helminthic infectionsDiethylcarbamazine
Ivermectin - 13Filariasissystemic helminthic infection
- 14Types of intestinal nematodesHookworm
Threadworm
Whipworm
Roundworm
Strongyloides - 15Drug of choice for schistosoma infectionsPraziquantel
- 16Drugs effective against roundwormsMebendazole
Levamisole
Piperazine - 17Possible side effects of PiperazineVomiting
Diarrhea - 18Roundworms usually:Infect gut lumen
10 - 30 cm long - 19Hookworm1 cm long
Infect gut by:
Ancylostoma duodenale
OR
Necator americanus
Common cause of Iron-deficiency anemia - 20Ascaris lumbricoidesCommon roundworm
- 21Treat HookwormMebendazole
- 22Treat StrongyloidesTiabendazole
Albendazole
Ivermectin - 23Another name for ThreadwormPinworm
- 24Example of a ThreadwormEnterobius vermicularis
- 25Threadworm infection isCommon in children
Can cause pruritus ani (Itchy bottom) - 26Treatment against threadwormMebendazole
Whole family is usually treated - 27Filarial infectionTransmitted by blood-sucking worm insects
- 28Lymphatic filiariasisCaused by: Brugia timori, Brugia malayi, OR Wuchereria bancrofti
Transmitted by mosquitoes - 29Treat against filiarial infectionsIvermectin
OR
Diethylcarbamazine - 30Schistosoma infectionsBladder & urinary tract (S. haematobium)
Intestine (S. mansoni OR S. japonicum) - 31Tapeworm infectionUndercooked, infected:
i) Beef (Taenia. saginita)
ii) Pork (Taenia. solium)
Uncooked, infected fish: Diphyllobrothium latum - 32Treat against tapewormNiclosamide
- 33Pyrantel pamoateCauses spastic paralysis by inhibiting acetylcholinesterase
Treat against nematodes - 34Treat against Taenia soliumAlbendazole
- 35ThiabendazoleDecreases ATP production
Decreased glucose uptake as a result
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- Bachelors Anti-infectives (Anthelmintics) Flashcards on Antihelmintics, created by wade.barrett777 on 14/03/2015.
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